Detalhe da pesquisa
1.
Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Nature
; 583(7817): 620-624, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669709
2.
Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis.
Blood
; 141(21): 2615-2628, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36735903
3.
Carfilzomib induction, consolidation, and maintenance with or without autologous stem-cell transplantation in patients with newly diagnosed multiple myeloma: pre-planned cytogenetic subgroup analysis of the randomised, phase 2 FORTE trial.
Lancet Oncol
; 24(1): 64-76, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528035
4.
Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells.
Int J Mol Sci
; 24(7)2023 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047732
5.
Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies.
Molecules
; 28(4)2023 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36838885
6.
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment.
Haematologica
; 107(6): 1410-1426, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34670358
7.
Carfilzomib with cyclophosphamide and dexamethasone or lenalidomide and dexamethasone plus autologous transplantation or carfilzomib plus lenalidomide and dexamethasone, followed by maintenance with carfilzomib plus lenalidomide or lenalidomide alone for patients with newly diagnosed multiple myeloma (FORTE): a randomised, open-label, phase 2 trial.
Lancet Oncol
; 22(12): 1705-1720, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34774221
8.
A real-world efficacy and safety analysis of combined carfilzomib, lenalidomide, and dexamethasone (KRd) in relapsed/refractory multiple myeloma.
Hematol Oncol
; 39(1): 41-50, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085797
9.
Pre-transplant minimal residual disease assessment and transplant-related factors predict the outcome of acute myeloid leukemia patients undergoing allogeneic stem cell transplantation.
Eur J Haematol
; 107(5): 573-582, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297437
10.
Author Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Nature
; 588(7839): E33, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33273708
11.
The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs.
Haematologica
; 105(10): 2420-2431, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054082
12.
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
FASEB J
; 33(3): 3704-3717, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514106
13.
Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Blood
; 129(16): 2233-2245, 2017 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096095
14.
APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.
Blood
; 127(25): 3225-36, 2016 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27127303
15.
Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells.
Blood
; 127(9): 1138-50, 2016 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26675349
16.
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.
Haematologica
; 103(1): 80-90, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29025907
17.
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model.
FASEB J
; 31(7): 3138-3149, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28386046
18.
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
Bioorg Med Chem
; 25(20): 5849-5858, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28958848
19.
Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma.
Blood
; 123(20): 3128-38, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569262
20.
Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis.
Mediators Inflamm
; 2016: 9153673, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738391