Effectiveness of early high-flow nasal oxygen therapy after extubation of patients in the intensive care unit.
J Crit Care
; 83: 154840, 2024 Oct.
Article
em En
| MEDLINE
| ID: mdl-38810601
ABSTRACT
PURPOSE:
This study aimed to evaluate the impact of early high-flow nasal oxygen (HFNO) therapy initiation using a pre-determined respiratory rateoxygenation (ROX) index on reducing reintubation rates and duration of intensive care unit (ICU) stay in post-extubated patients. MATERIALS ANDMETHODS:
We enrolled a total of 145 extubated patients (mean age 67.1 ± 12.9 years; sex 96 male and 49 female; acute physiology and chronic health evaluation II score 18.4 ± 6.8 points) classified into two groups 71 patients admitted to the ICU before establishing extubation criteria and 74 patients after criteria implementation, over a 6-month period. We compared the HFNO reintubation rates and ROX index at 2 h post-extubation before and after implementing early HFNO criteria.RESULTS:
The utilization rate of HFNO pre- and post-establishment of early HFNO criteria did not differ significantly (19.7% vs. 17.6%). However, the reintubation rate significantly decreased (11.3% vs. 4.1%, P < 0.05) with early HFNO use. Additionally, significant differences were observed in the total intubation period (5.2 ± 7.0 vs. 2.5 ± 2.7 days, P < 0.05) and ICU duration (8.6 ± 9.7 vs. 5.8 ± 5.6 days, P < 0.05).CONCLUSIONS:
Early initiation of HFNO guided by the ROX index threshold post-extubation in patients admitted to ICU is associated with reduced reintubation rates and shorter ICU stays.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxigenoterapia
/
Extubação
/
Unidades de Terapia Intensiva
/
Tempo de Internação
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Crit Care
/
J. crit. care
/
Journal of critical care
Assunto da revista:
TERAPIA INTENSIVA
Ano de publicação:
2024
Tipo de documento:
Article