Fluorine-NMR studies of chimpanzee hemoglobin.
Biochim Biophys Acta
; 874(3): 372-4, 1986 Dec 12.
Article
em En
| MEDLINE
| ID: mdl-3790577
ABSTRACT
It has been demonstrated that 4-fluorophenylalanine, a known inhibitor of protein synthesis, becomes incorporated into hemoglobin when present in the diet of a chimpanzee. 19F-NMR spectra of various forms of this protein show well-resolved lines, each line presumably corresponding to a unique phenylalanine/fluorophenylalanine position of the primary sequence. Fluorine chemical shifts and, by implication, tertiary structures vary with the oxidation state and ligand.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemoglobinas
Limite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1986
Tipo de documento:
Article