Detection of infectious centers in C57BL/Ka lymphoid cell populations infected in vitro by the radiation leukemia virus.
Cancer Res
; 40(3): 544-9, 1980 Mar.
Article
em En
| MEDLINE
| ID: mdl-6258781
ABSTRACT
The cocultivation of nonproducer lymphoma cells derived from a radiation-induced lymphoma of the C57BL/Ka mouse with cultures of lymphoid cell populations from the thymus, spleen, and marrow of the same strain 48 hr after their infection by the C57BL/Ka leukemia viruses permits the detection of infectious centers in these cultures. A quantitative assay is described which allows the estimation in lymphoid cell subpopulations of the numbers of target cells susceptible to productive infection by the thymotropic and leukemogenic viruses of C57BL/Ka mice in vitro. This assay should greatly facilitate the identification and characterization of such target cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos
/
Leucemia Experimental
/
Vírus da Leucemia Murina
/
Camundongos Endogâmicos C57BL
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Cancer Res
Ano de publicação:
1980
Tipo de documento:
Article