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The solution structure of the heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions.
Gao, Xin; Thrush, Joseph W; Gor, Jayesh; Naismith, James H; Owens, Raymond J; Perkins, Stephen J.
Afiliação
  • Gao X; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom.
  • Thrush JW; Department of Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus, Didcot, United Kingdom.
  • Gor J; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom.
  • Naismith JH; Department of Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus, Didcot, United Kingdom.
  • Owens RJ; Department of Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus, Didcot, United Kingdom.
  • Perkins SJ; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, United Kingdom. Electronic address: s.perkins@ucl.ac.uk.
J Biol Chem ; 299(11): 105337, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37838175

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cadeias Pesadas de Imunoglobulinas / SARS-CoV-2 / Anticorpos Antivirais Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cadeias Pesadas de Imunoglobulinas / SARS-CoV-2 / Anticorpos Antivirais Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido