Using nasal intermittent positive pressure ventilation on a general respiratory ward.
J R Coll Physicians Lond
; 32(3): 219-24, 1998.
Article
em En
| MEDLINE
| ID: mdl-9670147
ABSTRACT
OBJECTIVES:
To assess the use of nasal intermittent positive pressure ventilation (NIPPV) in treating acute-on-chronic respiratory failure in a general medical ward.DESIGN:
Retrospective analysis of clinical outcome.SETTING:
A general medical ward of a tertiary respiratory medicine referral centre.SUBJECTS:
Altogether 75 patients admitted with acute exacerbations of chronic respiratory failure and treated NIPPV. MAIN OUTCOMEMEASURES:
Blood gas tensions determined at admission to hospital and during NIPPV, tolerance of NIPPV and mortality.RESULTS:
During treatment with NIPPV, the mean (SD) PaO2 increased rapidly by 2.31 (3.58) kPa (p < 0.0001), while the mean PaCO2 fell by 1.07 (1.74) kPa (p < 0.0001) and the mean pH increased by 0.03 (0.07) (p = 0.001). Altogether 57 (76%) of patients tolerated NIPPV, and (9.3%) died in hospital. Improvement in PaO2 was more noticeable in patients with chronic obstructive pulmonary disease (+3.13 (3.49) kPa, p < 0.0001) than in those with restrictive chest wall disease (+1.20 (3.07) kPa, p = 0.25) or obstructive sleep apnoea (+0.18 (3.64), p = 0.88). The reduction in PaCO2 was similar in all three groups.CONCLUSIONS:
In routine treatment of unselected patients with acute-on-chronic respiratory failure who are being cared for on a general ward, NIPPV rapidly improves hypoxaemia and hypercapnia, is well tolerated and is associated with low mortality.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Insuficiência Respiratória
/
Ventilação com Pressão Positiva Intermitente
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J R Coll Physicians Lond
Ano de publicação:
1998
Tipo de documento:
Article