[Uretero-intestinal anastomosis using the ureteral nipple technique with personal modification in continent urinary diversion]. / Anastomosi uretero intestinale secondo la tecnica del nipple ureterale con modifica personale nelle derivazioni urinarie continenti.

BACKGROUND: This report presents the follow-up data for the incidence of stenosis and reflux in 143 split cuff nipple ureteral intestinal anastomoses in continent urinary diversions. METHODS: 74 ureteral implants (1990-1995) were performed using the original technique, whereas a technical modification was adopted after 1996. This was used in 69 implants and consisted of the removal of a button of bowel tract in order to obtain a linear implant to the reservoir, instead of using a simple enterotomy at the level of the anastomosis. RESULTS: The rate of clinically significant refluxes was 2.2%, whereas the incidence of stenosis fell from 6.8% in the group using the original technique to 2.9% in those using the modified technique. CONCLUSIONS: Anastomosis using the split cuff ureteral nipple technique is simple to perform and is indicated in peristaltic and non-dilatated ureters. Moreover, this technical modification improves the overall results.

[A case of Leydig cell tumor of the testis]. / Su di un caso di tumore del testicolo a cellule di Leydig.

Leydig cell tumors represent about 3% of all testicular neoplasms. Actually no specific pathologic criteria has really distinguished the benign from the malignant tumors which represent about 11% of the cases. The presence of metastases is the only unequivocal criteria of malignancy. Authors present a rare Leydigoma case with gynecomastia. Clinical, diagnostical and most of all therapeutical aspects are discussed reconfirming the role of the orchifuniculectomy in T1 N0 M0 stage.

[Adjuvant chemotherapy in infiltrating bladder carcinoma. Long-term results]. / La chemioterapia adiuvante nel carcinoma vescicale infiltrante. Risultati a distanza.

The authors present the long-term of adjuvant chemotherapy using M-VEC scheme (Mtx 20 mg/mq; vinblastine 0.1 mg/kg; CDDP 40 mg/mq; epirubicin 30 mg/mq each 21 day for six cycles) effected in 28 patients (21 males and 7 women with average age of 67) undergone radical cystectomy for invasive bladder carcinoma p G2-3 T-4 N + M0. Total survival after 5 years was 28.6% while disease-free survival is 18.8%; in 71.3% there are been clinical progression and the mortality to 5 years was 62%.

[Benign multilocular cystic nephroma. Description of 1 case]. / Nefroma cistico multiloculare benigno. Descrizione di un caso.

The case of a multiple kidney cyst in an adult patient is described. The cyst had caused parenchymal atrophy by blocking the excretory ways. The pathological anatomy of the lesion is described and the aetiopathogenic hypotheses found in the literature are reported.

[Adjuvant therapy with vinblastine and interferon in metastatic renal carcinoma]. / La terapia adiuvante con VBL + IFN nel carcinoma renale metastatico.

An integrated therapeutic approach was adopted to treat metastatic renal carcinoma, the reason being: 1) to effect a regression of metastasis that could not be attacked surgically either because of its location or extent; 2) to limit micrometastatic diffusion in patients with N+.0.05 mg/kg Vinblastine was used every three weeks in association with alfa-2A-IFN in a dose of 18 X 10(6) U 3 times a week. Included in this study were twelve patients with renal carcinoma subjected to nephrectomy with lymph nodal metastases and with or without remote M+. Without drawing hasty conclusions, this therapy can be said to have a useful role after correct surgical approach.

[Urotheliomas of the upper excretory tract. Analysis and results after 10 years]. / Gli uroteliomi dell'alta via escretrice. Analisi e risultati dopo dieci anni.

The recent introduction of endourology and accumulated experience has led to the development of concepts regarding the effective role of conservative surgical treatment in cancer of the upper urinary tract. The Authors report their experience in 59 patients with cancer of the upper urinary tract; 36 (61.2%) underwent radical surgery whereas 23 (38.9%) were treated using conservative surgical therapy. The results of this retrospective study confirm the role of conservative surgical therapy in cases at an initial stage of cancer development, together with an attentive endourological follow-up.

[Asymptomatic, right reno-ureteral calculi in a cake kidney]. / Calcolosi reno-ureterale destra asintomatica in "rene a focaccia".

The primary caudal site of the urogenital anlage in the embryo explains why certain positional anomalies occur during cranial migration and are the outcome of various associated factors. A case of ectopic fusion in the ileo-sacral site known as cake kidney whose peculiarity consists of totally asymptomatic right multiple reno-ureteral lithiasis identified by chance is reported.

[Intracavernous pharmacotherapy in men who have undergone cystectomy for neoplasia]. / Farmacoterapia intracavernosa nei cistectomizzati per neoplasia.

Impotentia erigendi is a consequence of radical surgery such as cystectomy due to neoplasia. It is caused by damage to neurovascular structures, and in particular to the nerve fibres of the sacral plexus. Current therapies include the use of penile prostheses or drug therapy. The paper reports the Authors' personal experience of the use of intracavernous drug therapy in 24 patients cystectomised due to vesical carcinoma. Objectively valid results were obtained in 33% of patients. No complications were observed and the treatment represents a valid alternative to mechanical prosthesis.

[Pharmacologic treatment of benign prostatic hypertrophy (BPH): a combination of mepartricin and simvastatin. Analysis and results]. / Un razionale farmacologico per l'ipertrofia prostatica benigna (IPB): associazione di mepartricina e simvastatina. Analisi e risultati.

The Authors propose a medical treatment for Benign Prostatic Hyperplasia (BPH) using mepartricina-simvastatina, two drugs with a hypocholesterolemizing action. We have treated fifty patients with BPH (twelve with permanent catheters) obtaining a complete clinical results in 40% of the total and a partial clinical result in 38%. This therapy, in association with a correct diet and adequate physical activity, significantly improved not only the cervicurethral obstruction but also general hematochemical and, above all, lipidemic parameters.

[Diet therapy in the prevention of renal calculosis]. / La terapia dietetica nella profilassi della calcolosi renale.

The importance of diet within the framework of effective therapeutic measures in the prophylaxis of recurring lithiasis is emphasised. Some diet sheets are presented.

[Adjuvant chemo-immunotherapy with VBL + INF in renal carcinoma. Long-term results]. / Chemioimmunoterapia adiuvante con VBL + INF nel Ca Renale. Risultati a distanza.

Authors show results of adjuvant chemoimmunotherapeutic approach (0, 10 mg/kg Vinblastine every three weeks plus INF - alpha 2a - and INF - alpha 2b in a dose of 3 x 10(6) U.I. three times a week) adopted after radical nephrectomy in 45 patients with renal carcinoma (p. T3/4. NO.MO; pT3/4. N+/O. M+/O). The treatment may be summed up: 1# to effect a regression of metastasis that is not possible surgically to remove either because of its location or extent; 2) to limit micrometastatic diffusion in patients with N+. 3) It is important to perform this treatment in stage T3 N0M0 where clinical progression is (21.1%) in our group.