RESUMO
Over the last decade there has been an explosion of endoscopic surgical procedures that is now having profound effects on training in gynaecology. As trainees adopt these new procedures, they should obtain formal training supplemented by appropriate senior supervision which has been shown to reduce the risk of iatrogenic endoscopic complications.
Assuntos
Educação Médica Continuada , Endoscopia , Cirurgia Geral/educação , Procedimentos Cirúrgicos em Ginecologia , Feminino , HumanosRESUMO
The efficacy of and tolerance to fancimef in 49 patients was compared to the efficacy of and tolerance to quinine in combination with fansidar in 33 patients with moderate P. falciparum malaria. A good tolerance to and a high efficacy of fancimef have been shown, which was manifested in rapid fever arrest, disappearance of parasitemia, absence of the disease relapses, which were observed in 2 patients on quinine combined with fansidar. The advantage of fansimef is one-time administration of the total course dose.
Assuntos
Antimaláricos/uso terapêutico , Malária/tratamento farmacológico , Mefloquina/análogos & derivados , Plasmodium falciparum , Pirimetamina/uso terapêutico , Sulfadoxina/uso terapêutico , Doença Aguda , Adolescente , Adulto , Animais , Criança , Combinação de Medicamentos , Resistência a Medicamentos , Tolerância a Medicamentos , Feminino , Humanos , Malária/sangue , Malária/parasitologia , Masculino , Mefloquina/uso terapêutico , Pessoa de Meia-Idade , VietnãRESUMO
The study was performed in the area of distribution of tropical malaria resistant to 4-aminoquinolines (Vietnam) on 30 patients receiving lariam (mefloquine). The results were compared to the standard therapy with quinine and fansidar. They indicate a high efficacy of and a good tolerance to the drug tested. The use of lariam leads to a more rapid (as compared to the standard treatment) elimination of parasitemia and complete eradication of the disease relapses. The findings make it possible to recommend lariam for the prevention and treatment of tropical malaria.
Assuntos
Malária/tratamento farmacológico , Mefloquina/uso terapêutico , Plasmodium falciparum , Adolescente , Adulto , Animais , Antimaláricos/uso terapêutico , Combinação de Medicamentos , Resistência a Medicamentos , Quimioterapia Combinada , Tolerância a Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pirimetamina/uso terapêutico , Quinina/uso terapêutico , Sulfadoxina/uso terapêutico , VietnãAssuntos
Vacinas contra Papillomavirus/uso terapêutico , Neoplasias do Colo do Útero/prevenção & controle , Anticorpos Antineoplásicos/efeitos dos fármacos , Formação de Anticorpos/efeitos dos fármacos , Feminino , Humanos , Vacinas contra Papillomavirus/normas , Lesões Pré-Cancerosas/imunologia , Lesões Pré-Cancerosas/patologia , Lesões Pré-Cancerosas/prevenção & controle , Ensaios Clínicos Controlados Aleatórios como Assunto , Neoplasias do Colo do Útero/imunologia , Neoplasias do Colo do Útero/patologiaAssuntos
Membrana Eritrocítica/fisiopatologia , Hemólise , Malária/sangue , Adolescente , Adulto , Antimaláricos/efeitos adversos , Antimaláricos/uso terapêutico , Membrana Eritrocítica/efeitos dos fármacos , Hemólise/efeitos dos fármacos , Humanos , Malária/tratamento farmacológico , Pessoa de Meia-IdadeRESUMO
The case records of four patients with scleroderma who booked for care between 1989 and 1994 at the Birmingham Women's Hospital (formerly the Birmingham Maternity Hospital), a tertiary care obstetric unit, were studied retrospectively. The aim of the study was to look at infertility, early and late pregnancy losses, fetal growth retardation and maternal complications in these four women afflicted with this rare condition. Two patients gave a history of infertility. There were two growth retarded fetuses and one intrauterine fetal death. Worsening Raynaud's phenomenon occurred in three patients. Another patient developed massive haematemesis due to an oesophageal tear resulting from intractable vomiting. Scleroderma may adversely affect pregnancy: obstetrical complications are common and require close monitoring.