Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults.
Pediatr Infect Dis J
; 15(1): 14-17, 1996 Jan.
Article
em En
| MEDLINE
| ID: mdl-8684870
ABSTRACT
BACKGROUND:
A belief that brand oral liquid medications taste better than their generic counterparts may influence prescribing habits among pediatricians.METHODS:
We undertook a prospective, randomized, double blinded, comparative evaluation of the taste of brand and generic erythromycin ethylsuccinate, cephalexin monohydrate, erythromycin ethylsuccinate/sulfisoxazole, penicillin V potassium and trimethoprim-sulfamethoxazole in 42 adult volunteers. Subjects tasted one class of brand and generic antibiotics and rated them according to smell, texture, taste and aftertaste.RESULTS:
At least one generic preparation of cephalexin, erythromycin ethylsuccinate/sulfisoxazole and penicillin V potassium was rated equal in taste to the respective brand name products. However, brand erythromycin estolate and trimethoprim-sulfamethoxazole name brand suspensions rated significantly higher than the other products tested.CONCLUSIONS:
Based on our results brand name oral antibiotic formulations do not necessarily taste better than their generic counterparts.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Olfato
/
Paladar
/
Medicamentos Genéricos
/
Antibacterianos
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Pediatr Infect Dis J
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
PEDIATRIA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos