Modulation of mRNA levels in the presence of thymocytes and genome mapping for a set of genes expressed in mouse thymic epithelial cells.
Immunogenetics
; 46(2): 142-51, 1997.
Article
em En
| MEDLINE
| ID: mdl-9162101
ABSTRACT
Modulation of gene expression in mouse thymic epithelium upon culture in the presence of thymocytes (coculture) was studied by comparison of hybridization signatures on a set of nearly 5000 mouse thymus cDNA clones. Forty-nine differentially expressed clones (usually down-regulated in coculture) were characterized by tag sequencing. Many of them corresponded to entities that had not been described previously in the mouse, and were further characterized by genome mapping. This set of genes appears to be involved in growth regulation and differentiation within the thymus.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Timo
/
RNA Mensageiro
/
Linfócitos T
/
Regulação da Expressão Gênica
/
Mapeamento Cromossômico
Limite:
Animals
Idioma:
En
Revista:
Immunogenetics
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
França