1.
Chem Commun (Camb)
; 51(2): 413-6, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25406914
RESUMO
A hybrid comprising an autophagy-inducing peptide (AIP) and a cell-penetrating peptide (CPP) connected via heterodimeric leucine zippers was generated and delivered into cells. The hybrid successfully induced autophagy without significant cell death, while the same AIP directly connected to a CPP caused both autophagy and significant cell death.