Effect of lysophosphatidic acid on the preimplantation development of mouse embryos.
FEBS Lett
; 351(1): 38-40, 1994 Aug 29.
Article
em En
| MEDLINE
| ID: mdl-8076690
ABSTRACT
The effect of lysophosphatidic acid (LPA) on the preimplantation development of mouse embryos was examined. The blastocyst rates from 2-cell and 4-cell stage embryos were significantly higher in the presence of LPA at the pronuclear stage. However, the blastocyst rate from 4-cell stage embryos was significantly lower when LPA was added to the medium at the 4-cell stage than when it was added at the pronuclear stage. Furthermore, pretreatment of pronuclear stage embryos with pertussis toxin suppressed LPA-induced embryo development, suggesting that it is probably mediated by a Gi-protein-linked receptor.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lisofosfolipídeos
/
Desenvolvimento Embrionário
/
Desenvolvimento Embrionário e Fetal
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
FEBS Lett
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Japão