Effect of dithiothreitol on angiotensin II receptor type II in rat ovarian cultured granulosa cells.
Biochim Biophys Acta
; 1192(2): 286-8, 1994 Jun 22.
Article
em En
| MEDLINE
| ID: mdl-8018710
ABSTRACT
Dithiothreitol markedly increased the ligand binding affinity of angiotensin II (AII) receptor type II (AT2) without affecting its antagonist selectivity in cultured ovarian granulosa cells, demonstrating that this AT2 is of the dithiothreitol-sensitive type. Dithiothreitol is useful for specifically detecting low levels of the AT2 in the ovary, where it plays roles that are probably related to atresia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores de Angiotensina
/
Ditiotreitol
/
Células da Granulosa
Limite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Japão