Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis.

Gui, Chun; Kalkreuter, Edward; Liu, Yu-Chen; Li, Gengnan; Steele, Andrew D; Yang, Dong; Chang, Changsoo; Shen, Ben

Gui, Chun; Kalkreuter, Edward; Liu, Yu-Chen; Li, Gengnan; Steele, Andrew D; Yang, Dong; Chang, Changsoo; Shen, Ben.

Afiliação

Gui C; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Kalkreuter E; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Liu YC; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Li G; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Steele AD; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Yang D; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Chang C; Natural Products Discovery Center, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL, USA.
Shen B; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Lemont, IL, USA.

Nat Chem Biol ; 20(2): 243-250, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37945897

Assuntos

Antineoplásicos; Oxigenases; Antraquinonas/química; Antraquinonas/metabolismo; Enedi-Inos/química; Enedi-Inos/metabolismo; Compostos de Epóxi

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigenases / Antineoplásicos Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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