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Light-Driven Access to Selenium-Substituted Thiazole-2-imine Derivatives.
Li, Tangle; Hu, Dandan; Huang, Yiwen; Zhou, Yu; Zhang, Jun-Qi; Zhang, Chun; Zhang, Yili; Hou, Yanan; Ren, Hongjun.
Afiliação
  • Li T; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Hu D; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Huang Y; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Zhou Y; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Zhang JQ; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Zhang C; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Zhang Y; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Hou Y; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
  • Ren H; Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang 318000, China.
J Org Chem ; 89(8): 5328-5336, 2024 Apr 19.
Article em En | MEDLINE | ID: mdl-38595055
ABSTRACT
The thiazole-2-imine derivatives with interesting pharmacological activities have attracted significant attention. However, previously reported synthesis strategies usually suffered from some drawbacks, such as the use of metals/additive and harsh reaction conditions. Herein, we developed a metal- and photoinitiator-free photocatalytic strategy for the synthesis of various selenium-substituted thiazole-2-imine derivatives for the first time. The reaction displayed mild reaction conditions, simple operation, a broad substrate scope (37 examples), and good to excellent yields.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China