RESUMO
The COMPASS Collaboration performed measurements of the Drell-Yan process in 2015 and 2018 using a 190 GeV/c π^{-} beam impinging on a transversely polarized ammonia target. Combining the data of both years, we present final results on the amplitudes of five azimuthal modulations, which correspond to transverse-spin-dependent azimuthal asymmetries (TSAs) in the dimuon production cross section. Three of them probe the nucleon leading-twist Sivers, transversity, and pretzelosity transverse-momentum dependent (TMD) parton distribution functions (PDFs). The other two are induced by subleading effects. These TSAs provide unique new inputs for the study of the nucleon TMD PDFs and their universality properties. In particular, the Sivers TSA observed in this measurement is consistent with the fundamental QCD prediction of a sign change of naive time-reversal-odd TMD PDFs when comparing the Drell-Yan process with deep inelastic scattering. Also, within the context of model predictions, the observed transversity TSA is consistent with the expectation of a sign change for the Boer-Mulders function.
RESUMO
The COMPASS Collaboration experiment recently discovered a new isovector resonancelike signal with axial-vector quantum numbers, the a_{1}(1420), decaying to f_{0}(980)π. With a mass too close to and a width smaller than the axial-vector ground state a_{1}(1260), it was immediately interpreted as a new light exotic meson, similar to the X, Y, Z states in the hidden-charm sector. We show that a resonancelike signal fully matching the experimental data is produced by the decay of the a_{1}(1260) resonance into K^{*}(âKπ)K[over ¯] and subsequent rescattering through a triangle singularity into the coupled f_{0}(980)π channel. The amplitude for this process is calculated using a new approach based on dispersion relations. The triangle-singularity model is fitted to the partial-wave data of the COMPASS experiment. Despite having fewer parameters, this fit shows a slightly better quality than the one using a resonance hypothesis and thus eliminates the need for an additional resonance in order to describe the data. We thereby demonstrate for the first time in the light-meson sector that a resonancelike structure in the experimental data can be described by rescattering through a triangle singularity, providing evidence for a genuine three-body effect.
RESUMO
The study was aimed to compare efficiency of optimized and combined treatment and rehabilitation in post-apoplexy patients, using standard therapy, cytoflavin and COBS-training. The study involved 51 patients in early (n = 25) and late (n = 26) recovery periods after CVA. Reference groups included patients in early (n = 15) and late (n = is) recovery periods, receiving basic therapy. Evaluations included thepatients' complaints change, activity index (Bartel scale), neurologic state (NIHSS scale), static and locomotory disorders intensity (M.E. Tinetti scale), ultrasound dopplerography, MALDI-TOF-TOF mass spectrometry of serum. Implementation of cytoflavin and COBS-training in CVA patients in early recovery period resulted in better life quality, decrease in neurologi deficit, less static and locomotory disorders, increased average blood velocity, RI, PI on ICA siphon and lower average blood velocity, RI, PI on MCA in comparison with reference groups and CVA patients in late recovery period. Findings are molecular groups of cellular apoptosis, autophagy, necroptosis, ER stress in serum -. explanation of additional links of cytoflavin and COBS-training action mechanism in post-apoplexy patients.
Assuntos
Mononucleotídeo de Flavina/uso terapêutico , Inosina Difosfato/uso terapêutico , Locomoção , Niacinamida/uso terapêutico , Qualidade de Vida , Reabilitação do Acidente Vascular Cerebral/métodos , Acidente Vascular Cerebral , Succinatos/uso terapêutico , Combinação de Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Exame Neurológico/métodos , Fármacos Neuroprotetores/uso terapêutico , Recuperação de Função Fisiológica/efeitos dos fármacos , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz/métodos , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/tratamento farmacológico , Acidente Vascular Cerebral/metabolismo , Acidente Vascular Cerebral/fisiopatologia , Reabilitação do Acidente Vascular Cerebral/psicologia , Resultado do Tratamento , Ultrassonografia Doppler Dupla/métodosRESUMO
A prospective, placebo-controlled ordinary-"blind"-randomized investigation of the cytoflavine effect on roentgenological manifestations of exudative-destructive processes in pulmonary tissues in cases of tuberculosis in children and teenagers has been performed in comparison to changes in the the functional state of neutrophilic granulocytes and Micobacterium tuberculosis incidence in sputum during a standard four-months course of antituberculosis therapy. It is estasblished that the administration of cytoflavine at the beginning of antituberculosis complex therapy (10 mL per 24 hours, for 5 days) results in rapid suppression of exudative-destructive disease manifestations and quick cavity repair in tuberculosis-affected areas, at an increase in the probability of outcome with "small post-tuberculosis changes". The rapid suppression of exudative-destructive processes in patients having received cytoflavine was caused by its optimizing influence on phagocytic blood capacity and did not depend on the development of abacillarity in patients.
Assuntos
Antituberculosos/administração & dosagem , Mononucleotídeo de Flavina/administração & dosagem , Inosina Difosfato/administração & dosagem , Niacinamida/administração & dosagem , Succinatos/administração & dosagem , Tuberculose Pulmonar/tratamento farmacológico , Tuberculose Pulmonar/metabolismo , Adolescente , Criança , Combinação de Medicamentos , Feminino , Humanos , Pulmão/metabolismo , Pulmão/microbiologia , Pulmão/patologia , Masculino , Mycobacterium tuberculosis , Neutrófilos/metabolismo , Neutrófilos/microbiologia , Estudos Prospectivos , Escarro/metabolismo , Escarro/microbiologia , Fatores de Tempo , Tuberculose Pulmonar/microbiologia , Tuberculose Pulmonar/patologiaRESUMO
We report a case of fatal sodium poisoning due to the unintentional use of 20% hypertonic saline serum during peritoneal lavage after intestinal resection. The patient presented with unconsciousness, metabolic acidosis, and plasma sodium concentration of 193 mE/l. After 3 hours, he developed paroxysmal supraventricular tachycardia, hyperthermia, generalized tonic-clonic convulsions, disseminated intravascular coagulation, and adult respiratory distress syndrome. The patient died 15 hours after the operation. Pathological examination revealed cerebral and lung oedema, pericentral hepatic necrosis, and fibrin thrombi in the lungs, stomach, and kidneys. We review, in addition, other reported cases of sodium poisoning.
Assuntos
Acidose/induzido quimicamente , Hipernatremia/induzido quimicamente , Lavagem Peritoneal/efeitos adversos , Solução Salina Hipertônica/efeitos adversos , Acidose/terapia , Evolução Fatal , Humanos , Hipernatremia/terapia , Masculino , Pessoa de Meia-Idade , Concentração Osmolar , Solução Salina Hipertônica/administração & dosagemAssuntos
Primeiros Socorros/normas , Medicina Naval/normas , Telemedicina/normas , Equipamentos e Provisões , Primeiros Socorros/instrumentação , Primeiros Socorros/métodos , Guias como Assunto , Humanos , Medicina Naval/métodos , Preparações Farmacêuticas/administração & dosagem , Telemedicina/métodos , Organização Mundial da SaúdeRESUMO
Reaction to infusion of 7.5% sodium chloride solution was studied in 81 patients with endogenous intoxication during development of critical arterial hypotension which could not be prevented or arrested by routine high-dose therapy. The reaction was considered adequate on condition that arterial pressure increased no higher than the safe level, subsequent maintenance of hemodynamics was effective, toxin binding with plasma albumin was increased, diuresis increased, and hypernatriemia was transitory in the presence of general improvement of patient's status. Such a reaction was observed in 83% patients. The efficiency of this method is determined by indications for low-dose therapy and probability of adequate reaction to infusion.