RESUMO
We studied hepatitis B virus surface antigen (HBsAg), surface antibody (HBsAb) and "core" antibody (HBcAb) prevalence in 166 among hospital personell and patients with and without liver disease. Results show there is a very high prevalence of hepatitis B virus markers in such populations and the presence of HBcAb in absence of the other markers varies from 6% in "high risk" subjects to 30.3% in cirrhotic patients. We conclude that HBcAb seems to be, at moment, the most sensitive serological marker either for epidemiological studies or diagnosis and, in some instances, for prognosis of hepatitis B virus liver diseases.
Assuntos
Anticorpos Antivirais/análise , Anticorpos Anti-Hepatite B/análise , Antígenos de Superfície da Hepatite B/análise , Hepatite Viral Humana/imunologia , Hepatopatias/imunologia , Recursos Humanos em Hospital , Adolescente , Adulto , Idoso , Criança , Feminino , Hepatite B/imunologia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
By excluding the CALD complicated by B.H.N. we have been left with a range of C.A.H. patterns hardly distinguishable from C.P.H. on one side and from Cirrhosis on the other. We have tried to subdivide this range into three subgroups according to the extension of necrosis, fibrosis, inflammation, regeneration. Furthermore, we compared the biochemical parameters of activity of these subgroups in which we subdivided C.A.H. without B.H.N. to each other and with those of C.P.H. and C.L.H. Results shaw no statistical significative difference in the compared groups. Thus, we conclude for a priority of the histological patterns on biochemical parameters in the management of this disease.
Assuntos
Hepatite/classificação , Alanina Transaminase/sangue , Aspartato Aminotransferases/sangue , Proteínas Sanguíneas/análise , Doença Crônica , Hepatite/complicações , Hepatite/patologia , Humanos , Imunoglobulinas/análise , Fígado/patologia , Necrose/complicações , gama-Globulinas/análiseRESUMO
Partial nodular transformation is a rare disorder of the liver, that is becoming a very interesting speculative problem, in relation to the nodular regenerative hyperplasia of the liver and cirrhosis. This disease is a cause of non cirrhotic protal hypertension. Clinical and pathological aspects are discussed a propos of a case.