A randomized, comparative study of a single oral dose of fluconazole versus a single topical dose of clotrimazole in the treatment of vaginal candidosis among general practitioners and gynaecologists.
Eur J Obstet Gynecol Reprod Biol
; 55(2): 123-7, 1994 Jun 15.
Article
em En
| MEDLINE
| ID: mdl-7958150
ABSTRACT
OBJECTIVES:
To compare efficacy, acceptability and patient preference of a single oral dose of fluconazole with a single intravaginal dose of 500 mg clotrimazole (medication groups) in women with vaginal candidosis visiting gynaecologists or general practitioners (study groups).DESIGN:
A comparative, randomized multicenter study. EVENTS Baseline visit and treatment, short-term follow-up after 1 week and long-term follow-up after 4 weeks. At each visit, symptoms were graded and cultures were obtained.RESULTS:
Symptomatic and mycological efficacy did not differ statistical significant in the medication groups or study groups. A complicated history regarding vaginal candidosis was more often found among gynaecologists, yielding poorer results of treatment. Patients preferred oral treatment over intra-vaginal treatment.CONCLUSIONS:
No differences were found in the clinical and mycological efficacy of both drugs. Clinical results were related to parameters originating from the patients history, resulting in less favourable results in the study group of gynaecologists.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candidíase Vulvovaginal
/
Fluconazol
/
Satisfação do Paciente
/
Clotrimazol
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Obstet Gynecol Reprod Biol
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Holanda