Plasma concentrations of isoniazid in children with tuberculous infections.
Pediatrics
; 67(6): 876-8, 1981 Jun.
Article
em En
| MEDLINE
| ID: mdl-7232051
ABSTRACT
Six children with tuberculous infection were given their daily prescribed doses of isoniazid by the oral and the intramuscular route on different days. The plasma concentrations reached after both routes of administration were nearly equivalent. The plasma half-life of isoniazid ranged from 1.6 to 4.8 hours. The observed plasma concentrations in these children were higher than those reported in many adults. This difference is due to the larger doses of isoniazid prescribed for children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Meníngea
/
Tuberculose Pulmonar
/
Isoniazida
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Pediatrics
Ano de publicação:
1981
Tipo de documento:
Article