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1.
Encephale ; 49(3): 325-327, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36775763

RESUMO

This article develops the WPA's new Code of Ethics that was developed in 2020. It succeeds the Declaration of Hawaii of 1977 and the Declaration of Madrid of 1996. The Code is divided into four sections that cover the practice of psychiatry in clinical practice, education, research and publication as well as public mental health. We will discuss the new ethical issues that this Code raises in parallel with the development of psychiatry and psychiatrists' role in society in recent years.


Assuntos
Códigos de Ética , Psiquiatria , Humanos , Ética Médica
2.
Dev Psychobiol ; 63(6): e22148, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34087947

RESUMO

Biparental care is a hallmark of human social organization, though paternal investment varies between and within societies. The facultative nature of paternal care in humans suggests males should invest when their care improves child survival and/or quality, though testing this prediction can be challenging because of the difficulties of empirically isolating paternal effects from those of other caregivers. Additionally, the broader context in which care is provided, vis-à-vis care from mothers and others, may lead to different child outcomes. Here, we examine the effects of paternal care on child growth among Shodagor fisher-traders, where fathers provide high levels of both additive and substitutive care, relative to mothers. We modeled seasonal z-scores and velocities for height, weight, and body mass index (BMI) outcomes using linear mixed models. Our evidence indicates that, as predicted, the context of paternal care is an important predictor of child outcomes. Results show that environmental seasonality and alloparental help contribute to a nuanced understanding of the impact of Shodagor paternal care on child physiology.


Assuntos
Pai , Mães , Índice de Massa Corporal , Cuidadores , Criança , Feminino , Humanos , Masculino
3.
Environ Monit Assess ; 193(8): 468, 2021 Jul 05.
Artigo em Inglês | MEDLINE | ID: mdl-34226956

RESUMO

Bamboos due to high soil water conservation potential are gaining increased attention in plantation programs across the globe. Large-scale plantation of fast-growing bamboo, however, can have important hydrological consequences. The study aims to quantify the eco-hydrological parameters, viz., throughfall (TF), stemflow (SF), and interception (I) in seven important sympodial bamboo species in north western Himalayan foothills of India. The species selected include Bambusa balcooa, Bambusa bambos, Bambusa vulgaris., Bambusa nutans, Dendrocalamus hamiltonii, Dendrocalamus stocksii, and Dendrocalamus strictus. Throughfall versus gross rainfall (GR) relationship in different species indicated high throughfall production during high rainfall events with r2 > 0.90. Average throughfall was lowest (62.1%) in D. hamiltonii and highest in B. vulgaris (74.6%). SF ranged from 1.32% in B. nutans to 3.39% in D. hamiltonii. The correlation coefficient (r) between leaf area index (LAI), number of culms, and crown area with the interception were 0.746, 0.691, and 0.585, respectively. The funneling ratio (F) was highest (27.0) in D. hamiltonii and least in B. nutans. Canopy storage capacity was highest in D. strictus (3.57 mm) and least in D. hamiltonii (1.09 mm). Interception loss was highest (34.4%) in D. hamiltonii and lowest in B. vulgaris (23.5%) and D. strictus (23.6%). Higher interception in bamboos make them suitable for soil conservation, but careful selection of species is required in low rainfall areas.


Assuntos
Antozoários , Monitoramento Ambiental , Animais , Hidrologia , Índia , Solo
4.
Environ Monit Assess ; 191(3): 177, 2019 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-30793215

RESUMO

Industrialization and globalization have resulted in pollution of all the three ecosystems, including soil, water, and air. Among these, air pollution has generated much interest, since it has a major influence on the transboundary dispersion of pollutants globally. Air pollution tolerance index (APTI) value represents tolerance level of plants which help in selecting the most suitable plant species for plantation in/around affected areas. This parameter in conjunction with Anticipated Performance Index (API) can provide a logical solution for green belt development by considering biological and socio-economic aspect of the species and help in reducing the levels of pollutants. The present study was conducted in Himachal Pradesh, constituting a very vital part of the Indian Himalayan Region. In the present study, APTI and API values of six commonly growing temperate and sub-temperate plant species viz., Quercus leucotrichophora, Rubus ellipticus, Debregeasia saeneb, Hypericum oblongifolium, Punica granatum, and Grevillea robusta, were evaluated along the National Highway-5 in Himachal Pradesh. The highest value of APTI was observed for Grevillea robusta (12.89), followed by Punica granatum (10.87), Debregeasia saeneb (10.50), Hypericum oblongifolium (10.43), Rubus ellipticus (10.18), and Quercus leucotrichophora (9.68). Upon assessment of API, it was observed that Grevillea robusta (62.50%) was the highest scoring plant species in trees, while Rubus ellipticus and Debregeasia saeneb were the highest scoring shrub species (56.25% each) and thus can be recommended for green belt development and attenuation of air pollution in the region. Punica granatum can be suggested for plantation among the native species.


Assuntos
Poluentes Atmosféricos/análise , Monitoramento Ambiental/métodos , Árvores/crescimento & desenvolvimento , Poluentes Atmosféricos/toxicidade , Poluição do Ar/análise , Biodegradação Ambiental , Índia , Folhas de Planta/química , Folhas de Planta/crescimento & desenvolvimento , Árvores/química , Madeira/química , Madeira/crescimento & desenvolvimento
5.
Epidemiol Infect ; 145(16): 3361-3369, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-29168439

RESUMO

Measles is a major cause of childhood morbidity and mortality in many parts of the world. Estimates of the case-fatality rate (CFR) of measles have varied widely from place to place, as well as in the same location over time. Amongst populations that have experienced famine or armed conflict, measles CFR can be especially high, although past work has mostly focused on refugee populations. Here, we estimate measles CFR between 1970 and 1991 in a rural region of Bangladesh, which experienced civil war and famine in the 1970s. We use historical measles mortality data and a mechanistic model of measles transmission to estimate the CFR of measles. We first demonstrate the ability of this model to recover the CFR in the absence of incidence data, using simulated mortality data. Our method produces CFR estimates that correspond closely to independent estimates from surveillance data and we can capture both the magnitude and the change in CFR suggested by these previous estimates. We use this method to quantify the sharp increase in CFR that resulted in a large number of deaths during a measles outbreak in the region in 1976. Most of the children who died during this outbreak were born during a famine in 1974, or in the 2 years preceding the famine. Our results suggest that the period of turmoil during and after the 1971 war and the sustained effects of the famine, is likely to have contributed to the high fatality burden of the 1976 measles outbreak in Matlab.


Assuntos
Surtos de Doenças/história , Surtos de Doenças/estatística & dados numéricos , Sarampo/história , Sarampo/mortalidade , Inanição/história , Bangladesh/epidemiologia , Pré-Escolar , Feminino , História do Século XX , Humanos , Lactente
7.
Acute Med ; 16(4): 164-169, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29300794

RESUMO

Sepsis is a major health care issue and sepsis survivors are often confronted with long-term complications after admission to the intensive care unit (ICU) which may negatively influence their health related quality of life (HRQOL). This study aimed to systematically evaluate the outcome in terms of HRQOL in patients with sepsis after ICU discharge. A literature search was conducted in the bibliographic databases PubMed, EMBASE, and CINAHL, including reference lists of published guidelines, reviews and associated articles. Sixteen studies were included, thirteen (81.3%) reported that sepsis survivors suffer from impaired HRQOL in physical and mental domains which persist from months to years after a sepsis episode. More focus on improving long-term outcomes for patients surviving sepsis and the ICU is needed.

8.
Colorectal Dis ; 18(1): 37-44, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26542191

RESUMO

AIM: Recent advances in the treatment of fistula-in-ano have focused on surgical techniques that preserve sphincter integrity. Plugs that obliterate the lumen of the fistula track have been proposed as one such method, and may be derived from biological or delayed absorbable synthetic materials. Biological plugs have highly variable results and have not been widely adopted. The aim of this systematic review was to assess the effectiveness and safety of a delayed absorbable synthetic plug (GORE® BIO-A®) for treatment of anal fistula. METHOD: A systematic review of all literature in the English language relevant to the use of a plug to treat anal fistula and published between 1 January 2008 and 15 February 2015 was carried out by searching MEDLINE, EMBASE and the Cochrane Library of Systematic Reviews/Controlled Trials for relevant literature. Relevant articles were identified, quality assessed using the methodological index for nonrandomized studies criteria and data were extracted by two independent researchers (SKN and NNA). The identified articles were assessed with regard to fistula healing rate, duration of follow-up and complication rates related to the use of delayed absorbable synthetic fistula plugs. RESULTS: Twenty six potential articles were identified from the literature search. Using the predefined inclusion and exclusion criteria, six were included in the final analysis, data extraction and data synthesis. Of these included in the review only three were prospective in design. Complete data were available for 187 of the 221 patients who underwent this treatment. The age of the participants ranged from 19 to 82 years. The fistula healing rates were reported to be between 15.8% and 72.7% at a follow-up ranging between 2 and 19 months. Early or delayed plug extrusion occurred in 16 (8.5%) of the 187 patients. Deterioration in continence was reported in 11 (5.8%) of 187 patients. CONCLUSION: There are insufficient high-quality data on the delayed absorbable synthetic (GORE® BIO-A®) fistula plug to draw meaningful conclusions regarding its effectiveness. It does, however, appear to be a simple and safe technique associated with low complication rates and a minor deterioration in continence in a few cases.


Assuntos
Implantes Absorvíveis , Fístula Retal/cirurgia , Humanos , Resultado do Tratamento , Cicatrização
9.
Colorectal Dis ; 18(2): 135-46, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26559167

RESUMO

AIM: There is ambiguity with regard to the optimal management of anal intraepithelial neoplasia (AIN) III. The aim of this review was to assess and compare international/national society guidelines currently available in the literature on the management, treatment and surveillance of AIN III. We also aimed to assess the quality of the studies used to compile the guidelines and to clarify the terminology used in histological assessment. METHOD: An electronic search of PubMed and Embase was performed using the search terms 'anal intraepithelial neoplasia', 'AIN', 'anal cancer', 'guidelines', 'surveillance' and 'management'. Literature reviews and guidelines or practice guidelines in peer reviewed journals from 1 January 2000 to 31 December 2014 assessing the treatment, surveillance or management of patients with AIN related to human papilloma virus were included. The guidelines identified by the search were assessed for the quality of evidence behind them using the Oxford Centre for Evidence-based Medicine 2011 Levels of Evidence. RESULTS: The database search identified 5159 articles and two further guidelines were sourced from official body guidelines. After inclusion criteria were applied, 28 full-text papers were reviewed. Twenty-five of these were excluded, leaving three guidelines for inclusion in the systematic review: those published by the Association of Coloproctology of Great Britain and Ireland, the American Society of Colon and Rectal Surgeons and the Italian Society of Colorectal Surgery. No guidelines were identified on the management of AIN III from human papilloma virus associations and societies. All three guidelines agree that a high index of clinical suspicion is essential for diagnosing AIN with a disease-specific history, physical examination, digital rectal examination and anal cytology. There is interchange of terminology from high-grade AIN (HGAIN) (which incorporates AIN II/III) and AIN III in the literature leading to confusion in therapy use. Treatment varies from immunomodulation and photodynamic therapy to targeted destruction of areas of HGAIN/AIN II/III using infrared coagulation, electrocautery, cryotherapy or surgical excision but with little consensus between the guidelines. Recommendations on surveillance strategies are similarly discordant, ranging from 6-monthly physical examination to annual anoscopy ± biopsy. Over 50% of the recommendations are based on Level 3 or Level 4 evidence and many were compiled using studies that were more than 10 years old. CONCLUSION: Despite concordance regarding diagnosis, there is significant variation in the guidelines over recommendations on the treatment and surveillance of patients with HGAIN/AIN II/III. All three sets of guidelines are based on low level, outdated evidence originating from the 1980s and 1990s.


Assuntos
Neoplasias do Ânus/diagnóstico , Neoplasias do Ânus/terapia , Carcinoma in Situ/diagnóstico , Carcinoma in Situ/terapia , Vigilância da População/métodos , Guias de Prática Clínica como Assunto , Terminologia como Assunto , Gerenciamento Clínico , Fidelidade a Diretrizes , Humanos
10.
Epidemiol Infect ; 142(12): 2530-41, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24534384

RESUMO

The study aimed to determine the geographical diversity in seasonality of major diarrhoeal pathogens among 21 138 patients enrolled between 2010 and 2012 in two urban and two rural sites in Bangladesh under the surveillance system of the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b). Distinct patterns in seasonality were found for rotavirus diarrhoea which peaked in winter across the sites (December and January) and dipped during the rainy season (May) in urban Dhaka, August in Mirpur and July in Matlab, equated by time-series analysis using quasi-Poisson regression model. Significant seasonality for shigellosis was observed in Dhaka and rural Mirzapur. Cholera had robust seasonality in Dhaka and Matlab in the hot and rainy seasons. For enterotoxogenic Escherichia coli (ETEC) diarrhoea, clearly defined seasonality was observed in Dhaka (summer). Understanding the seasonality of such pathogens can improve case management with appropriate therapy, allowing policy-makers to identify periods of high disease burden.


Assuntos
Diarreia/epidemiologia , Diarreia/microbiologia , Estações do Ano , Adolescente , Bangladesh/epidemiologia , Criança , Pré-Escolar , Cólera/epidemiologia , Disenteria Bacilar/epidemiologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Vigilância da População , Infecções por Rotavirus/epidemiologia
11.
PLOS Glob Public Health ; 4(7): e0003384, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38959267

RESUMO

Insufficient progress has been made to reduce morbidity and mortality for women, children and adolescents particularly in Humanitarian and Fragile settings (HFS). Midwives play a critical and unique role in ensuring communities receive quality and safe essential sexual, reproductive, maternal, newborn, child, and adolescent health services. A lack of knowledge exists on the availability and experiences of midwifery services in HFS. This manuscript provides an overview of the midwifery density in HFS and a synthesis of the experiences of women receiving midwifery care, and barriers and facilitators for midwives providing essential SRMNCAH services in HFS. Guided by an expert committee, a concurrent mixed methods approach was applied, using secondary analysis of primary quantitative and qualitative data sources. Quantitative analysis of the global distribution of midwives compared to fragility was undertaken. Qualitative analysis of experiences of receipt and provision of midwifery care was undertaken across four settings providing humanitarian care. There is a critically low density of midwives in humanitarian and fragile settings. Sub-Saharan Africa accounts for the highest levels of fragility yet lowest density of midwives able to provide SRMNCAH services. Lack of finances both constrains midwives from effectively providing services and prevent communities from utilising services. Sub-optimal working conditions through rising workloads, insufficient and/or inconsistent resources were frequently reported to impede midwives from providing care in HFS. Uniquely for HFS, threats to the safety and security of midwives to conduct their work was widely reported. Key facilitators identified included, complex adaptive health system designs to respond effectively to the rapidly changing HFS environment, realisation of supporting "power, agency and status" as instrumental for midwives to provide quality care and promotion of community-centric approaches may enable continuity of care and uptake of essential SRMNCAH services. Midwives are critical to protect the health and well-being of communities. They require urgent protection and prioritisation in HFS areas where the need is greatest.

12.
J Mater Sci Mater Med ; 24(6): 1605-14, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23504088

RESUMO

Two-dimensional (2D) electrospun fibre mats have been investigated as fibrous sheets intended as biomaterials scaffolds for tissue repair. It is recognised that tissues are three-dimensional (3D) structures and that optimisation of the fabrication process should include both 2D and 3D scaffolds. Understanding the relative merits of the architecture of 2D and 3D scaffolds for tendon repair is required. This study investigated three different electrospun scaffolds based on poly(ε-caprolactone) fibres intended for repair of injured tendons, referred to as; 2D random sheet, 2D aligned sheet and 3D bundles. 2D aligned fibres and 3D bundles mimicked the parallel arrangement of collagen fibres in natural tendon and 3D bundles further replicated the tertiary layer of a tendon's hierarchical configuration. 3D bundles demonstrated greatest tensile properties, being significantly stronger and stiffer than 2D aligned and 2D random fibres. All scaffolds supported adhesion and proliferation of tendon fibroblasts. Furthermore, 2D aligned sheets and 3D bundles allowed guidance of the cells into a parallel, longitudinal arrangement, which is similar to tendon cells in the native tissue. With their superior physical properties and ability to better replicate tendon tissue, the 3D electrospun scaffolds warrant greater investigation as synthetic grafts in tendon repair.


Assuntos
Regeneração Tecidual Guiada/instrumentação , Poliésteres/química , Traumatismos dos Tendões/cirurgia , Alicerces Teciduais , Animais , Bovinos , Eletroquímica/métodos , Análise de Falha de Equipamento , Regeneração Tecidual Guiada/métodos , Técnicas In Vitro , Teste de Materiais , Desenho de Prótese , Rotação , Traumatismos dos Tendões/patologia
13.
J Appl Clin Med Phys ; 14(4): 4163, 2013 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-23835382

RESUMO

Multimodality image registration plays a crucial role in various clinical and research applications. The aim of this study is to present an optimized MR to CT whole-body deformable image registration algorithm and its validation using clinical studies. A 3D intermodality registration technique based on B-spline transformation was performed using optimized parameters of the elastix package based on the Insight Toolkit (ITK) framework. Twenty-eight (17 male and 11 female) clinical studies were used in this work. The registration was evaluated using anatomical landmarks and segmented organs. In addition to 16 anatomical landmarks, three key organs (brain, lungs, and kidneys) and the entire body volume were segmented for evaluation. Several parameters--such as the Euclidean distance between anatomical landmarks, target overlap, Dice and Jaccard coefficients, false positives and false negatives, volume similarity, distance error, and Hausdorff distance--were calculated to quantify the quality of the registration algorithm. Dice coefficients for the majority of patients (> 75%) were in the 0.8-1 range for the whole body, brain, and lungs, which satisfies the criteria to achieve excellent alignment. On the other hand, for kidneys, Dice coefficients for volumes of 25% of the patients meet excellent volume agreement requirement, while the majority of patients satisfy good agreement criteria (> 0.6). For all patients, the distance error was in 0-10 mm range for all segmented organs. In summary, we optimized and evaluated the accuracy of an MR to CT deformable registration algorithm. The registered images constitute a useful 3D whole-body MR-CT atlas suitable for the development and evaluation of novel MR-guided attenuation correction procedures on hybrid PET-MR systems.


Assuntos
Interpretação de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Encéfalo/anatomia & histologia , Encéfalo/diagnóstico por imagem , Feminino , Humanos , Rim/anatomia & histologia , Rim/diagnóstico por imagem , Pulmão/anatomia & histologia , Pulmão/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Adulto Jovem
14.
J Microencapsul ; 30(7): 613-23, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23915304

RESUMO

Recently, it has been showed that gadolinium oxide nanoparticles can provide high-contrast enhancement in magnetic resonance imaging (MRI). Moreover, liposomes due to high biocompatibility have shown unique model systems, with the most successful application being the drug delivery system. As a suitable cell-tracking contrast agent (CA) in molecular MRI (mMRI), the synthesis and optimisation characteristic of a novel paramagnetic liposomes (PMLs) based on gadolinium nanoparticles, essentially composed of a new complex of gadolinium oxide-diethylene glycol (Gd2O3-DEG) loaded in liposomes have been determined in this research. Gd2O3-DEG was prepared by a new supervised polyol method and was encapsulated with liposome by the film hydration method. The paramagnetic liposome nanoparticle (PMLN) sizes ranged from 65 to 170 nm. The r1 of PMLNs and Gd2O3-DEG were much higher than that of Gd-diethylenetriamine penta-acetic acid (Gd-DTPA). In MC/9 cell lines, the experiments showed similar results as in water. PMLNs with lower T1 than Gd-DTPA are sensitive, positive MRI CA that could be attractive candidates for cellular and molecular lipid content targets such as diagnostic applications.


Assuntos
Meios de Contraste/administração & dosagem , Etilenoglicóis/administração & dosagem , Gadolínio/administração & dosagem , Lipossomos/química , Nanopartículas/química , Animais , Linhagem Celular , Meios de Contraste/análise , Etilenoglicóis/análise , Gadolínio/análise , Lipossomos/ultraestrutura , Imageamento por Ressonância Magnética/métodos , Camundongos , Nanopartículas/ultraestrutura
15.
Nat Genet ; 30(4): 406-10, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11865300

RESUMO

Uterine leiomyomata (fibroids) are common and clinically important tumors, but little is known about their etiology and pathogenesis. We previously mapped a gene that predisposes to multiple fibroids, cutaneous leiomyomata and renal cell carcinoma to chromosome 1q42.3-q43 (refs 4-6). Here we show, through a combination of mapping critical recombinants, identifying individuals with germline mutations and screening known and predicted transcripts, that this gene encodes fumarate hydratase, an enzyme of the tricarboxylic acid cycle. Leiomyomatosis-associated mutations are predicted to result in absent or truncated protein, or substitutions or deletions of highly conserved amino acids. Activity of fumarate hydratase is reduced in lymphoblastoid cells from individuals with leiomyomatosis. This enzyme acts as a tumor suppressor in familial leiomyomata, and its measured activity is very low or absent in tumors from individuals with leiomyomatosis. Mutations in FH also occur in the recessive condition fumarate hydratase deficiency, and some parents of people with this condition are susceptible to leiomyomata. Thus, heterozygous and homozygous or compound heterozygous mutants have very different clinical phenotypes. Our results provide clues to the pathogenesis of fibroids and emphasize the importance of mutations of housekeeping and mitochondrial proteins in the pathogenesis of common types of tumor.


Assuntos
Carcinoma Papilar/genética , Carcinoma de Células Renais/genética , Fumarato Hidratase/genética , Mutação em Linhagem Germinativa , Neoplasias Renais/genética , Leiomioma Epitelioide/genética , Leiomioma/genética , Neoplasias Uterinas/genética , Alelos , Cromossomos Humanos Par 1 , Éxons , Feminino , Fumarato Hidratase/metabolismo , Deleção de Genes , Genes Dominantes , Marcadores Genéticos , Humanos , Hibridização in Situ Fluorescente , Masculino , Mutação , Linhagem , Recombinação Genética , Análise de Sequência de DNA
16.
Mymensingh Med J ; 22(1): 15-9, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23416802

RESUMO

Geographical and socio-economic factors such as climate, culture, ethnic origin, diet and life style such as smoking have been noted to influence the occurrence of bronchial carcinoma. We conducted this study to document the frequency of various histological types of bronchial carcinoma and correlated it with their demographic characteristics. This descriptive study was carried out among admitted patient with the suspicion of Bronchial carcinoma from January 2010 to January 2011 in medicine units of Mymensingh Medical College Hospital, Mymensingh. Among those only 30 consecutive histopathologically &/or cytological confirmed cases of Bronchial carcinoma were included in the study. No age, gender, environmental or occupational limits were applied for the selection of patients. Patients already diagnosed by some other hospital presenting to our unit with complications were not included in the study. Age rang were 26-70 years. Majority of patients i.e. 63.33% (n=19) were found to be in their fourth and sixth decade of life. Males were 86.66% (n=26) as compared to females 13.44% (n=4) and male to female ratio were 6.5:1. The majority of the patients were belonged to urban areas 63.34% (n=19), while 36.66% (n=11) came from the Rural population. In this study smokers were 86.66% (n=26) and nonsmokers were 13.33% (n=4). In Occupational distribution farmers were 33.33% (n=10), service holders were 20% (n=6), businessman were 16.66% (n=5), all the female were house wife 13.33% (n=4). Specimens for histopathological study were collected by trans-thoracic needle aspiration under CT or ultrasono-guided. The results of cell types in histopathologically proven 30 Bronchial carcinoma patients were; 10(33.36%) adenocarcinoma, 7(23.33%) squamous cell carcinoma, 6(20%) small cell carcinoma, 4(13.33%) large cell carcinoma and 3(10%) non-small cell carcinoma.


Assuntos
Carcinoma Broncogênico/epidemiologia , Neoplasias Pulmonares/epidemiologia , Adenocarcinoma/epidemiologia , Adulto , Distribuição por Idade , Idoso , Bangladesh/epidemiologia , Carcinoma de Células Grandes/epidemiologia , Carcinoma de Células Grandes/patologia , Carcinoma Pulmonar de Células não Pequenas/epidemiologia , Carcinoma Pulmonar de Células não Pequenas/patologia , Carcinoma de Células Escamosas/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ocupações/estatística & dados numéricos , Estudos Prospectivos , População Rural/estatística & dados numéricos , Distribuição por Sexo , Carcinoma de Pequenas Células do Pulmão/epidemiologia , Fumar/epidemiologia , Centros de Atenção Terciária , População Urbana/estatística & dados numéricos
17.
Rural Remote Health ; 13(2): 2353, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23517439

RESUMO

INTRODUCTION: Tasmania is Australia's smallest state measuring approximately 68,000 km2 and separated (by approximately 240 km of ocean) from the mainland of Australia, at the south-east corner of the continent. The total resident population of Tasmania is approximately 500,000 people with the greatest population density in the capital city, Hobart. Adult dental care is subsidised for socioeconomically disadvantaged people and are provided through the State government dental clinics. Emergency demand for adult dental care is rationed through a triage system (mainly by telephone contact with trained receptionists), applied across the State based on universal clinically agreed criteria. The aim of this study was to analyse the outcomes of this triage system in delivering effective public emergency dental care services in Tasmania. METHODS: The study population consisted of all patients who approached the dental services in Tasmania for emergency care over a period of 3 years. The data were collected from all four major fixed public dental clinics for the calendar years 2009, 2010 and 2011. RESULTS: A total of 56,298 triage events were analysed over the 3 years (2009-2011) of the study. The proportion of each triage outcome category (ie speed to needing to be seen) was stable. Regarding month-to-month variation, December had the lowest overall number of events (n=3921) and August had the greatest (n=5237). There was a tendency mid-year (winter in the southern hemisphere) for triage events to be above the baseline, while in summer (December to February) there were fewer events. Most triage events occurred on the first day of the working week (Monday), and the least occurred on Fridays. Over half the events were driven from two patient symptom sets: (1) pain that woke patients at night; and (2) pain that required analgesics. CONCLUSION: In order to deal with the current workforce shortage and funding constraints in the public health sector, the peri-operative workforce such as receptionists can be utilized in innovative ways such as triage, and in particular clinical-based systematic telephone-based assistance.


Assuntos
Desenho Assistido por Computador , Serviços de Saúde Bucal , Tratamento de Emergência/normas , Serviços de Saúde Rural , Triagem/métodos , Adulto , Serviços de Saúde Bucal/organização & administração , Serviços de Saúde Bucal/provisão & distribuição , Humanos , Avaliação de Processos e Resultados em Cuidados de Saúde , Avaliação de Programas e Projetos de Saúde , Estudos Retrospectivos , Serviços de Saúde Rural/organização & administração , Tasmânia , Triagem/normas , Listas de Espera , Recursos Humanos
18.
Philos Trans R Soc Lond B Biol Sci ; 378(1868): 20210433, 2023 01 16.
Artigo em Inglês | MEDLINE | ID: mdl-36440563

RESUMO

Across human societies, women's economic production and their contributions to childcare are critical in supporting reproductive fitness for themselves, their spouses and children. Yet, the necessity of performing both work and childcare tasks presents women with an adaptive problem in which they must determine how best to allocate their time and energy between these tasks. Women often use cooperative relationships with alloparents to solve this problem, but whether or not women cooperate across different domains (e.g. work and childcare) to access alloparents remains relatively under-explored. Using social network data collected with Shodagor households in Bangladesh, we show that women who need childcare help in order to work draw on cooperative work partners as potential alloparents, and that all women rely heavily on kin, but not reciprocal cooperation for childcare help. These results indicate that Shodagor women strategize to create work and childcare relationships in ways that help solve the adaptive problem they face. We discuss the implications of our results and the example provided by Shodagor women for a broader understanding of women's cooperative relationships, including the importance of socio-ecological circumstances and gendered divisions of labour in shaping women's cooperative strategies. This article is part of the theme issue 'Cooperation among women: evolutionary and cross-cultural perspectives'.


Assuntos
Cuidado da Criança , Saúde da Criança , Criança , Humanos , Características da Família , Cônjuges , Identidade de Gênero
19.
Clin Neurophysiol ; 146: 30-39, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36525893

RESUMO

OBJECTIVE: Distinguishing major depressive disorder (MDD) from bipolar disorder (BD) is a crucial clinical challenge as effective treatment is quite different for each condition. In this study electroencephalography (EEG) was explored as an objective biomarker for distinguishing MDD from BD using an efficient machine learning algorithm (MLA) trained by a relatively large and balanced dataset. METHODS: A 3 step MLA was applied: (1) a multi-step preprocessing method was used to improve the quality of the EEG signal, (2) symbolic transfer entropy (STE), an effective connectivity measure, was applied to the resultant EEG and (3) the MLA used the extracted STE features to distinguish MDD (N = 71) from BD (N = 71) subjects. RESULTS: 14 connectivity features were selected by the proposed algorithm. Most of the selected features were related to the frontal, parietal, and temporal lobe electrodes. The major involved regions were the Broca region in the frontal lobe and the somatosensory association cortex in the parietal lobe. These regions are near electrodes FC5 and CPz and are involved in processing language and sensory information, respectively. The resulting classifier delivered an evaluation accuracy of 88.5% and a test accuracy of 89.3%, using 80% of the data for training and evaluation and the remaining 20% for testing, respectively. CONCLUSIONS: The high evaluation and test accuracies of our algorithm, derived from a large balanced training sample suggests that this method may hold significant promise as a clinical tool. SIGNIFICANCE: The proposed MLA may provide an inexpensive and readily available tool that clinicians may use to enhance diagnostic accuracy and shorten time to effective treatment.


Assuntos
Transtorno Bipolar , Transtorno Depressivo Maior , Humanos , Transtorno Depressivo Maior/diagnóstico , Transtorno Depressivo Maior/terapia , Transtorno Bipolar/diagnóstico , Aprendizado de Máquina , Lobo Frontal , Eletroencefalografia/métodos
20.
Evol Hum Sci ; 5: e5, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37587939

RESUMO

Success in marriage markets has lasting impacts on women's wellbeing. By arranging marriages, parents exert financial and social powers to influence spouse characteristics and ensure optimal marriages. While arranging marriages is a major focus of parental investment, marriage decisions are also a source of conflict between parents and daughters in which parents often have more power. The process of market integration may alter parental investment strategies, however, increasing children's bargaining power and reducing parents' influence over children's marriage decisions. We use data from a market integrating region of Bangladesh to (a) describe temporal changes in marriage types, (b) identify which women enter arranged marriages and (c) determine how market integration affects patterns of arranged marriage. Most women's marriages were arranged, with love marriages more recent. We found few predictors of who entered arranged vs. love marriages, and family-level market integration did not predict marriage type at the individual level. However, based on descriptive findings, and findings relating women's and fathers' education to groom characteristics, we argue that at the society-level market integration has opened a novel path in which daughters use their own status, gained via parental investments, to facilitate good marriages under conditions of reduced parental assistance or control.

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