microRNA-365 attenuated intervertebral disc degeneration through modulating nucleus pulposus cell apoptosis and extracellular matrix degradation by targeting EFNA3.

Jiang, Chao; Liu, Youjun; Zhao, Weigong; Yang, Yimin; Ren, Zhiwei; Wang, Xiaohui; Hao, Dingjun; Du, Heng; Yin, Si

Jiang, Chao; Liu, Youjun; Zhao, Weigong; Yang, Yimin; Ren, Zhiwei; Wang, Xiaohui; Hao, Dingjun; Du, Heng; Yin, Si.

Afiliação

Jiang C; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liu Y; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhao W; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yang Y; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ren Z; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang X; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Hao D; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Du H; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yin S; Department of Orthopedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

J Cell Mol Med ; 28(2): e18054, 2024 Jan.

Article em En | MEDLINE | ID: mdl-38009813

Assuntos

Degeneração do Disco Intervertebral; Disco Intervertebral; MicroRNAs; Núcleo Pulposo; Ratos; Animais; MicroRNAs/metabolismo; Degeneração do Disco Intervertebral/genética; Degeneração do Disco Intervertebral/metabolismo; Núcleo Pulposo/metabolismo; Metaloproteinase 13 da Matriz/genética; Metaloproteinase 13 da Matriz/metabolismo; Efrina-A3; Agrecanas/genética; Agrecanas/metabolismo; Matriz Extracelular/metabolismo; Apoptose/genética; Colágeno/metabolismo; Disco Intervertebral/metabolismo

Palavras-chave

apoptosis; ephrin-A3; extracellular matrix; intervertebral disc degeneration; miR-365

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Degeneração do Disco Intervertebral / Núcleo Pulposo / Disco Intervertebral Limite: Animals Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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