Advancements in combining targeted therapy and immunotherapy for colorectal cancer.
Trends Cancer
; 10(7): 598-609, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38821852
ABSTRACT
Colorectal cancer (CRC) is a prevalent gastrointestinal cancer posing significant clinical challenges. CRC management traditionally involves surgery, often coupled with chemotherapy. However, unresectable or metastatic CRC (mCRC) presents a complex challenge necessitating innovative treatment strategies. Targeted therapies have emerged as the cornerstone of treatment in such cases, with interventions tailored to specific molecular attributes. Concurrently, immunotherapies have revolutionized cancer treatment by harnessing the immune system to combat malignant cells. This review explores the evolving landscape of CRC treatment, focusing on the synergy between immunotherapies and targeted therapies, thereby offering new avenues for enhancing the effectiveness of therapy for CRC.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Terapia de Alvo Molecular
/
Imunoterapia
Limite:
Humans
Idioma:
En
Revista:
Trends Cancer
Ano de publicação:
2024
Tipo de documento:
Article