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1.
Anaesthesist ; 64 Suppl 1: 27-40, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26727936

RESUMO

Since the publication of the first German guidelines on airway management in 2004 new techniques have been established in the clinical routine and new insights into existing strategies have been published. As a consequence the new guidelines on airway management of the German Society of Anesthesiology and Intensive Care Medicine represent the current state of scientific knowledge and integrate the currently recommended techniques and strategies. The aim of these guidelines is to guarantee an optimal care of patients undergoing anesthesiological procedures and serve as an orientation and decision aid for users.


Assuntos
Manuseio das Vias Aéreas/normas , Extubação , Manuseio das Vias Aéreas/métodos , Anestesia , Anestesiologia/normas , Cuidados Críticos/normas , Alemanha , Fidelidade a Diretrizes , Humanos , Intubação Intratraqueal
2.
Anaesthesist ; 64(11): 859-73, 2015 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-26519189

RESUMO

Since the publication of the first german guidelines on airway management in 2014, new techniques have been established in the clinical routine and new insights into existing strategies have been published. As a consequence the new guidelines on airway management of the German Society of Anesthesiology and Intensive Care Medicine represent the current state of scientific knowledge and integrate the currently recommended techniques and strategies. The aim of these guidelines is to guarantee an optimal care of patients undergoing anesthesiological procedures and serve as an orientation and decision aid for users.


Assuntos
Manuseio das Vias Aéreas/normas , Anestesiologia/normas , Extubação/efeitos adversos , Extubação/normas , Manuseio das Vias Aéreas/efeitos adversos , Algoritmos , Anestesia/normas , Humanos , Máscaras Laríngeas , Valor Preditivo dos Testes
3.
Anaesthesiologie ; 2024 May 16.
Artigo em Inglês | MEDLINE | ID: mdl-38753159

RESUMO

The German airway management guidelines are intended to serve as an orientation and decision-making aid and thus contribute to the optimal care of patients undergoing anesthesiologic- and intensive medical care. As part of the pre-anesthesiologic evaluation, anatomical and physiological indications for difficult mask ventilation and intubation shall be evaluated. This includes the assessment of mouth opening, dental status, mandibular protrusion, cervical spine mobility and existing pathologies. The airway shall be secured while maintaining spontaneous breathing if there are predictors or anamnestic indications of difficult or impossible mask ventilation and/or endotracheal intubation. Various techniques can be used here. If there is an unexpectedly difficult airway, a video laryngoscope is recommended after unsuccessful direct laryngoscopy, consequently a video laryngoscope must be available at every anesthesiology workplace. The airway shall primarily be secured with a video laryngoscope in critically ill- and patients at risk of aspiration. Securing the airway using translaryngeal and transtracheal techniques is the "ultima ratio" in airway management. The performance or supervision of airway management in the intensive care unit is the responsibility of experienced physicians and nursing staff. Appropriate education and regular training are essential. Clear communication and interaction between team members are mandatory before every airway management procedure. Once the airway has been secured, the correct position of the endotracheal tube must be verified using capnography.

5.
Anaesthesist ; 61(7): 618-24, 2012 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-22699223

RESUMO

The Central Command for Maritime Emergencies was founded in Germany in 2003 triggered by the fire on board of the cargo ship "Pallas" in 1998. Its mission is to coordinate and direct measures at or above state level in maritime emergency situations in the North Sea and the Baltic Sea. A special task in this case is to provide firefighting and medical care. To face these challenges at sea emergency doctors and firemen have been specially trained. This form of organization provides a concept to counter mass casualty incidents and peril situations at sea. Since the foundation of the Central Command for Maritime Emergencies there have been 5 operations for firefighting units and 4 for medical response teams. Assignments and structure of the Central Command for Maritime Emergencies are unique in Europe.


Assuntos
Serviços Médicos de Emergência/tendências , Incidentes com Feridos em Massa , Navios/estatística & dados numéricos , Planejamento em Desastres/organização & administração , Tratamento Farmacológico , Serviços Médicos de Emergência/normas , Bombeiros , Incêndios , Alemanha , Equipe de Respostas Rápidas de Hospitais , Humanos
8.
Resuscitation ; 43(3): 195-9, 2000 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-10711488

RESUMO

The European Resuscitation Council has recommended smaller tidal volumes of 500 ml during basic life support ventilation in order to minimise gastric inflation. One method of delivering these tidal volumes may be to use paediatric instead of adult self-inflatable bags; however, we have demonstrated in other studies that only 350 ml may be delivered, using this technique. The reduced risk of gastric inflation was offset by oxygenation problems, rendering the strategy of attempting to deliver tidal volumes of 500 ml with a paediatric self-inflatable bag questionable, at least when using room-air. In this report, we assessed the effects of a self-inflatable bag with a size between the maximum size of a paediatric (700 ml) and an adult (1500 ml) self-inflatable bag on respiratory variables and blood gases during bag-valve-mask ventilation. After induction of anaesthesia, 50 patients were block-randomised into two groups of 25 each. They were ventilated with room-air with either an adult (maximum volume, 1500 ml) or a newly developed medium-size (maximum volume, 1100 ml; Dräger, Lübeck, Germany) self-inflatable bag for 5 min before intubation. When compared with the adult self-inflatable bag, the medium-size bag resulted in significantly lower exhaled tidal volumes and tidal volumes per kg bodyweight (624 + 24 versus 738 +/- 20 ml, and 8.5 +/- 0.3 versus 10.7 +/- 0.3 ml kg(-1), respectively; P < 0.001), oxygen saturation (95 +/- 0.4 versus 96 +/- 0.3%; P < 0.05), and partial pressure of oxygen (78 +/- 3 versus 87 +/- 3 mmHg; P < 0.05). Carbon dioxide levels were comparable (37 +/- 1 versus 37 +/- 1 mmHg). Our results indicate that smaller tidal volumes of about 8 ml x kg(-1) (approximately 600 ml), given with a new medium-size self-inflatable bag and room-air, maintained adequate carbon dioxide elimination and oxygenation during bag-valve-mask ventilation. Accordingly, the new medium-size self-inflatable bag may combine both adequate ventilatory support and reduced risk of gastric inflation during bag-valve-mask ventilation.


Assuntos
Oxigênio/administração & dosagem , Volume de Ventilação Pulmonar , Ventiladores Mecânicos , Adulto , Humanos , Cuidados para Prolongar a Vida/instrumentação , Cuidados para Prolongar a Vida/estatística & dados numéricos , Testes de Função Respiratória/estatística & dados numéricos , Estatísticas não Paramétricas , Ventiladores Mecânicos/estatística & dados numéricos
9.
Resuscitation ; 44(1): 37-41, 2000 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-10699698

RESUMO

The European Resuscitation Council has recommended decreasing tidal volume during basic life support ventilation from 800 to 1200 ml, as recommended by the American Heart Association, to 500 ml in order to minimise stomach inflation. However, if oxygen is not available at the scene of an emergency, and small tidal volumes are given during basic life support ventilation with a paediatric self-inflatable bag and room-air (21% oxygen), insufficient oxygenation and/or inadequate ventilation may result. When apnoea occurred after induction of anaesthesia, 40 patients were randomly allocated to room-air ventilation with either an adult (maximum volume, 1500 ml) or paediatric (maximum volume, 700 ml) self-inflatable bag for 5 min before intubation. When using an adult (n=20) versus paediatric (n=20) self-inflatable bag, mean +/-SEM tidal volumes and tidal volumes per kilogram were significantly (P<0.0001) larger (719+/-22 vs. 455+/-23 ml and 10.5+/-0.4 vs. 6.2+/-0.4 ml kg(-1), respectively). Compared with an adult self-inflatable bag, bag-valve-mask ventilation with room-air using a paediatric self-inflatable bag resulted in significantly (P<0.01) lower paO(2) values (73+/-4 vs. 87+/-4 mmHg), but comparable carbon dioxide elimination (40+/-2 vs. 37+/-1 mmHg; NS). In conclusion, our results indicate that smaller tidal volumes of approximately 6 ml kg(-1) ( approximately 500 ml) given with a paediatric self-inflatable bag and room-air maintain adequate carbon dioxide elimination, but do not result in sufficient oxygenation during bag-valve-mask ventilation. Thus, if small (6 ml kg(-1)) tidal volumes are being used during bag-valve-mask ventilation, additional oxygen is necessary. Accordingly, when additional oxygen during bag-valve-mask ventilation is not available, only large tidal volumes of approximately 11 ml kg(-1) were able to maintain both sufficient oxygenation and carbon dioxide elimination.


Assuntos
Máscaras Laríngeas , Sistemas de Manutenção da Vida/instrumentação , Consumo de Oxigênio/fisiologia , Respiração Artificial/instrumentação , Volume de Ventilação Pulmonar/fisiologia , Adulto , Animais , Criança , Pré-Escolar , Desenho de Equipamento , Feminino , Humanos , Masculino , Troca Gasosa Pulmonar/fisiologia , Respiração Artificial/métodos , Sensibilidade e Especificidade
10.
Resuscitation ; 49(2): 151-7, 2001 May.
Artigo em Inglês | MEDLINE | ID: mdl-11382520

RESUMO

This randomized controlled trial was designed to evaluate the effects of simulated emergency medical service (EMS) transport related stress on hemodynamic variables, and catecholamine plasma levels. A total of 32 healthy male volunteers were randomized to being carried by paramedics from a third-floor apartment through a staircase with subsequent high-speed EMS transport with lights and sirens (stress; n = 16); or sitting on a chair for 5 min, and lying on a stretcher for 15 min (control; n = 16). Blood samples and hemodynamic variables were taken in the apartment before transfer, at the ground floor, and at the end of EMS transport in the stress group, and at corresponding time points in the control group. The stress versus control group had both significantly (P < 0.05) higher mean +/- SEM epinephrine (71 +/- 7 versus 37 +/- 3 pg/ml), and norepinephrine (397 +/- 29 versus 299 +/- 28 pg/ml) plasma levels after transport through the staircase. After EMS transport, the stress versus control group had significantly higher epinephrine (48 +/-6 versus 32 +/- 2 pg/ml), but not norepinephrine (214 +/- 20 versus 264 +/- 31 pg/ml) plasma levels. Heart rate increased significantly from 72 +/- 2 to 84 +/- 3 bpm after staircase transport, but not during and after EMS transport. In conclusion, volunteers being carried by paramedics through a staircase had a significant discharge of both epinephrine and norepinephrine resulting in increased heart rate, but only elevated epinephrine plasma levels during EMS transport. Transport through a staircase may reflect more stress than emergency EMS transport.


Assuntos
Ambulâncias , Serviços Médicos de Emergência , Estresse Fisiológico/etiologia , Adulto , Epinefrina/sangue , Feminino , Frequência Cardíaca , Humanos , Masculino , Norepinefrina/sangue , Valores de Referência , Estresse Fisiológico/sangue , Estresse Fisiológico/fisiopatologia
11.
Resuscitation ; 51(2): 185-91, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11718975

RESUMO

Insufficient oxygenation, ventilation and gastric inflation with subsequent regurgitation of stomach contents is a major hazard of bag-valve-face mask ventilation during the basic life support phase of cardiopulmonary resuscitation (CPR). The European Resuscitation Council has recommended smaller tidal volumes of approximately 500 ml as an effort to reduce gastric inflation; furthermore, the intubating laryngeal mask airway and the laryngeal tube have been recently developed in order to provide rapid ventilation and to secure the airway. The purpose of our study was to examine whether usage of a newly developed medium-size self-inflating bag (maximum volume, 1100 ml) in association with the intubating laryngeal mask airway, and laryngeal tube may provide adequate lung ventilation, while reducing the risk of gastric inflation in a bench model simulating the initial phase of CPR. Twenty house officers volunteered for our study. When using the laryngeal tube, and the intubating laryngeal mask airway, respectively, the medium-size (maximum volume, 1100 ml) versus adult (maximum volume, 1500 ml) self-inflating bag resulted in significantly (P<0.05) lower mean+/-S.E.M. lung tidal volumes (605+/-22 vs. 832+/-4 ml, and 666+/-27 vs. 887+/-37 ml, respectively), but comparable peak airway pressures. No gastric inflation occurred when using both devices with either ventilation bag. In conclusion, both the intubating laryngeal mask airway and laryngeal tube in combination with both an 1100 and 1500 ml maximum volume self inflating bag proved to be valid alternatives for emergency airway management in a bench model of a simulated unintubated cardiac arrest victim.


Assuntos
Reanimação Cardiopulmonar/instrumentação , Dilatação Gástrica/prevenção & controle , Intubação Intratraqueal/efeitos adversos , Intubação Intratraqueal/instrumentação , Máscaras Laríngeas , Pneumonia Aspirativa/prevenção & controle , Adulto , Dilatação Gástrica/etiologia , Humanos , Manequins , Pneumonia Aspirativa/etiologia , Fatores de Risco , Volume de Ventilação Pulmonar
12.
Resuscitation ; 43(1): 25-9, 1999 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-10636314

RESUMO

OBJECTIVE: When ventilating an unintubated patient in cardiac or respiratory arrest, smaller tidal volumes of 500 ml instead of 800-1200 ml may be beneficial to decrease peak airway pressure, and to minimise stomach inflation. The purpose was to determine the effects of small (approximately 500 ml) versus large (approximately 1000 ml) tidal volumes given with paediatric versus adult self-inflatable bags and approximately 50% oxygen on respiratory parameters in patients during simulated basic life support ventilation. METHODS: While undergoing induction of anaesthesia, patients were randomised to three minutes of ventilation with either an adult (n = 40) or paediatric (n = 40) self-inflatable bag. RESULTS: When compared with an adult self-inflatable bag, the paediatric bag resulted in significantly lower mean (+/- standard deviation) exhaled tidal volume (365 +/- 55 versus 779 +/- 122 ml; P < 0.0001), peak airway pressure (20 +/- 2 versus 25 +/- 5 cm H2O; P < 0.0001), but comparable oxygen saturation (97 +/- 1% versus 98 +/- 1%; NS (nonsignificant)). Stomach inflation occurred in five of 40 patients ventilated with an adult self-inflatable bag, but in no patients who were ventilated with a paediatric self-inflatable bag (P = 0.054). CONCLUSION: Administering smaller tidal volumes with a paediatric instead of an adult self-inflatable bag in unintubated adult patients with respiratory arrest maintains good oxygenation and carbon dioxide elimination while decreasing peak airway pressure, which makes stomach inflation less likely.


Assuntos
Respiração Artificial , Insuficiência Respiratória/terapia , Adulto , Reanimação Cardiopulmonar/instrumentação , Reanimação Cardiopulmonar/métodos , Feminino , Humanos , Intubação Intratraqueal , Masculino , Volume de Ventilação Pulmonar , Ventiladores Mecânicos
13.
Resuscitation ; 49(2): 123-34, 2001 May.
Artigo em Inglês | MEDLINE | ID: mdl-11382517

RESUMO

The fear of acquiring infectious diseases has resulted in reluctance among healthcare professionals and the lay public to perform mouth-to-mouth ventilation. However, the benefit of basic life support for a patient in cardiopulmonary or respiratory arrest greatly outweighs the risk for secondary infection in the rescuer or the patient. The distribution of ventilation volume between lungs and stomach in the unprotected airway depends on patient variables such as lower oesophageal sphincter pressure, airway resistance and respiratory system compliance, and the technique applied while performing basic or advanced airway support, such as head position, inflation flow rate and time, which determine upper airway pressure. The combination of these variables determines gas distribution between the lungs and the oesophagus and subsequently, the stomach. During bag-valve-mask ventilation of patients in respiratory or cardiac arrest with oxygen supplementation (> or = 40% oxygen), a tidal volume of 6-7 ml kg(-1) ( approximately 500 ml) given over 1-2 s until the chest rises is recommended. For bag-valve-mask ventilation with room-air, a tidal volume of 10 ml kg(-1) (700-1000 ml) in an adult given over 2 s until the chest rises clearly is recommended. During mouth-to-mouth ventilation, a breath over 2 s sufficient to make the chest rise clearly (a tidal volume of approximately 10 ml kg(-1) approximately 700-1000 ml in an adult) is recommended.


Assuntos
Sistema Respiratório/fisiopatologia , Ressuscitação , História Antiga , História Moderna 1601- , Humanos , Infecções/etiologia , Respiração Artificial/efeitos adversos , Respiração Artificial/história , Respiração Artificial/métodos , Mecânica Respiratória , Dispositivos de Proteção Respiratória , Fatores de Risco
14.
J Emerg Med ; 20(1): 7-12, 2001 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11165830

RESUMO

The purpose of this study was to assess the levels of lung and gastric tidal volumes paramedics achieve when performing ventilation with bag-valve-mask, laryngeal mask, and Combitube. Twenty paramedics performed ventilation with a bag-valve mask, laryngeal mask, and Combitube in a bench model simulating an unintubated cardiorespiratory arrest patient. Lung and gastric tidal volumes and lung and gastric peak airway pressures were subsequently measured. The results showed that mean +/- SEM lung tidal volumes were significantly higher with the laryngeal mask and Combitube compared to the bag-valve-mask (701 +/- 264 vs. 742 +/- 311 vs. 353 +/- 110 mL, respectively). No gastric inflation occurred with the Combitube; gastric inflation was significantly lower with the laryngeal mask compared to the bag-valve-mask (25 +/- 15 vs. 230 +/- 25 mL, respectively). Both the laryngeal mask and Combitube proved to be valid alternatives for bag-valve-mask ventilation in our bench model simulating an unintubated patient with cardiorespiratory arrest.


Assuntos
Reanimação Cardiopulmonar/métodos , Parada Cardíaca/terapia , Máscaras Laríngeas , Pulmão/fisiologia , Estômago/fisiologia , Adulto , Resistência das Vias Respiratórias , Humanos , Modelos Biológicos , Estatísticas não Paramétricas , Volume de Ventilação Pulmonar
15.
Wien Klin Wochenschr ; 113(5-6): 186-93, 2001 Mar 15.
Artigo em Alemão | MEDLINE | ID: mdl-11293948

RESUMO

OBJECTIVES: Gastric inflation and regurgitation of stomach contents are major hazards of bag-valve-mask ventilation in an emergency. The purpose of our study was to determine lung ventilation and gastric inflation when using the bag-valve-face mask, laryngeal mask, and combitube with different sizes of self-inflating bags (max. volume: 700, 1100, 1500 ml). METHODS: Twenty-six training emergency doctors without prior extensive training in emergency airway management volunteered for our study and ventilated a bench model simulating an unintubated respiratory arrest patient with bag-valve-face mask, laryngeal mask, and combitube using paediatric, medium size, and adult self-inflating bags. Lung and gastric tidal volume, as well as lung and gastric peak airway pressure were measured with respiratory monitors and a pneumotachometer. RESULTS: When using either the combitube or the laryngeal mask, the paediatric vs. medium-size and adult self-inflating bag resulted in significantly (P < .001) lower mean +/- SEM lung tidal volumes (328 +/- 34 vs. 626 +/- 65 vs. 654 +/- 69 ml; and 368 +/- 30 vs. 532 +/- 48 vs. 692 +/- 67 ml, respectively). No gastric inflation occurred with the combitube, while gastric inflation was comparably low when using the laryngeal mask with either ventilation bag (3 +/- 2 vs. 7 +/- 4 vs. 6 +/- 3 ml; P = NS). The paediatric vs. medium-size and adult self-inflating bag in combination with the bag-valve-face mask resulted in comparable lung tidal volumes (250 +/- 23 vs. 313 +/- 24 vs. 282 +/- 38 ml; P = NS); but significantly (P < .01) lower gastric tidal volumes (147 +/- 23 vs. 206 +/- 24 vs. 267 +/- 23 ml). CONCLUSIONS: Both the laryngeal mask and the combitube proved to be valid alternatives for the bag-valve-face mask in our experimental model. The medium size self-inflating bag seems to be adequate when using either the laryngeal mask or the combitube.


Assuntos
Máscaras Laríngeas , Respiração Artificial/instrumentação , Respiração Artificial/métodos , Volume de Ventilação Pulmonar , Adulto , Reanimação Cardiopulmonar/instrumentação , Reanimação Cardiopulmonar/métodos , Feminino , Humanos , Máscaras Laríngeas/efeitos adversos , Masculino , Respiração Artificial/efeitos adversos
16.
Minerva Anestesiol ; 79(2): 121-9, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23032922

RESUMO

BACKGROUND: Recently, indirect videolaryngoscopes have become increasingly important devices in difficult airway management. The aim of the present study was to investigate laryngoscopic view and intubation success using the new C-MAC® D-Blade in comparison to the established GlideScope® videolaryngoscope and conventional direct laryngoscopy in a randomized controlled trial. METHODS: Ninety-six adult patients with expected difficult airways undergoing elective ear, nose and throat surgery (ENT) requiring general anesthesia were investigated. Repeated laryngoscopy was performed using a conventional direct Macintosh laryngoscope (DL), C-MAC D-Blade (DB) and GlideScope (GS) in a randomized sequence before patients were intubated with the last device used. RESULTS: Both videolaryngoscopes showed significantly better C/L (Cormack-Lehane) classes than DL. Insufficient laryngoscopic view, defined as C/L ≥ III, was experienced in 18 patients (19.2%) with DL, in two patients with GS (2.1%) and in none with DB (0%). Time to best achievable laryngoscopic view did not differ between devices. Intubation time was significantly longer with both videolaryngoscopes (Median [Range] DB: 18 [8-33] s, and GS: 19 [9-34] s) than with DL (11 [5-26] s). However, intubation success was 100% for both DB and GS, whereas four patients could not be intubated using conventional direct laryngoscopy. CONCLUSION: Compared to direct Macintosh laryngoscopy, both C-MAC® D-Blade and GlideScope® comparably resulted in an improved view of the glottic opening with successful tracheal intubation in all patients.


Assuntos
Manuseio das Vias Aéreas/instrumentação , Manuseio das Vias Aéreas/métodos , Intubação Intratraqueal/instrumentação , Intubação Intratraqueal/métodos , Laringoscópios , Laringoscopia/instrumentação , Adulto , Idoso , Feminino , Glote/anatomia & histologia , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Otorrinolaringológicos/instrumentação , Gravação em Vídeo
17.
Anaesthesist ; 56(2): 145-8, 150, 2007 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-17265038

RESUMO

While fluid management is established in controlled hemorrhagic shock, its use in uncontrolled hemorrhagic shock is being controversially discussed, because it may worsen bleeding. In the irreversible phase of hemorrhagic shock that was unresponsive to volume replacement, airway management and catecholamines, vasopressin was beneficial due to an increase in arterial blood pressure, shift of blood away from a subdiaphragmatic bleeding site towards the heart and brain and decrease of fluid resuscitation requirements. The purpose of this multicenter, randomized, controlled, international trial is to assess the effects of vasopressin (10 IU IV) vs. saline placebo IV (up to 3 injections at least 5 min apart) in patients with prehospital traumatic hemorrhagic shock that persists despite standard shock treatment. The study will be carried out by helicopter emergency medical service teams in Austria, Germany, Czech Republic, Portugal, the Netherlands and Switzerland. Inclusion criteria are adult trauma patients with presumed traumatic hemorrhagic shock (systolic arterial blood pressure <90 mmHg) that does not respond to the first 10 min of standard shock treatment (endotracheal intubation, fluid resuscitation and use of vasopressors) after arrival of the first emergency physician at the scene. The time window for randomization will close after 30 min of shock treatment. Exclusion criteria are terminal illness, no intravenous access, age <18 years, injury >60 min before randomization, cardiac arrest before randomization, presence of a do-not-resuscitate order, untreated tension pneumothorax, untreated cardiac tamponade, or known pregnancy. Primary study end-point is the hospital admission rate, secondary end-points are hemodynamic variables, fluid resuscitation requirements and hospital discharge rate.


Assuntos
Choque Hemorrágico/terapia , Vasoconstritores/uso terapêutico , Vasopressinas/uso terapêutico , Ferimentos e Lesões/complicações , Resgate Aéreo , Pressão Sanguínea/efeitos dos fármacos , Pressão Sanguínea/fisiologia , Método Duplo-Cego , Serviços Médicos de Emergência , Determinação de Ponto Final , Humanos , Ordens quanto à Conduta (Ética Médica) , Choque Hemorrágico/etiologia
18.
Eur J Anaesthesiol ; 23(6): 501-9, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16507191

RESUMO

BACKGROUND AND OBJECTIVE: The present study was designed to compare cerebral oxygenation measured with near infrared spectroscopy and local brain tissue oxygen partial pressure, respectively, in pigs during cardiopulmonary resuscitation. Since tissue overlying the brain may have an impact on near infrared spectroscopy readings, we tested whether optode placement on intact skin or on the skull yielded comparable results. METHODS: Twelve healthy pigs were anaesthetized and subjected to continuous haemodynamic, near infrared spectroscopy and brain tissue oxygen partial pressure monitoring. After 4 min of untreated ventricular fibrillation, cardiopulmonary resuscitation was started and arginine vasopressin was administered repeatedly three times. Near infrared spectroscopy values recorded were both the tissue oxygenation index and the tissue haemoglobin index as well as relative changes of chromophores (haemoglobin and cytochrome oxidase). Four animals served as control and were measured with both near infrared spectroscopy optodes mounted on the intact skin of the forehead, while in the remaining eight animals, one near infrared spectroscopy optode was implanted directly on the skull. RESULTS: Near infrared spectroscopy readings at the skin or at the skull differed consistently throughout the study period. After arginine vasopressin administration, near infrared spectroscopy values at the different locations showed a transient dissociation. In contrast to near infrared spectroscopy measured on intact skin, near infrared spectroscopy readings obtained from skull showed a significant correlation to brain tissue oxygen partial pressure values (r = 0.67, P < 0.001). CONCLUSION: Near infrared spectroscopy readings obtained from skin and skull differed largely after vasopressor administration. Near infrared spectroscopy optode placement therefore may have an important influence on the tissue region investigated.


Assuntos
Encéfalo/metabolismo , Reanimação Cardiopulmonar/métodos , Circulação Cerebrovascular/fisiologia , Oxigênio/metabolismo , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Animais , Arginina Vasopressina/administração & dosagem , Pressão Sanguínea/fisiologia , Encéfalo/irrigação sanguínea , Complexo IV da Cadeia de Transporte de Elétrons/metabolismo , Hemoglobinas/metabolismo , Modelos Animais , Monitorização Fisiológica/métodos , Pressão Parcial , Pele/metabolismo , Crânio/metabolismo , Suínos , Fatores de Tempo , Vasoconstritores/administração & dosagem
19.
Anaesthesist ; 55(9): 958-66, 968-72, 974-9, 2006 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-16915404

RESUMO

The new CPR guidelines are based on a scientific consensus which was reached by 281 international experts. Chest compressions (100/min, 4-5 cm deep) should be performed in a ratio of 30:2 with ventilation (tidal volume 500 ml, Ti 1 s, FIO2 if possible 1.0). After a single defibrillation attempt (initially biphasic 150-200 J, monophasic 360 J, subsequently with the respective highest energy), chest compressions are initiated again immediately for 2 min. Endotracheal intubation is the gold standard; other airway devices may be employed as well depending on individual skills. Drug administration routes for adults and children: first choice IV, second choice intraosseous, third choice endobronchial [epinephrine dose 2-3x (adults) or 10x (pediatric patients) higher than IV]. Vasopressors: 1 mg epinephrine every 3-5 min IV. After the third unsuccessful defibrillation attempt amiodarone IV (300 mg); repetition (150 mg) possible. Sodium bicarbonate (1 ml/kg 8.4%) only in excessive hyperkalemia, metabolic acidosis, or intoxication with tricyclic antidepressants. Consider atropine (3 mg) and aminophylline (5 mg/kg). Thrombolysis during spontaneous circulation only in myocardial infarction or massive pulmonary embolism; during CPR only during massive pulmonary embolism. Cardiopulmonary bypass only after cardiac surgery, hypothermia or intoxication. Pediatrics: best improvement in outcome by preventing cardiocirculatory collapse. Alternate chest thumps and chest compression (infants), or abdominal compressions (>1-year-old) in foreign body airway obstruction. Initially five breaths, followed by chest compressions (100/min; approximately 1/3 of chest diameter): ventilation ratio 15:2. Treatment of potentially reversible causes (4 "Hs", "HITS": hypoxia, hypovolemia, hypo- and hyperkaliemia, hypothermia, cardiac tamponade, intoxication, thrombo-embolism, tension pneumothorax). Epinephrine 10 microg/kg IV or intraosseously, or 100 microg (endobronchially) every 3-5 min. Defibrillation (4 J/kg; monophasic oder biphasic) followed by 2 min CPR, then ECG and pulse check. Newborns: inflate the lungs with bag-valve mask ventilation. If heart rate<60/min chest compressions:ventilation ratio 3:1 (120 chest compressions/min). Postresuscitation phase: initiate mild hypothermia [32-34 degrees C for 12-24 h; slow rewarming (<0.5 degrees C/h)]. Prediction of CPR outcome is not possible at the scene; determining neurological outcome within 72 h after cardiac arrest with evoked potentials, biochemical tests and physical examination. Even during low suspicion for an acute coronary syndrome, record a prehospital 12-lead ECG. In parallel to pain therapy, aspirin (160-325 mg PO or IV) and in addition clopidogrel (300 mg PO). As antithrombin, heparin (60 IU/kg, max. 4000 IU) or enoxaparine. In ST-segment elevation myocardial infarction, define reperfusion strategy depending on duration of symptoms until PCI (prevent delay>90 min until PCI). Stroke is an emergency and needs to be treated in a stroke unit. A CT scan is the most important evaluation, MRT may replace a CT scan. After hemorrhage exclusion, thrombolysis within 3 h of symptom onset (0.9 mg/kg rt-PA IV; max 90 mg within 60 min, 10% of the entire dosage as initial bolus, no aspirin, no heparin within the first 24 h). In severe hemorrhagic shock, definite control of bleeding is the most important goal. For successful CPR of trauma patients, a minimal intravascular volume status and management of hypoxia are essential. Aggressive fluid resuscitation, hyperventilation, and excessive ventilation pressure may impair outcome in severe hemorrhagic shock. Despite bad prognosis, CPR in trauma patients may be successful in select cases. Any CPR training is better than nothing; simplification of contents and processes remains important.


Assuntos
Reanimação Cardiopulmonar/normas , Adulto , Antiarrítmicos/uso terapêutico , Broncodilatadores/uso terapêutico , Reanimação Cardiopulmonar/instrumentação , Criança , Doença das Coronárias/terapia , Cardioversão Elétrica , Serviços Médicos de Emergência , Europa (Continente) , Humanos , Hipotermia Induzida , Recém-Nascido , Prognóstico , Respiração Artificial , Choque/prevenção & controle , Terapia Trombolítica , Vasoconstritores/uso terapêutico , Equilíbrio Hidroeletrolítico/efeitos dos fármacos , Ferimentos e Lesões/terapia
20.
Eur J Anaesthesiol ; 22(5): 341-6, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15918381

RESUMO

BACKGROUND AND OBJECTIVE: This study was performed to compare three supraglottic airway devices: the ProSeal laryngeal mask airway (PLMA), the laryngeal tube S (LTS) and the oesophageal-tracheal combitube (OTC) during routine surgical procedures. METHODS: Ninety American Society of Anesthesiologists (ASA) I-III patients scheduled for routine minor obstetric surgery were randomly allocated to the PLMA (n = 30), the LTS (n = 30) or the OTC (n = 30) group, respectively. The overall success rate, insertion time, cuff pressures and resulting airway leak pressures were determined as well as a subjective assessment of handling and the incidence of sore throat, dysphagia and hoarseness were performed. RESULTS: Insertion time until the first adequate ventilation was significantly (P < 0.0001) shorter in the PLMA (median 29 s; 25-75th percentile 25-48 s; range 10-161 s; success rate 100%) and in the LTS group (38 s; 30-44 s; 13-180 s; 100%) compared to the OTC group (75 s; 48-98 s; 35-180 s; 90%). In vivo cuff pressures and airway leak pressures increased with the inflating cuff volume in all devices and were highest in the OTC group. Postoperatively, patients in the PLMA and the LTS group complained significantly less about sore throat (P < 0.001 and 0.05) and dysphagia (P < 0.001 and 0.02) compared to the OTC group, while there was no difference regarding the incidence of hoarseness. Subjective assessment of handling was comparable with the PLMA and the LTS, but inferior with the OTC. CONCLUSIONS: In conclusion, both PLMA and LTS proved to be suitable for routine surgical procedures and proved to be superior to the OTC which cannot be recommended for routine use.


Assuntos
Intubação Intratraqueal/instrumentação , Intubação Intratraqueal/métodos , Máscaras Laríngeas , Procedimentos Cirúrgicos Obstétricos , Pressão Sanguínea/fisiologia , Transtornos de Deglutição/etiologia , Eletroencefalografia/métodos , Feminino , Frequência Cardíaca/fisiologia , Rouquidão/etiologia , Humanos , Intubação Intratraqueal/efeitos adversos , Máscaras Laríngeas/efeitos adversos , Pessoa de Meia-Idade , Monitorização Intraoperatória/métodos , Faringite/etiologia , Pressão , Fatores de Tempo , Resultado do Tratamento
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