RESUMO
Characteristics of cognitive deficits in benign childhood epilepsy with centrotemporal spikes (BECTS) remain unclear. The authors screened 200 BECTS children presenting for a clinical trial, finding relative weaknesses in fine motor control, visual learning, and attention in the presence of overall normal intellect, with simple partial seizures associated with more difficulty. Parental concerns for psychosomatic and learning problems were noted. Monitoring select cognitive and behavioral features in BECTS appears appropriate.
Assuntos
Transtornos Cognitivos/etiologia , Epilepsia Rolândica/complicações , Deficiências da Aprendizagem/etiologia , Transtornos Mentais/etiologia , Anticonvulsivantes/uso terapêutico , Criança , Epilepsia Rolândica/tratamento farmacológico , Epilepsia Rolândica/psicologia , Feminino , Humanos , Inteligência , Masculino , Convulsões/classificaçãoRESUMO
A simple semi-quantitative assay method for proteolytic enzyme solutions used in blood group serology is described. The method is an adaptation of a technique formerly used for assay of faecal trypsin and is based on the digestion of the gelatin coating of unexposed X-ray film. A Spearman rank correlation coefficient of 0.8 was obtained when the X-ray film technique was compared with a spectrophotometric method using azoalbumin as substrate. The method is not suitable as a reference technique or as a substitute for serological control, but is useful for monitoring or comparing enzyme preparations in some circumstances or situations.