Detalhe da pesquisa
1.
Structure-Guided Optimization Provides a Series of TTK Protein Inhibitors with Potent Antitumor Activity.
J Med Chem
; 64(17): 12670-12679, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34459599
2.
Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
J Med Chem
; 64(16): 11886-11903, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355886
3.
Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy.
J Med Chem
; 62(9): 4401-4410, 2019 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998356
4.
The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.
J Med Chem
; 60(21): 8989-9002, 2017 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28991472