Cadmium exposure exacerbates immunological abnormalities in a BTBR T<sup>+</sup> Itpr3<sup>tf</sup>/J autistic mouse model by upregulating inflammatory mediators in CD45R-expressing cells.

Albekairi, Thamer H; Alanazi, Mohammed M; Ansari, Mushtaq A; Nadeem, Ahmed; Attia, Sabry M; Bakheet, Saleh A; Al-Mazroua, Haneen A; Aldossari, Abdullah A; Almanaa, Taghreed N; Alwetaid, Mohammad Y; Alqinyah, Mohammed; Alnefaie, Hajar O; Ahmad, Sheikh F

Cadmium exposure exacerbates immunological abnormalities in a BTBR T⁺ Itpr3^tf/J autistic mouse model by upregulating inflammatory mediators in CD45R-expressing cells.

Albekairi, Thamer H; Alanazi, Mohammed M; Ansari, Mushtaq A; Nadeem, Ahmed; Attia, Sabry M; Bakheet, Saleh A; Al-Mazroua, Haneen A; Aldossari, Abdullah A; Almanaa, Taghreed N; Alwetaid, Mohammad Y; Alqinyah, Mohammed; Alnefaie, Hajar O; Ahmad, Sheikh F.

Afiliação

Albekairi TH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alanazi MM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ansari MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Nadeem A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Attia SM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Bakheet SA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Mazroua HA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Aldossari AA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Almanaa TN; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Alwetaid MY; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Alqinyah M; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alnefaie HO; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ahmad SF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: fashaikh@ksu.edu.sa.

J Neuroimmunol ; 386: 578253, 2024 01 15.

Article em En | MEDLINE | ID: mdl-38064869

Assuntos

Transtorno do Espectro Autista; Transtorno Autístico; Camundongos; Animais; Transtorno Autístico/induzido quimicamente; Transtorno Autístico/genética; Fator Estimulador de Colônias de Granulócitos e Macrófagos/farmacologia; Cádmio/toxicidade; Cádmio/metabolismo; NF-kappa B/metabolismo; Encéfalo/metabolismo; Mediadores da Inflamação/metabolismo; Interleucina-6/metabolismo; RNA Mensageiro; Modelos Animais de Doenças; Camundongos Endogâmicos C57BL; Camundongos Endogâmicos

Palavras-chave

Autism spectrum disorder; BTBR T(+) Itpr3(tf)/J mice; CD45R cells; Cadmium; Inflammatory mediators

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Transtorno do Espectro Autista Limite: Animals Idioma: En Revista: J Neuroimmunol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Arábia Saudita

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