The influence of age on length of stay, functional independence and discharge destination of rehabilitation inpatients in Italy.

Advanced age in itself does not predict a poor functional outcome or a longer length of stay in rehabilitation units. Seven hundred and sixty-four adult cases were analysed, from 14 post-acute rehabilitation facilities throughout Italy. Data came from the national database run by the agency distributing the Italian version of an internationally validated scale of disability, the FIM [symbol: see text] sm (Functional Independence Measure). The FIM is an 18-item scale rating independence in the domains of selfcare, sphincter control, mobility, locomotion, communication and social cognition. The total FIM score may range from 18 to 126 (higher score = greater independence). Patients were classified with respect to the cut-off age of 75 years (76+ and 75-, mean age 82 and 57 years, n = 203 and 561, 27% and 73% of the cases, respectively). The median interval between onset of disability and admission to the facility (onset-to-admission delay, OAD) was 36 and 45 days in the 76+ and the 75- group, respectively (p < 0.001). Mean admission FIM score was 70 (+/- 28) in the 76+ and 71 (+/- 27) in the 75- group. Discharge FIM scores were 84 +/- 29 and 93 +/- 26, respectively (p < 0.001). Median length of stay (LOS) was 34 days in the 76+ and 41 days in the 75- group, respectively (p < 0.005). The 76+ and 75- groups were discharged home in 86% and 90% of the cases, respectively (p = 0.053). The results suggest that inpatient rehabilitation is substantially effective and efficient for older as well as for younger patients.

[Computerized analysis of the effects of age on posture control]. / Analisi con sistema computerizzato degli effetti dell'età sul controllo posturale.

The authors examined postural sway in 112 normal subjects by means of a computerized force platform system. The performances of 14 subjects (7 males and 7 females) for each of these age groups: 12-15, 16-19 and the six next decades until 79 years were considered. The posturographic test requires two trials, one with eyes open and another with eyes closed, with patients in Romberg's position. On the average eyes-closed measurements have always been greater than those with eyes open. Moreover this study shows that during the growth the characteristics of postural control are different between the two sexes and as regards adult performances. During ageing a progressive significant stability impairment, especially upon visual deprivation, was shown.

A short measure of balance in multiple sclerosis: validation through Rasch analysis.

Ambulatory patients with multiple sclerosis (MS) frequently present with poor balance. Neither static nor dynamic posturography explore balance during self-paced movements in real-life activities, when fall is most probable. Behavioural item-response scales can easily represent these activities. However, testing many items can easily cause fatigue in MS patients, thus distorting their scores. On the other hand, the lower the number of items, the lower the precision of the cumulative score and its reliability. A new short instrument was derived from existing ones (the Tinetti and the Berg balance scales). A preliminary 10-item version encompassed sit/stand manoeuvres, standing with eyes open and closed, standing with eyes closed and head extended, leaning forward while standing, picking up an object from floor, resisting nudges on the sternum, turning around, tandem stance. The instrument was administered 1-3 times to 55 MS patients (103 observations overall), all of them able to walk autonomously for at least 20 metres. The Rasch Analysis was adopted to explore the psychometric validity of the scale. Two items (Stand-to-sit and Standing with eyes open) were deleted, as they were too easy and thus uninformative. The remaining 8 items made up a scale (called EQUI-SCALE) complying with the requirements of unidimensionality and reliability. The item scores remained stable in a sub-sample of 24 patients tested before and after ten 1-hour exercise sessions, thus supporting the homogeneity of the items.

[Parkinson syndrome induced by veralipride]. / Sindrome parkinsoniana indotta da veralipride.

Veralipride, an antidopaminergic drug commonly prescribed to counteract postmenopausal symptoms, may cause reversible parkinsonism. A 49-year-old healthy woman reported a 5 month history of progressive slowing of voluntary movements, postural changes, e.g. sit-to-stand manouevres, and gait. Clinical examination revealed moderate hypokinesia, hypomimia and plastic rigidity of the four limbs. Locomotor oscillations of the upper limbs were decreased. She had been taking 100 mg of veralipride daily to counteract postmenopausal symptoms (vasomotor flushes and irritability) for 17 months uninterruptedly. The drug was withdrawn. The patient's clinical picture fully normalized within 20 days. One year later she reported to be still asymptomatic. This seems to be a case of parkinsonism induced by veralipride, a drug known to cause other extrapiramidal signs such as bucco-facial or limb dyskinesia. To our knowledge, only one other such case has been published (a 77-year-old French woman who had been taking veralipride, prazepam and nicergolin). In both cases, the drug had been administered for longer and without intervals. In our patient the motor disturbances could not have been associated with either advanced age or interaction with concurrent medications. Therefore, this case is suspected for veralipride-associated parkinsonism. In conclusion, intoxication should be thought in case of parkinsonism arising in women taking this drug.

Rehabilitation: the Cinderella of neurological research? A bibliometric study.

Rehabilitation is under-represented in the neurological literature on disabling diseases. A Medline search was conducted to retrieve the articles published between January 1991 and June 1994 under the main headings of Stroke, Parkinson's disease, Multiple sclerosis, Brain injury, Ataxia and Dementia. These were then combined with the sub-heading Rehabilitation. The former search yielded 27724 articles, the latter 1272 (4.6%). In 1992, the Journal of Citation Reports (JCR) assigned to Journals publishing rehabilitation papers an average Impact Factor (IF) of 0.7-2.8 (median 1.8): that is, 31-90% (depending on the various main headings, median 68%) of the average IF given to Journals publishing non-rehabilitation papers. In the present study, the weight of the literature was defined as the product of the number of articles multiplied by the IF of the corresponding Journal (IF = 0 for non-JCR Journals). Across the various neurologic conditions, the weight of the Rehab literature was 0.1-7% (median 2%) of the weight of the non-Rehab literature. The results suggest that neurology is still reluctant to face the disability challenge.

Trunk control test as an early predictor of stroke rehabilitation outcome.

BACKGROUND AND PURPOSE: The aim of this study was to investigate the construct and predictive validity of the Trunk Control Test (TCT) in postacute stroke patients by comparing TCT scores at admission and discharge with the Functional Independence Measure (FIM) scores. METHODS: Forty-nine patients participated in the study. The TCT examines four movements: rolling from a supine position to the weak side (T1) and to the strong side (T2), sitting up from a lying-down position (T3), and sitting balance (T4). The FIM is an 18-item scale (13 motor [motFIM] and 5 cognitive [cognFIM]) used to determine the level of dependence of patients in daily life. RESULTS: Thirty-six patients (73%) increased their TCT overall score at discharge. The TCT item-total correlations were high, both at admission and discharge (P < .0001). The individual TCT items were intercorrelated. Furthermore, the homogeneity of the TCT was confirmed by a high Cronbach's index. High correlations were found between admission and discharge scores in the different tests (TCT, FIM, and motFIM; P < .0001) and between TCT at admission and FIM (P < .0001) and motFIM (P < .0001) at admission. TCT at admission alone explained 71% of the variance in motFIM at discharge. CONCLUSIONS: The TCT showed a good sensitivity to change in assessing recovery of stroke patients. The high item-total correlation and Cronbach's alpha value of the TCT suggest that there is one homogeneous construct underlying the item list. The TCT construct validity was confirmed by the correlation between this test and the FIM scores. TCT at admission predicted motFIM at discharge even better than motFIM at admission alone. Possibly, the TCT captures basic motor skills that foreshadow the recovery of more complex behavioral skills described by the FIM.