Rational design and synthesis of novel triazole- and tetrazole-fused iminosugars as potential inhibitors of amyotrophic lateral sclerosis (ALS) linked SOD1 aggregation.

Santhanam, Venkatesan; Modi, Priya; Mishra, Umesh K; Jahan, Ishrat; Ramesh, Namakkal G; Deep, Shashank

Santhanam, Venkatesan; Modi, Priya; Mishra, Umesh K; Jahan, Ishrat; Ramesh, Namakkal G; Deep, Shashank.

Afiliação

Santhanam V; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Modi P; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Mishra UK; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Jahan I; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Ramesh NG; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India. Electronic address: ramesh@chemistry.iitd.ac.in.
Deep S; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India. Electronic address: sdeep@chemistry.iitd.ac.in.

Int J Biol Macromol ; 253(Pt 4): 126900, 2023 Dec 31.

Article em En | MEDLINE | ID: mdl-37714236

Assuntos

Esclerose Lateral Amiotrófica; Humanos; Superóxido Dismutase-1/genética; Superóxido Dismutase/genética; Mutação

Palavras-chave

Amyotrophic lateral sclerosis; Carbohydrates; Iminosugars; Superoxide dismutase-1; Triazoles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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