Detalhe da pesquisa
1.
TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.
Mol Ther
; 32(2): 325-339, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38053332
2.
Cryptic resolution sites in the vector plasmid lead to the heterogeneities in the rAAV vectors.
J Med Virol
; 95(1): e28433, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36571262
3.
BPEI-Induced Delocalization of PBP4 Potentiates ß-Lactams against MRSA.
Biochemistry
; 58(36): 3813-3822, 2019 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31429286
4.
Antibiofilm Synergy of ß-Lactams and Branched Polyethylenimine against Methicillin-Resistant Staphylococcus epidermidis.
Biomacromolecules
; 20(10): 3778-3785, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31430130
5.
B cell focused transient immune suppression protocol for efficient AAV readministration to the liver.
Mol Ther Methods Clin Dev
; 32(1): 101216, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38440160
6.
A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR.
Mol Ther Methods Clin Dev
; 32(1): 101206, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38390555
7.
Dimerization of 600 Da branched polyethylenimine improves ß-lactam antibiotic potentiation against antibiotic-resistant Staphylococcus epidermidis and Pseudomonas aeruginosa.
Chem Biol Drug Des
; 101(3): 489-499, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923750
8.
Breaking membrane barriers to neutralize E. coli and K. pneumoniae virulence with PEGylated branched polyethylenimine.
Biochim Biophys Acta Biomembr
; 1865(6): 184172, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37201561
9.
Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.
Sci Rep
; 13(1): 8436, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37231038
10.
ß Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk.
bioRxiv
; 2023 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398133
11.
Comprehensive Comparison of AAV Purification Methods: Iodixanol Gradient Centrifugation vs. Immuno-Affinity Chromatography.
Adv Cell Gene Ther
; 20232023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38130431
12.
Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS.
Mol Ther Methods Clin Dev
; 27: 185-194, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36284765
13.
Genomic Designs of rAAVs Contribute to Pathological Changes in the Livers and Spleens of Mice.
Adv Cell Gene Ther
; 20222022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507314
14.
Subgenomic particles in rAAV vectors result from DNA lesion/break and non-homologous end joining of vector genomes.
Mol Ther Nucleic Acids
; 29: 852-861, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36159586
15.
Chemical Modifications of the Capsid for Redirecting and Improving the Efficacy of Adeno-Associated Virus Vectors.
Hum Gene Ther
; 32(23-24): 1433-1438, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254844
16.
Dual-Function Potentiation by PEG-BPEI Restores Activity of Carbapenems and Penicillins against Carbapenem-Resistant Enterobacteriaceae.
ACS Infect Dis
; 7(6): 1657-1665, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33945257
17.
Low-Molecular-Weight Branched Polyethylenimine Potentiates Ampicillin against MRSA Biofilms.
ACS Med Chem Lett
; 11(4): 473-478, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292552
18.
Overcoming Multidrug Resistance and Biofilms of Pseudomonas aeruginosa with a Single Dual-Function Potentiator of ß-Lactams.
ACS Infect Dis
; 6(5): 1085-1097, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32223216
19.
Expanding the Spectrum of Antibiotics Capable of Killing Multidrug-Resistant Staphylococcus aureus and Pseudomonas aeruginosa.
ChemMedChem
; 15(15): 1421-1428, 2020 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32497366
20.
PEGylation of Polyethylenimine Lowers Acute Toxicity while Retaining Anti-Biofilm and ß-Lactam Potentiation Properties against Antibiotic-Resistant Pathogens.
ACS Omega
; 5(40): 26262-26270, 2020 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33073153