HIV-associated nemaline myopathy manifesting as bent spine syndrome.
BMJ Case Rep
; 17(3)2024 Mar 12.
Article
em En
| MEDLINE
| ID: mdl-38471704
ABSTRACT
HIV-associated myopathies include HIV-associated polymyositis, inclusion body myositis, diffuse infiltrative lymphocytosis syndrome and sporadic late-onset nemaline myopathy (HIV-NM). HIV-NM typically manifests as a painless, progressive proximal and axial muscle weakness with characteristic histological findings of intracytoplasmic rods, or nemaline bodies, seen in atrophic muscle fibres. HIV-NM presents prior to or shortly after initiation of antiretroviral therapy (ART) and is treated with intravenous immunoglobulin, glucocorticoids or immunosuppression. We present a case of HIV-NM in a patient with well-controlled HIV on decades-long ART with progressive bent spine syndrome, or camptocormia. This case highlights the importance of considering HIV-associated myopathies such as HIV-NM in patients with HIV who present with musculoskeletal complaints.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Curvaturas da Coluna Vertebral
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Atrofia Muscular Espinal
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Infecções por HIV
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Miopatias da Nemalina
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Miosite de Corpos de Inclusão
Limite:
Humans
Idioma:
En
Revista:
BMJ Case Rep
/
BMJ case reports
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos