Pesquisa | BVS Educação Profissional em Saúde

1.

EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials.

Stokke, Caroline; Gnesin, Silvano; Tran-Gia, Johannes; Cicone, Francesco; Holm, Søren; Cremonesi, Marta; Blakkisrud, Johan; Wendler, Thomas; Gillings, Nic; Herrmann, Ken; Mottaghy, Felix M; Gear, Jonathan.

Eur J Nucl Med Mol Imaging ; 51(5): 1268-1286, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38366197

2.

Stress Hormone Dynamics Are Coupled to Brain Serotonin 4 Receptor Availability in Unmedicated Patients With Major Depressive Disorder: A NeuroPharm Study.

Vulpius, Gunild M; Köhler-Forsberg, Kristin; Ozenne, Brice; Larsen, Søren V; Nasser, Arafat; Svarer, Claus; Gillings, Nic; Keller, Sune H; Jørgensen, Martin B; Knudsen, Gitte M; Frokjaer, Vibe G.

Int J Neuropsychopharmacol ; 26(9): 639-648, 2023 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-37542733

3.

EANM guideline on quality risk management for radiopharmaceuticals.

Gillings, Nic; Hjelstuen, Olaug; Behe, Martin; Decristoforo, Clemens; Elsinga, Philip H; Ferrari, Valentina; Kiss, Oliver C; Kolenc, Petra; Koziorowski, Jacek; Laverman, Peter; Mindt, Thomas L; Ocak, Meltem; Patt, Marianne; Todde, Sergio; Walte, Almut.

Eur J Nucl Med Mol Imaging ; 49(10): 3353-3364, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35385986

4.

Serotonin 2A receptor agonist binding in the human brain with [(11)C]Cimbi-36: Test-retest reproducibility and head-to-head comparison with the antagonist [(18)F]altanserin.

Ettrup, Anders; Svarer, Claus; McMahon, Brenda; da Cunha-Bang, Sofi; Lehel, Szabolcs; Møller, Kirsten; Dyssegaard, Agnete; Ganz, Melanie; Beliveau, Vincent; Jørgensen, Louise Møller; Gillings, Nic; Knudsen, Gitte Moos.

Neuroimage ; 130: 167-174, 2016 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-26876490

5.

The Center for Integrated Molecular Brain Imaging (Cimbi) database.

Knudsen, Gitte M; Jensen, Peter S; Erritzoe, David; Baaré, William F C; Ettrup, Anders; Fisher, Patrick M; Gillings, Nic; Hansen, Hanne D; Hansen, Lars Kai; Hasselbalch, Steen G; Henningsson, Susanne; Herth, Matthias M; Holst, Klaus K; Iversen, Pernille; Kessing, Lars V; Macoveanu, Julian; Madsen, Kathrine Skak; Mortensen, Erik L; Nielsen, Finn Årup; Paulson, Olaf B; Siebner, Hartwig R; Stenbæk, Dea S; Svarer, Claus; Jernigan, Terry L; Strother, Stephen C; Frokjaer, Vibe G.

Neuroimage ; 124(Pt B): 1213-1219, 2016 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25891375

6.

Metabolic Fate of Hallucinogenic NBOMes.

Leth-Petersen, Sebastian; Gabel-Jensen, Charlotte; Gillings, Nic; Lehel, Szabolzs; Hansen, Hanne D; Knudsen, Gitte M; Kristensen, Jesper L.

Chem Res Toxicol ; 29(1): 96-100, 2016 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-26669514

7.

Convergent ¹⁸F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT_2A receptor PET ligands.

Petersen, Ida Nymann; Villadsen, Jonas; Hansen, Hanne Demant; Jensen, Anders A; Lehel, Szabolcs; Gillings, Nic; Herth, Matthias M; Knudsen, Gitte M; Kristensen, Jesper L.

Bioorg Med Chem ; 24(21): 5353-5356, 2016 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-27624522

8.

(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis.

Denholt, Charlotte; Gillings, Nic.

J Labelled Comp Radiopharm ; 59(4): 171-4, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26923297

9.

BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.

Fisher, Patrick M; Holst, Klaus K; Adamsen, Dea; Klein, Anders Bue; Frokjaer, Vibe G; Jensen, Peter S; Svarer, Claus; Gillings, Nic; Baare, William F C; Mikkelsen, Jens D; Knudsen, Gitte M.

Hum Brain Mapp ; 36(1): 313-23, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25220079

10.

[(64) Cu]-labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice.

Schjoeth-Eskesen, Christina; Nielsen, Carsten Haagen; Heissel, Søren; Højrup, Peter; Hansen, Paul Robert; Gillings, Nic; Kjaer, Andreas.

J Labelled Comp Radiopharm ; 58(6): 227-33, 2015 May 30.

Artigo em Inglês | MEDLINE | ID: mdl-25906708

11.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Toyohara, Jun; Vugts, Danielle; Kiss, Oliver C; Todde, Sergio; Li, Xiang-Guo; Liu, Zhibo; Yang, Zhi; Gillings, Nic; Cazzola, Emiliano; Szymanski, Wiktor; Meulen, Nick van der; Reilly, Raymond; Taddei, Carlotta; Schirrmacher, Ralf; Li, Zijing; Lagebo, Yohannes Jorge; Bentaleb, Naoual; Souza Albernaz, Marta de; Lapi, Suzanne; Ramogida, Caterina; Mukherjee, Archana; Ajenjo, Javier; Deuther-Conrad, Winnie; Bourdeau, Cécile.

EJNMMI Radiopharm Chem ; 9(1): 42, 2024 May 16.

Artigo em Inglês | MEDLINE | ID: mdl-38753262

12.

Direct comparison of [(18) F]MH.MZ and [(18) F] altanserin for 5-HT2A receptor imaging with PET.

Hansen, Hanne D; Ettrup, Anders; Herth, Matthias M; Dyssegaard, Agnete; Ratner, Cecilia; Gillings, Nic; Knudsen, Gitte M.

Synapse ; 67(6): 328-37, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23390031

13.

Radiotracers for positron emission tomography imaging.

Gillings, Nic.

MAGMA ; 26(1): 149-58, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23242769

14.

5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans.

Fisher, Patrick M; Holst, Klaus K; Mc Mahon, Brenda; Haahr, Mette E; Madsen, Karine; Gillings, Nic; Baaré, William F; Jensen, Peter S; Knudsen, Gitte M.

Neuroimage ; 62(1): 130-6, 2012 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-22584237

15.

No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human.

Pinborg, Lars H; Feng, Ling; Haahr, Mette E; Gillings, Nic; Dyssegaard, Agnete; Madsen, Jacob; Svarer, Claus; Yndgaard, Stig; Kjaer, Troels W; Parsey, Ramin V; Hansen, Hanne D; Ettrup, Anders; Paulson, Olaf B; Knudsen, Gitte M.

Synapse ; 66(10): 880-4, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22730164

16.

[¹⁸F]FE-PE2I PET is a feasible alternative to [¹²³I]FP-CIT SPECT for dopamine transporter imaging in clinically uncertain parkinsonism.

Marner, Lisbeth; Korsholm, Kirsten; Anderberg, Lasse; Lonsdale, Markus N; Jensen, Mads Radmer; Brødsgaard, Eva; Denholt, Charlotte L; Gillings, Nic; Law, Ian; Friberg, Lars.

EJNMMI Res ; 12(1): 56, 2022 Sep 07.

Artigo em Inglês | MEDLINE | ID: mdl-36070114

17.

First-in-Humans PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using ¹⁸F-labeled Active-Site Inhibited Factor VII (¹⁸F-ASIS): Potential as Companion Diagnostic.

Loft, Mathias; Christensen, Camilla; Clausen, Malene M; Carlsen, Esben A; Hansen, Carsten P; Kroman, Niels; Langer, Seppo W; Høgdall, Claus; Madsen, Jacob; Gillings, Nic; Nielsen, Carsten H; Klausen, Thomas L; Holm, Søren; Loft, Annika; Berthelsen, Anne K; Kjaer, Andreas.

J Nucl Med ; 63(12): 1871-1879, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35589407

18.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Toyohara, Jun; Al-Qahtani, Mohammed; Huang, Ya-Yao; Cazzola, Emiliano; Todde, Sergio; Furumoto, Shozo; Mikolajczak, Renata; Decristoforo, Clemens; Gillings, Nic; Yang, Min; Reilly, Raymond; Duatti, Adriano; Denkova, Antonia; Schirrmacher, Ralf; Carlucci, Giuseppe; Seimbille, Yann; Liu, Zhaofei; Ellis, Beverley; Cornelissen, Bart T; Kopka, Klaus; Bernardes, Emerson.

EJNMMI Radiopharm Chem ; 7(1): 25, 2022 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-36182995

19.

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers.

Ettrup, Anders; Hansen, Martin; Santini, Martin A; Paine, James; Gillings, Nic; Palner, Mikael; Lehel, Szabolcs; Herth, Matthias M; Madsen, Jacob; Kristensen, Jesper; Begtrup, Mikael; Knudsen, Gitte M.

Eur J Nucl Med Mol Imaging ; 38(4): 681-93, 2011 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-21174090

20.

Fully Automated GMP-Compliant Synthesis of [¹⁸F]FE-PE2I.

Bratteby, Klas; Denholt, Charlotte Lund; Lehel, Szabolcs; Petersen, Ida Nymann; Madsen, Jacob; Erlandsson, Maria; Ohlsson, Tomas; Herth, Matthias Manfred; Gillings, Nic.

Pharmaceuticals (Basel) ; 14(7)2021 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-34206688

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EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials.

Stress Hormone Dynamics Are Coupled to Brain Serotonin 4 Receptor Availability in Unmedicated Patients With Major Depressive Disorder: A NeuroPharm Study.

EANM guideline on quality risk management for radiopharmaceuticals.

Serotonin 2A receptor agonist binding in the human brain with [(11)C]Cimbi-36: Test-retest reproducibility and head-to-head comparison with the antagonist [(18)F]altanserin.

The Center for Integrated Molecular Brain Imaging (Cimbi) database.

Metabolic Fate of Hallucinogenic NBOMes.

Convergent ¹⁸F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT_2A receptor PET ligands.

(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis.

BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.

[(64) Cu]-labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Direct comparison of [(18) F]MH.MZ and [(18) F] altanserin for 5-HT2A receptor imaging with PET.

Radiotracers for positron emission tomography imaging.

5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans.

No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human.

[¹⁸F]FE-PE2I PET is a feasible alternative to [¹²³I]FP-CIT SPECT for dopamine transporter imaging in clinically uncertain parkinsonism.

First-in-Humans PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using ¹⁸F-labeled Active-Site Inhibited Factor VII (¹⁸F-ASIS): Potential as Companion Diagnostic.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers.

Fully Automated GMP-Compliant Synthesis of [¹⁸F]FE-PE2I.