Detalhe da pesquisa
1.
Crucial role of the NSE1 RING domain in Smc5/6 stability and FANCM-independent fork progression.
Cell Mol Life Sci
; 81(1): 251, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38847937
2.
Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage.
EMBO J
; 39(13): e103838, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32484960
3.
α4-α5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death.
Int J Mol Sci
; 24(1)2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36614192
4.
OZF is a Claspin-interacting protein essential to maintain the replication fork progression rate under replication stress.
FASEB J
; 34(5): 6907-6919, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267586
5.
Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse.
Cell Mol Life Sci
; 77(4): 735-749, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31297568
6.
Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease.
Int J Mol Sci
; 21(10)2020 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32456244
7.
Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.
FASEB J
; 32(7): 3502-3517, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29452566
8.
Modeling and subtleties of K-Ras and Calmodulin interaction.
PLoS Comput Biol
; 14(10): e1006552, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30376570
9.
New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress.
Nucleic Acids Res
; 44(10): 4745-62, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26939887
10.
Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status.
J Cell Sci
; 126(Pt 20): 4553-9, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943869
11.
Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.
Gastroenterology
; 147(4): 882-892.e8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24998203
12.
Nucleolar disruption ensures nuclear accumulation of p21 upon DNA damage.
Traffic
; 11(6): 743-55, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20331843
13.
Proteasome inhibition reduces proliferation, collagen expression, and inflammatory cytokine production in nasal mucosa and polyp fibroblasts.
J Pharmacol Exp Ther
; 343(1): 184-97, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787116
14.
RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress.
PLoS One
; 17(8): e0266645, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969531
15.
Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds.
Sci Rep
; 12(1): 15810, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36138080
16.
The transcriptional co-activator PCAF regulates cdk2 activity.
Nucleic Acids Res
; 37(21): 7072-84, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19773423
17.
KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer.
Oncogene
; 40(38): 5730-5740, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333552
18.
Toward understanding calmodulin plasticity by molecular dynamics.
Future Med Chem
; 11(9): 975-991, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31140879
19.
Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.
Mol Cell Biol
; 25(16): 7364-74, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16055744
20.
Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway.
Mol Biol Cell
; 13(6): 2057-68, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12058069