Phosphonomycin, a new antibiotic produced by strains of streptomyces.

Hendlin, D; Stapley, E O; Jackson, M; Wallick, H; Miller, A K; Wolf, F J; Miller, T W; Chaiet, L; Kahan, F M; Foltz, E L; Woodruff, H B; Mata, J M; Hernandez, S; Mochales, S

Hendlin, D; Stapley, E O; Jackson, M; Wallick, H; Miller, A K; Wolf, F J; Miller, T W; Chaiet, L; Kahan, F M; Foltz, E L; Woodruff, H B; Mata, J M; Hernandez, S; Mochales, S.

Science ; 166(3901): 122-3, 1969 Oct 03.

Article em En | MEDLINE | ID: mdl-5809587

ABSTRACT

ABSTRACT

Phosphonomycin is a newly discovered antibiotic produced by streptomycetes. It is effective, when administered by the oral route, to mice infected with Gram-positive or Gram-negative microorganisms. The antibiotic is bactericidal and inhibits cell-wall synthesis.

Assuntos

Antibacterianos/uso terapêutico; Infecções/tratamento farmacológico; Streptomyces/metabolismo; Animais; Antibacterianos/biossíntese; Antibacterianos/isolamento & purificação; Antibacterianos/farmacologia; Bactérias/efeitos dos fármacos; Parede Celular/efeitos dos fármacos; Camundongos

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Infecções / Antibacterianos Limite: Animals Idioma: En Revista: Science Ano de publicação: 1969 Tipo de documento: Article

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