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An explainable AI-assisted web application in cancer drug value prediction.
Kothari, Sonali; Sharma, Shivanandana; Shejwal, Sanskruti; Kazi, Aqsa; D'Silva, Michela; Karthikeyan, M.
Afiliação
  • Kothari S; Symbiosis Institute of Technology - Pune Campus, Symbiosis International (Deemed University), Pune, India.
  • Sharma S; Symbiosis Institute of Technology - Pune Campus, Symbiosis International (Deemed University), Pune, India.
  • Shejwal S; Symbiosis Institute of Technology - Pune Campus, Symbiosis International (Deemed University), Pune, India.
  • Kazi A; Symbiosis Institute of Technology - Pune Campus, Symbiosis International (Deemed University), Pune, India.
  • D'Silva M; Symbiosis Institute of Technology - Pune Campus, Symbiosis International (Deemed University), Pune, India.
  • Karthikeyan M; Senior Principal Scientist, Chemical Engineering and Process Development, NCL-CSIR, Pune, India.
MethodsX ; 12: 102696, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38633421
ABSTRACT
In recent years, there has been an increase in the interest in adopting Explainable Artificial Intelligence (XAI) for healthcare. The proposed system includes•An XAI model for cancer drug value prediction. The model provides data that is easy to understand and explain, which is critical for medical decision-making. It also produces accurate projections.•A model outperformed existing models due to extensive training and evaluation on a large cancer medication chemical compounds dataset.•Insights into the causation and correlation between the dependent and independent actors in the chemical composition of the cancer cell. While the model is evaluated on Lung Cancer data, the architecture offered in the proposed solution is cancer agnostic. It may be scaled out to other cancer cell data if the properties are similar. The work presents a viable route for customizing treatments and improving patient outcomes in oncology by combining XAI with a large dataset. This research attempts to create a framework where a user can upload a test case and receive forecasts with explanations, all in a portable PDF report.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: MethodsX Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: MethodsX Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia