1.
Science
; 160(3823): 81-2, 1968 Apr 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5689266
RESUMO
Incubation of deamino-oxytocin with plasma obtained from women in labor reduced the potency of this analog of oxytocin when assayed on an isolated strip of mammary gland taken from a lactating rat. Plasmas of nonpregnant women had no detectable effect on this activity of deamino-oxytocin, and the effect of plasmas from women just previous to the beginning of labor was not significant. The original. activities of the incubated deamino-oxytocin solutions could be restored by treatment with hydrogen peroxide. The inactivation may be caused by reductive cleavage of the disulfide bridge of deamino-oxytocin, this bridge being reformed by oxidation.
Assuntos
Sangue , Ocitócicos/análise , Ocitocina , Animais , Bioensaio , Feminino , Humanos , Peróxido de Hidrogênio , Técnicas In Vitro , Trabalho de Parto , Lactação , Glândulas Mamárias Animais/efeitos dos fármacos , Gravidez , Ratos , Sulfetos
2.
Am J Obstet Gynecol
; 119(5): 596-602, 1974 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4857791
3.
An Fac Med Univ Repub Montev Urug
; 51(1): 56-62, 1966.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-6015092