Pesquisa | BVS Educação Profissional em Saúde

1.

Systemic anticancer therapy for urothelial carcinoma: UK oncologists' perspective.

Jones, Robert J; Crabb, Simon J; Linch, Mark; Birtle, Alison J; McGrane, John; Enting, Deborah; Stevenson, Robert; Liu, Kin; Kularatne, Bihani; Hussain, Syed A.

Br J Cancer ; 130(6): 897-907, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38191608

2.

Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study.

Massari, Francesco; Santoni, Matteo; Takeshita, Hideki; Okada, Yohei; Tapia, Jose Carlos; Basso, Umberto; Maruzzo, Marco; Scagliarini, Sarah; Büttner, Thomas; Fornarini, Giuseppe; Myint, Zin W; Galli, Luca; Souza, Vinicius Carrera; Pichler, Renate; De Giorgi, Ugo; Gandur, Nathalia; Lam, Elaine T; Gilbert, Danielle; Popovic, Lazar; Grande, Enrique; Mammone, Giulia; Berardi, Rossana; Crabb, Simon J; Kemp, Robert; Molina-Cerrillo, Javier; Freitas, Marcelo; Luz, Murilo; Iacovelli, Roberto; Calabrò, Fabio; Tural, Deniz; Atzori, Francesco; Küronya, Zsófia; Chiari, Rita; Campos, Saul; Caffo, Orazio; Fay, André P; Kucharz, Jakub; Zucali, Paolo Andrea; Rinck, José Augusto; Zeppellini, Annalisa; Bastos, Diogo Assed; Aurilio, Gaetano; Mota, Augusto; Trindade, Karine; Ortega, Cinzia; Sade, Juan Pablo; Rizzo, Mimma; Fiala, Ondrej; Vau, Nuno; Giannatempo, Patrizia.

Cancer Immunol Immunother ; 73(6): 106, 2024 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-38634928

3.

Real-world effectiveness of pembrolizumab as first-line therapy for cisplatin-ineligible patients with advanced urothelial carcinoma: the ARON-2 study.

Santoni, Matteo; Myint, Zin W; Büttner, Thomas; Takeshita, Hideki; Okada, Yohei; Lam, Elaine T; Gilbert, Danielle; Küronya, Zsófia; Tural, Deniz; Pichler, Renate; Grande, Enrique; Crabb, Simon J; Kemp, Robert; Massari, Francesco; Scagliarini, Sarah; Iacovelli, Roberto; Vau, Nuno; Basso, Umberto; Maruzzo, Marco; Molina-Cerrillo, Javier; Galli, Luca; Bamias, Aristotelis; De Giorgi, Ugo; Zucali, Paolo Andrea; Rizzo, Mimma; Seront, Emmanuel; Popovic, Lazar; Caffo, Orazio; Buti, Sebastiano; Kanesvaran, Ravindran; Kopecky, Jindrich; Kucharz, Jakub; Zeppellini, Annalisa; Fiala, Ondrej; Landmesser, Johannes; Ansari, Jawaher; Giannatempo, Patrizia; Rizzo, Alessandro; Zabalza, Ignacio Ortego; Monteiro, Fernando Sabino M; Battelli, Nicola; Calabrò, Fabio; Porta, Camillo.

Cancer Immunol Immunother ; 72(9): 2961-2970, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37248424

4.

Use of concomitant proton pump inhibitors, statins or metformin in patients treated with pembrolizumab for metastatic urothelial carcinoma: data from the ARON-2 retrospective study.

Fiala, Ondrej; Buti, Sebastiano; Takeshita, Hideki; Okada, Yohei; Massari, Francesco; Palacios, Georgia Anguera; Dionese, Michele; Scagliarini, Sarah; Büttner, Thomas; Fornarini, Giuseppe; Myint, Zin W; Galli, Luca; Souza, Vinicius Carrera; Pichler, Renate; De Giorgi, Ugo; Quiroga, María Natalia Gandur; Gilbert, Danielle; Popovic, Lazar; Grande, Enrique; Mammone, Giulia; Berardi, Rossana; Crabb, Simon J; Molina-Cerrillo, Javier; Freitas, Marcelo; Luz, Murilo; Iacovelli, Roberto; Calabrò, Fabio; Tural, Deniz; Atzori, Francesco; Küronya, Zsófia; Chiari, Rita; Campos, Saul; Caffo, Orazio; Fay, André P; Kucharz, Jakub; Zucali, Paolo Andrea; Rinck, José Augusto; Zeppellini, Annalisa; Bastos, Diogo Assed; Aurilio, Gaetano; Mota, Augusto; Trindade, Karine; Ortega, Cinzia; Sade, Juan Pablo; Rizzo, Mimma; Vau, Nuno; Giannatempo, Patrizia; Barillas, Allan; Monteiro, Fernando Sabino Marques; Dauster, Breno.

Cancer Immunol Immunother ; 72(11): 3665-3682, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37676282

5.

Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE): a double-blind, randomised, phase 2 trial.

Hussain, Syed A; Lester, Jason F; Jackson, Richard; Gornall, Matthew; Qureshi, Muneeb; Elliott, Anthony; Crabb, Simon J; Huddart, Robert A; Vasudev, Naveen; Birtle, Alison J; Worlding, Jane; James, Nicholas D; Parikh, Omi; Vilarino-Varela, Maria; Alonzi, Roberto; Linch, Mark D; Riaz, Irbaz B; Catto, James W F; Powles, Thomas; Jones, Robert J.

Lancet Oncol ; 23(5): 650-658, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35421369

6.

Efficacy of Platinum Rechallenge in Metastatic Urothelial Carcinoma After Previous Platinum-Based Chemotherapy for Metastatic Disease.

Wong, Risa L; Ferris, Lorin A; Do, Olivia A; Holt, Sarah K; Ramos, Jorge D; Crabb, Simon J; Sternberg, Cora N; Bellmunt, Joaquim; Ladoire, Sylvain; De Giorgi, Ugo; Harshman, Lauren C; Vaishampayan, Ulka N; Necchi, Andrea; Srinivas, Sandy; Pal, Sumanta K; Niegisch, Guenter; Dorff, Tanya B; Galsky, Matthew D; Yu, Evan Y.

Oncologist ; 26(12): 1026-1034, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34355457

7.

Tumor downstaging as an intermediate endpoint to assess the activity of neoadjuvant systemic therapy in patients with muscle-invasive bladder cancer.

Martini, Alberto; Jia, Rachel; Ferket, Bart S; Waingankar, Nikhil; Plimack, Elizabeth R; Crabb, Simon J; Harshman, Lauren C; Yu, Evan Y; Powles, Thomas; Rosenberg, Jonathan E; Pal, Sumanta K; Vaishampayan, Ulka N; Necchi, Andrea; Wiklund, N Peter; Mehrazin, Reza; Mazumdar, Madhu; Sfakianos, John P; Galsky, Matthew D.

Cancer ; 125(18): 3155-3163, 2019 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-31150110

8.

The latest treatment options for bladder cancer.

Crabb, Simon J; Douglas, James.

Br Med Bull ; 128(1): 85-95, 2018 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-30371744

9.

Impact of the Number of Cycles of Platinum Based First Line Chemotherapy for Advanced Urothelial Carcinoma.

Sonpavde, Guru P; Mariani, Luigi; Lo Vullo, Salvatore; Raggi, Daniele; Giannatempo, Patrizia; Bamias, Aristotle; Crabb, Simon J; Bellmunt, Joaquim; Yu, Evan Y; Niegisch, Guenter; Vaishampayan, Ulka N; Theodore, Christine; Berthold, Dominik R; Srinivas, Sandy; Sridhar, Srikala S; Plimack, Elizabeth R; Rosenberg, Jonathan E; Powles, Thomas; Galsky, Matthew D; Necchi, Andrea.

J Urol ; 200(6): 1207-1214, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30012366

10.

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models.

Regufe da Mota, Sergio; Bailey, Sarah; Strivens, Rosemary A; Hayden, Annette L; Douglas, Leon R; Duriez, Patrick J; Borrello, M Teresa; Benelkebir, Hanae; Ganesan, A; Packham, Graham; Crabb, Simon J.

Cancer Cell Int ; 18: 71, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29760584

11.

Radical cystectomy or bladder preservation with radiochemotherapy in elderly patients with muscle-invasive bladder cancer: Retrospective International Study of Cancers of the Urothelial Tract (RISC) Investigators.

Boustani, Jihane; Bertaut, Aurélie; Galsky, Matthew D; Rosenberg, Jonathan E; Bellmunt, Joaquim; Powles, Thomas; Recine, Federica; Harshman, Lauren C; Chowdhury, Simon; Niegisch, Guenter; Yu, Evan Y; Pal, Sumanta K; De Giorgi, Ugo; Crabb, Simon J; Caubet, Matthieu; Balssa, Loïc; Milowsky, Matthew I; Ladoire, Sylvain; Créhange, Gilles.

Acta Oncol ; 57(4): 491-497, 2018 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-28853615

12.

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer.

Crabb, Simon J; Birtle, Alison J; Martin, Karen; Downs, Nichola; Ratcliffe, Ian; Maishman, Tom; Ellis, Mary; Griffiths, Gareth; Thompson, Stuart; Ksiazek, Lidia; Khoo, Vincent; Jones, Robert J.

Invest New Drugs ; 35(5): 599-607, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28144789

13.

IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial.

Rini, Brian I; Stenzl, Arnulf; Zdrojowy, Romauld; Kogan, Mikhail; Shkolnik, Mikhail; Oudard, Stephane; Weikert, Steffen; Bracarda, Sergio; Crabb, Simon J; Bedke, Jens; Ludwig, Joerg; Maurer, Dominik; Mendrzyk, Regina; Wagner, Claudia; Mahr, Andrea; Fritsche, Jens; Weinschenk, Toni; Walter, Steffen; Kirner, Alexandra; Singh-Jasuja, Harpreet; Reinhardt, Carsten; Eisen, Tim.

Lancet Oncol ; 17(11): 1599-1611, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-27720136

14.

Orteronel Switch Maintenance Therapy in Metastatic Castration Resistant Prostate Cancer After First-Line Docetaxel: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial (SAKK 08/11).

Cathomas, Richard; Crabb, Simon J; Mark, Michael; Winterhalder, Ralph; Rothermundt, Christian; Elliott, Tony; von Burg, Philippe; Kenner, Heike; Hayoz, Stefanie; Vilei, Simona Berardi; Rauch, Daniel; Roggero, Enrico; Mohaupt, Markus G; Bernhard, Jürg; Manetsch, Gabriela; Gillessen, Silke.

Prostate ; 76(16): 1519-1527, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27457964

15.

Treatment of upper urinary tract urothelial carcinoma.

Crabb, Simon J.

Lancet ; 395(10232): 1232-1234, 2020 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-32145828

16.

Loss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle-invasive bladder cancer.

Gurung, Pratik M S; Veerakumarasivam, Abhi; Williamson, Magali; Counsell, Nicholas; Douglas, James; Tan, Wei S; Feber, Andrew; Crabb, Simon J; Short, Susan C; Freeman, Alex; Powles, Thomas; Hoskin, Peter J; West, Catharine M; Kelly, John D.

Int J Cancer ; 136(3): 709-20, 2015 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-24917520

17.

Comparative effectiveness of gemcitabine plus cisplatin versus methotrexate, vinblastine, doxorubicin, plus cisplatin as neoadjuvant therapy for muscle-invasive bladder cancer.

Galsky, Matthew D; Pal, Sumanta K; Chowdhury, Simon; Harshman, Lauren C; Crabb, Simon J; Wong, Yu-Ning; Yu, Evan Y; Powles, Thomas; Moshier, Erin L; Ladoire, Sylvain; Hussain, Syed A; Agarwal, Neeraj; Vaishampayan, Ulka N; Recine, Federica; Berthold, Dominik; Necchi, Andrea; Theodore, Christine; Milowsky, Matthew I; Bellmunt, Joaquim; Rosenberg, Jonathan E.

Cancer ; 121(15): 2586-93, 2015 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-25872978

18.

High neutrophil-to-lymphocyte ratio persistent during first-line chemotherapy predicts poor clinical outcome in patients with advanced urothelial cancer.

Rossi, Lorena; Santoni, Matteo; Crabb, Simon J; Scarpi, Emanuela; Burattini, Luciano; Chau, Caroline; Bianchi, Emanuela; Savini, Agnese; Burgio, Salvatore L; Conti, Alessandro; Conteduca, Vincenza; Cascinu, Stefano; De Giorgi, Ugo.

Ann Surg Oncol ; 22(4): 1377-84, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25234022

19.

Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.

Pienta, Kenneth J; Machiels, Jean-Pascal; Schrijvers, Dirk; Alekseev, Boris; Shkolnik, Mikhail; Crabb, Simon J; Li, Susan; Seetharam, Shobha; Puchalski, Thomas A; Takimoto, Chris; Elsayed, Yusri; Dawkins, Fitzroy; de Bono, Johann S.

Invest New Drugs ; 31(3): 760-8, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22907596

20.

Systemic Treatment-Decision Algorithms in Muscle-Invasive Bladder Cancer: Clinical Complexities and Navigating for Improved Outcomes.

Giles, Megan; Crabb, Simon J.

Res Rep Urol ; 15: 321-331, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37441525

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