A Molecular Integrative Study on the Inhibitory Effects of WRR and ERW on Amyloid ß Peptide (1-42) Polymerization and Cell Toxicity.

Wu, Zhongyun; Ye, Lianmeng; Yuan, Nan; Che Ajuyo, Nuela Manka'a; Xiao, Zhengpan; Liu, Liangwang; Chen, Zuqian; Pei, Yechun; Min, Yi; Wang, Dayong

Wu, Zhongyun; Ye, Lianmeng; Yuan, Nan; Che Ajuyo, Nuela Manka'a; Xiao, Zhengpan; Liu, Liangwang; Chen, Zuqian; Pei, Yechun; Min, Yi; Wang, Dayong.

Afiliação

Wu Z; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Ye L; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Yuan N; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Che Ajuyo NM; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Xiao Z; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Liu L; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Chen Z; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Pei Y; Laboratory of Biopharmaceuticals and Molecular Pharmacology, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Min Y; Department of Biotechnology, School of Life Sciences, Hainan University, Haikou 570228, China.
Wang D; One Health Cooperative Innovation Center, Hainan University, Haikou 570228, China.

Polymers (Basel) ; 15(22)2023 Nov 08.

Article em En | MEDLINE | ID: mdl-38006082

Palavras-chave

Alzheimer's disease; Aß42; ERW; WRR; inhibitors; molecular docking; molecular dynamics; polymerization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Polymers (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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