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1.
Nature ; 529(7586): 368-72, 2016 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-26760209

RESUMO

Although water vapour is the main species observed in the coma of comet 67P/Churyumov-Gerasimenko and water is the major constituent of cometary nuclei, limited evidence for exposed water-ice regions on the surface of the nucleus has been found so far. The absence of large regions of exposed water ice seems a common finding on the surfaces of many of the comets observed so far. The nucleus of 67P/Churyumov-Gerasimenko appears to be fairly uniformly coated with dark, dehydrated, refractory and organic-rich material. Here we report the identification at infrared wavelengths of water ice on two debris falls in the Imhotep region of the nucleus. The ice has been exposed on the walls of elevated structures and at the base of the walls. A quantitative derivation of the abundance of ice in these regions indicates the presence of millimetre-sized pure water-ice grains, considerably larger than in all previous observations. Although micrometre-sized water-ice grains are the usual result of vapour recondensation in ice-free layers, the occurrence of millimetre-sized grains of pure ice as observed in the Imhotep debris falls is best explained by grain growth by vapour diffusion in ice-rich layers, or by sintering. As a consequence of these processes, the nucleus can develop an extended and complex coating in which the outer dehydrated crust is superimposed on layers enriched in water ice. The stratigraphy observed on 67P/Churyumov-Gerasimenko is therefore the result of evolutionary processes affecting the uppermost metres of the nucleus and does not necessarily require a global layering to have occurred at the time of the comet's formation.


Assuntos
Meio Ambiente Extraterreno/química , Gelo/análise , Meteoroides , Difusão , Gases/análise , Gases/química , Análise Espectral
2.
Nature ; 525(7570): 500-3, 2015 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-26399830

RESUMO

Observations of cometary nuclei have revealed a very limited amount of surface water ice, which is insufficient to explain the observed water outgassing. This was clearly demonstrated on comet 9P/Tempel 1, where the dust jets (driven by volatiles) were only partially correlated with the exposed ice regions. The observations of 67P/Churyumov-Gerasimenko have revealed that activity has a diurnal variation in intensity arising from changing insolation conditions. It was previously concluded that water vapour was generated in ice-rich subsurface layers with a transport mechanism linked to solar illumination, but that has not hitherto been observed. Periodic condensations of water vapour very close to, or on, the surface were suggested to explain short-lived outbursts seen near sunrise on comet 9P/Tempel 1. Here we report observations of water ice on the surface of comet 67P/Churyumov-Gerasimenko, appearing and disappearing in a cyclic pattern that follows local illumination conditions, providing a source of localized activity. This water cycle appears to be an important process in the evolution of the comet, leading to cyclical modification of the relative abundance of water ice on its surface.


Assuntos
Meio Ambiente Extraterreno/química , Gelo/análise , Meteoroides , Temperatura , Fatores de Tempo , Volatilização
3.
ISA Trans ; 132: 167-181, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36404152

RESUMO

In recent aerospace missions, space logistics have proven essential in storing, delivering and returning crew and materials between terrestrial facilities and space stations. Unlike classical commercial logistics, space logistics operations are cost-prohibitive and mission-driven, and its replenishment cycle for essential materials is relatively long. Therefore, the complete utilisation of spacecraft payload is of utmost importance. The theory of the inventory packing problem is extended in this study to build autonomous agents that interact with one another within a space logistics decision support system to reinforce the replenishment decision, chunk loading optimisation, and quality inspection. With the long replenishment cycle time, an agent embedded with interval type-2 fuzzy logic is explored to support chaotic time-series demand forecasting to derive re-order quantities in the desired period. Afterwards, the second agent solves the space chunk loading problem using the differential evolution algorithm to utilise payloads and capacities, particularly cylindrical chunks fully. The third agent measures actual item dimensions and quality to deploy the three-dimensional object scanning devices. Feedback is provided to the second agent to derive optimal chunk-loading instructions. Thanks to the autonomous interactions among the above agents, mission-critical decisions for space logistics are supported to achieve operational excellence.

4.
J Healthc Eng ; 2021: 9974059, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34804463

RESUMO

Due to the global ageing population, the increasing demand for long-term care services for the elderly has directed considerable attention towards the renovation of nursing homes. Although nursing homes play an essential role within residential elderly care, professional shortages have created serious pressure on the elderly service sector. Effective workforce planning is vital for improving the efficacy and workload balance of existing nursing staff in today's complex and volatile long-term care service market. Currently, there is lack of an integrated solution to monitor care services and determine the optimal nursing staffing strategy in nursing homes. This study addresses the above challenge through the formulation of nursing staffing optimisation under the blockchain-internet of things (BIoT) environment. Embedding a blockchain into IoT establishes the long-term care platform for the elderly and care workers, thereby decentralising long-term care information in the nursing home network to achieve effective care service monitoring. Moreover, such information is further utilised to optimise nursing staffing by using a genetic algorithm. A case study of a Hong Kong nursing home was conducted to illustrate the effectiveness of the proposed system. We found that the total monthly staffing cost after using the proposed model was significantly lower than the existing practice with a change of -13.48%, which considers the use of heterogeneous workforce and temporary staff. Besides, the care monitoring and staffing flexibility are further enhanced, in which the concept of skill substitution is integrated in nursing staffing optimisation.


Assuntos
Blockchain , Assistência de Longa Duração , Idoso , Humanos , Casas de Saúde , Admissão e Escalonamento de Pessoal , Recursos Humanos
5.
Science ; 176(4037): 906-7, 1972 May 26.
Artigo em Inglês | MEDLINE | ID: mdl-17829299

RESUMO

The asteroid 1685 Toro has its perihelion inside the Earth's orbit and a period which is 8/ 5 of that of the Earth. A calculation of Toro's orbit covering 200 years shows that this asteroid at present is captured in resonance with the Earth. The capture is due to the gravitational interaction at close encounters between the bodies.

6.
Science ; 207(4429): 425-31, 1980 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-17833553

RESUMO

Pioneer 11 has made the first exploration of the magnetosphere and trapped radiation belts of Saturn. Saturn's magnetosphere is intermediate in size between Earth's and Jupiter's, with trapped particle intensities comparable to Earth's. The outer region of Saturn's magnetosphere contains lower energy radiation and is variable with time; the inner region contains higher energy particles. The pitch angle distributions show a remarkable variety of field-aligned and locally mirroring configurations. The moons and especially the rings of Saturn are effective absorbers of trapped particles; underneath the rings, the trapped radiation is completely absorbed. We confirm the discovery of a new ring, called the F ring, a new division, the Pioneer division, and a moon, called 1979 S 2. The latter has probably been seen from Earth. There may be evidence for more bodies like 1979 S 2, but at this stage the interpretation of the data is ambiguous. Using particle diffusion rates, we estimate that the cross-sectional area of the F ring is > 7 x 10(13) square centimeters and that the opacity is > 10(-5). Cosmic-ray albedo neutron decay should be looked into as a source of energetic particles in the inner magnetosphere of Saturn.

7.
Science ; 213(4515): 1493-5, 1981 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-17780879

RESUMO

Several recent developments have implications for the neutral particle environment of Jupiter. Very hot sulfur ions have been detected in the Io torus with gyrospeeds comparable to the corotation speed, a phenomenon that would result from a neutral sulfur cloud. Current evidence supports the hypothesis that extensive neutral clouds of oxygen and sulfur exist in the Jupiter magnetosphere and that they are important sources of ions and energy for the Io torus.

8.
Science ; 232(4748): 377-81, 1986 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-17792149

RESUMO

The plasma wave instrument on the International Cometary Explorer (ICE) detected bursts of strong ion acoustic waves almost continuously when the spacecraft was within 2 million kilometers of the nucleus of comet Giacobini-Zinner. Electromagnetic whistlers and low-level electron plasma oscillations were also observed in this vast region that appears to be associated with heavy ion pickup. As ICE came closer to the anticipated location of the bow shock, the electromagnetic and electrostatic wave levels increased significantly, but even in the midst of this turbulence the wave instrument detected structures with familiar bow shock characteristics that were well correlated with observations of localized electron heating phenomena. Just beyond the visible coma, broadband waves with amplitudes as high as any ever detected by the ICE plasma wave instrument were recorded. These waves may account for the significant electron heating observed in this region by the ICE plasma probe, and these observations of strong wave-particle interactions may provide answers to longstanding questions concerning ionization processes in the vicinity of the coma. Near closest approach, the plasma wave instrument detected broadband electrostatic noise and a changing pattern of weak electron plasma oscillations that yielded a density profile for the outer layers of the cold plasma tail. Near the tail axis the plasma wave instrument also detected a nonuniform flux of dust impacts, and a preliminary profile of the Giacobini-Zinner dust distribution for micrometer-sized particles is presented.

9.
Science ; 267(5202): 1317-20, 1995 Mar 03.
Artigo em Inglês | MEDLINE | ID: mdl-7871430

RESUMO

The electrodynamic interaction of the dust and gas comae of comet Shoemaker-Levy 9 with the jovian magnetosphere was unique and different from the atmospheric effects. Early theoretical predictions of auroral-type processes on the comet magnetic field line and advanced modeling of the time-varying morphology of these lines allowed dedicated observations with the Hubble Space Telescope Wide Field Planetary Camera 2 and resulted in the detection of a bright auroral spot. In that respect, this observation of the surface signature of an externally triggered auroral process can be considered as a "magnetospheric active experiment" on Jupiter.


Assuntos
Meio Ambiente Extraterreno , Júpiter , Sistema Solar , Magnetismo
10.
Science ; 362(6410)2018 10 05.
Artigo em Inglês | MEDLINE | ID: mdl-30287631

RESUMO

Saturn has a sufficiently strong dipole magnetic field to trap high-energy charged particles and form radiation belts, which have been observed outside its rings. Whether stable radiation belts exist near the planet and inward of the rings was previously unknown. The Cassini spacecraft's Magnetosphere Imaging Instrument obtained measurements of a radiation belt that lies just above Saturn's dense atmosphere and is decoupled from the rest of the magnetosphere by the planet's A- to C-rings. The belt extends across the D-ring and comprises protons produced through cosmic ray albedo neutron decay and multiple charge-exchange reactions. These protons are lost to atmospheric neutrals and D-ring dust. Strong proton depletions that map onto features on the D-ring indicate a highly structured and diverse dust environment near Saturn.

11.
Science ; 362(6410)2018 10 05.
Artigo em Inglês | MEDLINE | ID: mdl-30287634

RESUMO

The Pioneer and Voyager spacecraft made close-up measurements of Saturn's ionosphere and upper atmosphere in the 1970s and 1980s that suggested a chemical interaction between the rings and atmosphere. Exploring this interaction provides information on ring composition and the influence on Saturn's atmosphere from infalling material. The Cassini Ion Neutral Mass Spectrometer sampled in situ the region between the D ring and Saturn during the spacecraft's Grand Finale phase. We used these measurements to characterize the atmospheric structure and material influx from the rings. The atmospheric He/H2 ratio is 10 to 16%. Volatile compounds from the rings (methane; carbon monoxide and/or molecular nitrogen), as well as larger organic-bearing grains, are flowing inward at a rate of 4800 to 45,000 kilograms per second.

12.
Science ; 355(6332): 1392-1395, 2017 03 31.
Artigo em Inglês | MEDLINE | ID: mdl-28325842

RESUMO

The Rosetta spacecraft spent ~2 years orbiting comet 67P/Churyumov-Gerasimenko, most of it at distances that allowed surface characterization and monitoring at submeter scales. From December 2014 to June 2016, numerous localized changes were observed, which we attribute to cometary-specific weathering, erosion, and transient events driven by exposure to sunlight and other processes. While the localized changes suggest compositional or physical heterogeneity, their scale has not resulted in substantial alterations to the comet's landscape. This suggests that most of the major landforms were created early in the comet's current orbital configuration. They may even date from earlier if the comet had a larger volatile inventory, particularly of CO or CO2 ices, or contained amorphous ice, which could have triggered activity at greater distances from the Sun.

13.
Oncogene ; 35(24): 3178-89, 2016 06 16.
Artigo em Inglês | MEDLINE | ID: mdl-26477309

RESUMO

Human adenoviruses (HAdV) are used as a model system to investigate tumorigenic processes in mammalian cells where the viral oncoproteins E1A and E1B-55K are absolutely required for oncogenic transformation, because they simultaneously accelerate cell cycle progression and inhibit tumor suppressor proteins such as p53, although the underlying mechanism is still not understood in detail. In our present study, we provide evidence that E1B-55K binding to the PML-NB component Sp100A apparently has an essential role in regulating adenovirus-mediated transformation processes. Specifically, when this E1B-55K/Sp100A complex recruits p53, Sp100A-induced activation of p53 transcriptional activity is effectively abolished. Hence, Sp100A exhibits tumor-suppressive activity, not only by stabilizing p53 transactivation but also by depressing E1A/E1B-55K-mediated transformation. E1B-55K counteracts this suppressive activity, inducing Sp100A SUMOylation and sequestering the modified cellular factor into the insoluble matrix of the nucleus or into cytoplasmic inclusions. These observations provide novel insights into how E1B-55K modulates cellular determinants to maintain growth-promoting activity during oncogenic processes and lytic infection.


Assuntos
Proteínas E1B de Adenovirus/fisiologia , Antígenos Nucleares/metabolismo , Autoantígenos/metabolismo , Transformação Celular Viral/fisiologia , Proteína Supressora de Tumor p53/metabolismo , Proteínas E1B de Adenovirus/genética , Transformação Celular Viral/genética , Humanos , Fatores de Transcrição/metabolismo , Ativação Transcricional , Transfecção , Proteína Supressora de Tumor p53/genética
14.
Science ; 354(6319): 1563-1566, 2016 12 23.
Artigo em Inglês | MEDLINE | ID: mdl-27856846

RESUMO

Carbon dioxide (CO2) is one of the most abundant species in cometary nuclei, but because of its high volatility, CO2 ice is generally only found beneath the surface. We report the infrared spectroscopic identification of a CO2 ice-rich surface area located in the Anhur region of comet 67P/Churyumov-Gerasimenko. Spectral modeling shows that about 0.1% of the 80- by 60-meter area is CO2 ice. This exposed ice was observed a short time after the comet exited local winter; following the increased illumination, the CO2 ice completely disappeared over about 3 weeks. We estimate the mass of the sublimated CO2 ice and the depth of the eroded surface layer. We interpret the presence of CO2 ice as the result of the extreme seasonal changes induced by the rotation and orbit of the comet.

15.
Science ; 354(6319): 1566-1570, 2016 12 23.
Artigo em Inglês | MEDLINE | ID: mdl-27856849

RESUMO

The Rosetta spacecraft has investigated comet 67P/Churyumov-Gerasimenko from large heliocentric distances to its perihelion passage and beyond. We trace the seasonal and diurnal evolution of the colors of the 67P nucleus, finding changes driven by sublimation and recondensation of water ice. The whole nucleus became relatively bluer near perihelion, as increasing activity removed the surface dust, implying that water ice is widespread underneath the surface. We identified large (1500 square meters) ice-rich patches appearing and then vanishing in about 10 days, indicating small-scale heterogeneities on the nucleus. Thin frosts sublimating in a few minutes are observed close to receding shadows, and rapid variations in color are seen on extended areas close to the terminator. These cyclic processes are widespread and lead to continuously, slightly varying surface properties.

16.
Science ; 347(6220): aaa0628, 2015 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-25613895

RESUMO

The VIRTIS (Visible, Infrared and Thermal Imaging Spectrometer) instrument on board the Rosetta spacecraft has provided evidence of carbon-bearing compounds on the nucleus of the comet 67P/Churyumov-Gerasimenko. The very low reflectance of the nucleus (normal albedo of 0.060 ± 0.003 at 0.55 micrometers), the spectral slopes in visible and infrared ranges (5 to 25 and 1.5 to 5% kÅ(-1)), and the broad absorption feature in the 2.9-to-3.6-micrometer range present across the entire illuminated surface are compatible with opaque minerals associated with nonvolatile organic macromolecular materials: a complex mixture of various types of carbon-hydrogen and/or oxygen-hydrogen chemical groups, with little contribution of nitrogen-hydrogen groups. In active areas, the changes in spectral slope and absorption feature width may suggest small amounts of water-ice. However, no ice-rich patches are observed, indicating a generally dehydrated nature for the surface currently illuminated by the Sun.

17.
J Am Soc Mass Spectrom ; 13(12): 1396-406, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12484459

RESUMO

This paper describes our effort in optimizing the experimental parameters for electron capture dissociation (ECD) of peptides in a commercially available Fourier-transform mass spectrometer. Using a built-in electrically heated filament electron gun, it was demonstrated that good quality ECD spectra of peptides (MW < 2500) could be obtained by irradiating the isolated peptide molecule-ions with a short pulse (50 ms) of low-energy (3-6 eV) electrons. In addition, we have also demonstrated that pulsing of inert cooling gas (argon) could further improve the intensity of the ECD-induced fragment ions. Due presumably to the influence of the strong magnetic field on the trajectories of electrons, the distance between the electron gun and the trapped-ion cell (i.e., 108 mm versus 20 mm) was found to have little influence on the efficiency of the ECD process(es). From a systematic study on the impact of the filament heating current, filament bias voltage, and electron irradiation time on the intensities of precursor ions and various fragment ions, it was postulated that subsequent capture of electrons by the fragment ions, i.e., neutralization of the fragment ions, might be a significant event for limiting the intensity of the fragment ions.


Assuntos
Peptídeos/química , Sequência de Aminoácidos , Ciclotrons , Elétrons , Análise de Fourier , Dados de Sequência Molecular , Espectrometria de Massas por Ionização por Electrospray
18.
Phys Rev E Stat Nonlin Soft Matter Phys ; 84(4 Pt 2): 046413, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22181289

RESUMO

Kelvin-Helmholtz instability (KHI) driven by velocity shear is a generator of waves found away from the vicinity of the velocity-shear layers since the fast-mode waves radiated from the surface perturbation can propagate away from the transition layer. Thus the nonlinear evolution associated with KHI is not confined near the velocity-shear layer. To understand the physical processes in multiple velocity-shear layers, the interactions between two KHIs at a pair of tangential discontinuities are studied by two-dimensional magnetohydrodynamic simulations. It is shown that the interactions between two neighboring velocity-shear layers are dominated by the propagation of the fast-mode waves radiated from KHIs in a nonuniform medium. That is, the fast-mode Mach number of the surface waves M(Fy), a key factor of the nonlinear evolution of KHI, will vary with the nonuniform background plasma velocity due to the existence of two neighboring velocity-shear layers. As long as the M(Fy) observed in the plasma rest frame across the neighboring velocity-shear layer is larger than one, newly formed fast-mode Mach-cone-like (MCL) plane waves generated by the fast-mode waves can be found in this region. As results of the interactions of two KHIs, reflection and distortion of the MCL plane waves generate the turbulence and increase the plasma temperature, which provide possible mechanisms of heating and accelerating local plasma between two neighboring velocity-shear layers.

19.
Science ; 334(6055): 492-4, 2011 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-22034430

RESUMO

The Visible, InfraRed, and Thermal Imaging Spectrometer (VIRTIS) on Rosetta obtained hyperspectral images, spectral reflectance maps, and temperature maps of the asteroid 21 Lutetia. No absorption features, of either silicates or hydrated minerals, have been detected across the observed area in the spectral range from 0.4 to 3.5 micrometers. The surface temperature reaches a maximum value of 245 kelvin and correlates well with topographic features. The thermal inertia is in the range from 20 to 30 joules meter(-2) kelvin(-1) second(-0.5), comparable to a lunarlike powdery regolith. Spectral signatures of surface alteration, resulting from space weathering, seem to be missing. Lutetia is likely a remnant of the primordial planetesimal population, unaltered by differentiation processes and composed of chondritic materials of enstatitic or carbonaceous origin, dominated by iron-poor minerals that have not suffered aqueous alteration.

20.
Science ; 327(5962): 190-3, 2010 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-20056887

RESUMO

The European Space Agency's Rosetta mission encountered the main-belt asteroid (2867) Steins while on its way to rendezvous with comet 67P/Churyumov-Gerasimenko. Images taken with the OSIRIS (optical, spectroscopic, and infrared remote( )imaging system) cameras on board Rosetta show that Steins is an oblate body with an effective spherical diameter of 5.3 kilometers. Its surface does not show color variations. The morphology of Steins is dominated by linear faults and a large 2.1-kilometer-diameter crater near its south pole. Crater counts reveal a distinct lack of small craters. Steins is not solid rock but a rubble pile and has a conical appearance that is probably the result of reshaping due to Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) spin-up. The OSIRIS images constitute direct evidence for the YORP effect on a main-belt asteroid.

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