RESUMO
We report a case of Chromobacterium violaceum infection and we review the literature for all published cases. C. violaceum grew from a peritoneal fluid of a 47-year-old woman operated on for peritonitis following perforative gastroduodenal ulcer. She was just coming back from a 1-month-holyday in French Guyana, where she might have been in contact with this micro-organism. The patient fully recovered after surgical management associated with antibiotic therapy consisting of ofloxacin plus piperacillin-tazobactam. Among the more than a hundred of published cases of human infections with C. violaceum that we retrieved, there was not any other case of peritonitis.
Assuntos
Antibacterianos/uso terapêutico , Chromobacterium , Infecções por Bactérias Gram-Negativas/diagnóstico , Úlcera Péptica Perfurada/complicações , Úlcera Péptica Perfurada/cirurgia , Peritonite/microbiologia , Quimioterapia Combinada , Feminino , Infecções por Bactérias Gram-Negativas/tratamento farmacológico , Humanos , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
A review of the literature shows that the association of epidermolysis bullosa acquisita and Crohn's disease is rare. A 27-year-old man developed cutaneous blisters on the trauma-prone areas that were consistent with the diagnosis of epidermolysis bullosa acquisita. Immunological and electron-microscopic studies of the skin showed intense IgG deposits located beneath the basal lamina. Three years later, Crohn's colitis was diagnosed. Prednisolone and sulfasalazine treatment resulted in an improvement of the bowel disease but without appreciable effect on the skin lesions.
Assuntos
Doença de Crohn/complicações , Epidermólise Bolhosa/complicações , Adulto , Doença de Crohn/tratamento farmacológico , Epidermólise Bolhosa/patologia , Imunofluorescência , Humanos , Técnicas Imunoenzimáticas , Masculino , Microscopia Eletrônica , Prednisolona/uso terapêutico , Pele/ultraestrutura , Sulfassalazina/uso terapêuticoRESUMO
A case of gastric retention without outlet obstruction in a 44-year-old patient with esophageal carcinoma is reported. Radiological (and particularly C.T.) examinations support the opinion that the gastric motility disorders were due to the autovagotomy secondary to malignant involvement of the intrathoracic vagus nerve.
Assuntos
Carcinoma de Células Escamosas/complicações , Neoplasias Esofágicas/complicações , Síndromes de Compressão Nervosa/etiologia , Gastropatias/etiologia , Nervo Vago , Adulto , Transtornos de Deglutição/etiologia , Esvaziamento Gástrico , Humanos , Masculino , Neoplasias do Mediastino/secundárioRESUMO
The authors report a case of Campylobacter fetus subsp. fetus gastro-intestinal infection and bacteremia with poly-arthritis, mainly of the hip, in a French patient simultaneously suffering from cirrhosis of the liver. The outcome was eventually favorable, however only after a trial of ineffective pefloxacin-gentamicin therapy. The authors suggest: (i) gentamicin should not be given alone in C. fetus subsp. fetus infections, and (ii) pefloxacin should not be given if antibiotic sensitivities data are not available. The inconclusive reliability of disk diffusion tests for C. fetus subsp. fetus should be recognized.
Assuntos
Artrite Infecciosa/tratamento farmacológico , Bacteriemia/tratamento farmacológico , Infecções por Campylobacter/tratamento farmacológico , Campylobacter fetus/efeitos dos fármacos , Quimioterapia Combinada/administração & dosagem , Gastroenteropatias/tratamento farmacológico , Articulação do Quadril , Pefloxacina/administração & dosagem , Artrite Infecciosa/microbiologia , Bacteriemia/microbiologia , Infecções por Campylobacter/microbiologia , Resistência Microbiana a Medicamentos , Gastroenteropatias/microbiologia , Gentamicinas/administração & dosagem , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The authors report the case of a patient with chronic lymphocytic leukemia well controlled during five years, and then complicated with immunoblastic lymphoma of the ileo-caecal area. The tumor was revealed by a protein-rich peritoneal effusion containing numerous large undifferentiated lymphoid cells. Only five cases of Richter's syndrome, apparently localized to the digestive tract, have been published to date.
Assuntos
Ascite/etiologia , Neoplasias do Ceco/complicações , Neoplasias do Íleo/complicações , Leucemia Linfoide/complicações , Linfoma não Hodgkin/complicações , Neoplasias Primárias Múltiplas , Neoplasias do Ceco/patologia , Humanos , Neoplasias do Íleo/patologia , Leucemia Linfoide/patologia , Linfoma não Hodgkin/patologia , Masculino , Pessoa de Meia-Idade , SíndromeRESUMO
Collagenous colitis and microscopic colitis are histologic entities which do not have corresponding endoscopic features. Their precise incidence and role in the development of intestinal symptoms are poorly known. The aim of this study was to determine the frequency of these histologic abnormalities in patients with endoscopically normal colon and to correlate these findings with abdominal symptoms. Total colonoscopy was performed in 132 consecutive patients, 81 females and 51 males, aged 19 to 83 years (mean: 47.8 years). Patients complained of abdominal pain and/or diarrhea (66 cases), normal bowel transit or constipation (66 cases). Subjects were prepared for colonoscopy with polyethylene glycol 4,000. Three to 8 biopsies were taken from the rectum and the different parts of the colon. Histologic abnormalities were found in 36 patients (27.2 p. 100): collagenous colitis (7 cases), microscopic colitis (21 cases), and melanosis coli (8 cases). The frequency of diarrhea was significantly higher in patients with collagenous colitis and microscopic colitis than in those with melanosis coli or normal colonic mucosa. These results clearly demonstrate that routine biopsies of the rectum and colon are useful in patients with abdominal symptoms, particularly diarrhea, and normal endoscopy.
Assuntos
Colite/patologia , Doenças do Colágeno/patologia , Colo/patologia , Reto/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Colonoscopia , Feminino , Humanos , Mucosa Intestinal/patologia , Masculino , Pessoa de Meia-IdadeRESUMO
Thrombosis around a centrally-implanted catheter is a complication of this method of venous approach. Usually asymptomatic, it is normally detected by phlebography, histopathology or computed angiotomography. Thirty-five patients with catheters in internal jugular vein composed of silicone (13 cases) or polyurethane (22 cases) were followed up by velocimetric and echotomographic examinations before introduction and one and three weeks after introduction of a catheter, these exploratory procedures possessing the advantage of being rapid, repetable and non-invasive. Three thrombosis were diagnosed using this method, including two without clinical signs, one on a silicone and two a polyurethane catheter. This represents 8.6% of total population, comparable with results of phlebography and histopathology reported in the litterature. The echotomographic appearance of the fibrinoplatelet sleeve left by the catheter after its removal is also described. Combined velocimetric and echotomographic examination is an investigational method which is non-invasive, reliable, rapid and repeatable for evaluation of appearance, localization, extension and also follow up of thrombosis.
Assuntos
Cateteres de Demora/efeitos adversos , Monitorização Fisiológica/métodos , Reologia , Ultrassonografia/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Velocidade do Fluxo Sanguíneo , Feminino , Humanos , Veias Jugulares , Masculino , Pessoa de Meia-Idade , Trombose/diagnóstico , Trombose/etiologia , Fatores de TempoRESUMO
The authors report a case of uro-colonic tumour developing four years after ureterosigmoidostomy in a male patient treated for invasive bladder tumour. After a current follow-up of five years for this colonic tumour, they studied their case in comparison with the data from the literature and the experimental model in order to better understand the natural history of these tumours. The following principal points are discussed: time to onset, histological nature and course of these tumours; essential elements in this type of carcinogenesis, practical clinical implications and follow-up of patients after ureterosigmoidostomy.
Assuntos
Neoplasias do Colo/etiologia , Neoplasias da Bexiga Urinária/cirurgia , Derivação Urinária/efeitos adversos , Colo Sigmoide/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Ureter/cirurgiaRESUMO
Duodenogastric reflux of bile and pancreatic secretions is known to induce acute chronic alterations of gastric and oesophageal mucosa. Several complex methods have been reported to demonstrate duodenogastric reflux (DGR) in man. The aim of this work was to describe a simple test for evaluation of DGR. The studied groups included: 1) 30 patients with DGR demonstrated by the radiological test of Capper and by endoscopic examination (group I); 2) 18 subjects without demonstrable DGR (group II). Bilirubin concentrations were measured in gastric juice collected for 10 min periods during one hour before and one hour after gallbladder stimulation by cholecystokinin-pancreozymin (CCK-PZ) (35 Ivy-dog Units). Bilirubin output was determined in the basal state (basal bilirubin output); maximal bilirubin peak (MBP) was determined by the highest of the collected samples following CCK-PZ administration. There was no significant difference between the two groups for basal bilirubin output. Analysis of the MBP showed that the two groups were significantly different (p less than 0.05). A duodenogastric reflux is present and can be quantitated when the MBP is above 200 microgram. Our results suggest that this method is available to evaluate the role of duodenogastric influx in gastric and/or oesophageal diseases.