Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 164
Filtrar
Mais filtros

Base de dados
País/Região como assunto
Tipo de documento
Intervalo de ano de publicação
1.
Phys Rev Lett ; 131(5): 052501, 2023 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-37595245

RESUMO

We used the ^{138}Ba(d,α) reaction to carry out an in-depth study of states in ^{136}Cs, up to around 2.5 MeV. In this Letter, we place emphasis on hitherto unobserved states below the first 1^{+} level, which are important in the context of solar neutrino and fermionic dark matter (FDM) detection in large-scale xenon-based experiments. We identify for the first time candidate metastable states in ^{136}Cs, which would allow a real-time detection of solar neutrino and FDM events in xenon detectors, with high background suppression. Our results are also compared with shell-model calculations performed with three Hamiltonians that were previously used to evaluate the nuclear matrix element (NME) for ^{136}Xe neutrinoless double beta decay. We find that one of these Hamiltonians, which also systematically underestimates the NME compared with the others, dramatically fails to describe the observed low-energy ^{136}Cs spectrum, while the other two show reasonably good agreement.

2.
Phys Rev Lett ; 130(12): 122502, 2023 Mar 24.
Artigo em Inglês | MEDLINE | ID: mdl-37027859

RESUMO

The excited states of N=44 ^{74}Zn were investigated via γ-ray spectroscopy following ^{74}Cu ß decay. By exploiting γ-γ angular correlation analysis, the 2_{2}^{+}, 3_{1}^{+}, 0_{2}^{+}, and 2_{3}^{+} states in ^{74}Zn were firmly established. The γ-ray branching and E2/M1 mixing ratios for transitions deexciting the 2_{2}^{+}, 3_{1}^{+}, and 2_{3}^{+} states were measured, allowing for the extraction of relative B(E2) values. In particular, the 2_{3}^{+}→0_{2}^{+} and 2_{3}^{+}→4_{1}^{+} transitions were observed for the first time. The results show excellent agreement with new microscopic large-scale shell-model calculations, and are discussed in terms of underlying shapes, as well as the role of neutron excitations across the N=40 gap. Enhanced axial shape asymmetry (triaxiality) is suggested to characterize ^{74}Zn in its ground state. Furthermore, an excited K=0 band with a significantly larger softness in its shape is identified. A shore of the N=40 "island of inversion" appears to manifest above Z=26, previously thought as its northern limit in the chart of the nuclides.

3.
Phys Rev Lett ; 128(20): 202502, 2022 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-35657880

RESUMO

The electroweak interaction in the standard model is described by a pure vector-axial-vector structure, though any Lorentz-invariant component could contribute. In this Letter, we present the most precise measurement of tensor currents in the low-energy regime by examining the ß-ν[over ¯] correlation of trapped ^{8}Li ions with the Beta-decay Paul Trap. We find a_{ßν}=-0.3325±0.0013_{stat}±0.0019_{syst} at 1σ for the case of coupling to right-handed neutrinos (C_{T}=-C_{T}^{'}), which is consistent with the standard model prediction.

4.
Phys Rev Lett ; 126(2): 021803, 2021 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-33512206

RESUMO

Sterile neutrinos are natural extensions to the standard model of particle physics and provide a possible portal to the dark sector. We report a new search for the existence of sub-MeV sterile neutrinos using the decay-momentum reconstruction technique in the decay of ^{7}Be. The experiment measures the total energy of the ^{7}Li daughter atom from the electron capture decay of ^{7}Be implanted into sensitive superconducting tunnel junction (STJ) quantum sensors. This first experiment presents data from a single STJ operated at a low count rate for a net total of 28 days, and provides exclusion limits on sterile neutrinos in the mass range from 100 to 850 keV that improve upon previous work by up to an order of magnitude.

5.
J Dairy Sci ; 104(8): 9063-9081, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33934854

RESUMO

Selective use of antibiotic dry cow treatment can be implemented at the cow or quarter level, with the latter having the potential to further reduce antibiotic use. Our objective was to compare these 2 approaches in 6 herds in the United Kingdom in which environmental mastitis predominated. Eight hundred seven cows were enrolled and categorized as having a high cell count (n = 401) or low cell count (n = 406) in the last 3 mo of lactation and clinical mastitis history. All quarters of all enrolled cows received an internal teat sealant. Within each category, cows were randomly allocated to 1 of 3 groups; in one group antibiotic treatment was allocated at cow level (i.e., all 4 quarters received antibiotic), whereas in the 2 remaining groups antibiotic treatment was allocated at quarter level, based on California Mastitis Test (CMT) findings. Two different thresholds, score 1 and 2, were used to determine likely infection status. Quarter milk samples were collected at dry off and postcalving for bacteriological culture and somatic cell count (SCC). Cows were monitored for clinical mastitis from dry off until 100 d in milk. Cow level SCC and milk yield data were collated from farm records. Within each category, the 2 quarter level treatment groups were compared with cow level treatment at dry off. Leaving quarters untreated with intramammary antibiotic in cows in the high cell count group, with a CMT <2 or <1, reduced antibiotic use by 55% and 31%, respectively, and resulted in no difference in the odds of being infected with any pathogen postcalving, but was associated with a higher SCC at the first test day. Intramammary antibiotic treatment of quarters with a CMT ≥1 in cows in the low cell count category at dry off was not associated with any reduction in the odds of being infected with a major pathogen postcalving but was associated with a decrease in the odds of being infected with a minor mastitis pathogen postcalving. The use of antibiotics in quarters of cows categorized as low cell count at dry off, increased the proportion of quarters treated with antibiotic from 0% at cow level to 31% (CMT ≥ 1) and 12% (CMT ≥ 2) at quarter level, only resulting in a reduction in SCC of around 20,000 cells/mL at the first test day, if all quarters with CMT score ≥1 were treated with antibiotic. No differences in clinical mastitis incidence and milk yield in the first 100 d in milk were detected between any of the treatment groups. These study findings support selective quarter level dry off treatment only in cows with cow level SCC >200,000 cells/mL at dry off.


Assuntos
Doenças dos Bovinos , Mastite Bovina , Mastite , Animais , Antibacterianos/uso terapêutico , California , Bovinos , Doenças dos Bovinos/tratamento farmacológico , Contagem de Células/veterinária , Feminino , Lactação , Glândulas Mamárias Animais , Mastite/tratamento farmacológico , Mastite/veterinária , Mastite Bovina/tratamento farmacológico , Leite , Reino Unido
6.
Phys Rev Lett ; 125(3): 032701, 2020 Jul 17.
Artigo em Inglês | MEDLINE | ID: mdl-32745397

RESUMO

We report a high-statistics measurement of the L/K orbital electron capture ratio in ^{7}Be embedded in cryogenic Ta. The thin Ta film formed part of a high-resolution superconducting tunnel junction radiation detector that was used to identify the signals from different decay channels. The measured L/K capture ratio of 0.070(7) is significantly larger than the only previous measurement of this quantity and the theoretical predictions that include in-medium effects. This value is a uniquely sensitive probe of the 1s and 2s orbital overlaps with the nucleus and is of relevance to nuclear and atomic physics, as well as Li production in novae and other astrophysical scenarios. This is the first experiment that uses superconducting tunnel junctions for nuclear-recoil detection, opening a new experimental avenue for low-energy precision measurements with rare isotopes.

8.
Phys Rev Lett ; 125(17): 172501, 2020 Oct 23.
Artigo em Inglês | MEDLINE | ID: mdl-33156683

RESUMO

The ^{80}Ge structure was investigated in a high-statistics ß-decay experiment of ^{80}Ga using the GRIFFIN spectrometer at TRIUMF-ISAC through γ, ß-e, e-γ, and γ-γ spectroscopy. No evidence was found for the recently reported 0_{2}^{+} 639-keV level suggested as evidence for low-energy shape coexistence in ^{80}Ge. Large-scale shell model calculations performed in ^{78,80,82}Ge place the 0_{2}^{+} level in ^{80}Ge at 2 MeV. The new experimental evidence combined with shell model predictions indicate that low-energy shape coexistence is not present in ^{80}Ge.

9.
Phys Rev Lett ; 123(8): 082501, 2019 Aug 23.
Artigo em Inglês | MEDLINE | ID: mdl-31491233

RESUMO

The elusive ß^{-}p^{+} decay was observed in ^{11}Be by directly measuring the emitted protons and their energy distribution for the first time with the prototype Active Target Time Projection Chamber in an experiment performed at ISAC-TRIUMF. The measured ß^{-}p^{+} branching ratio is orders of magnitude larger than any previous theoretical model predicted. This can be explained by the presence of a narrow resonance in ^{11}B above the proton separation energy.

10.
Phys Rev Lett ; 123(14): 142502, 2019 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-31702191

RESUMO

From detailed spectroscopy of ^{110}Cd and ^{112}Cd following the ß^{+}/electron-capture decay of ^{110,112}In and the ß^{-} decay of ^{112}Ag, very weak decay branches from nonyrast states are observed. The transition rates determined from the measured branching ratios and level lifetimes obtained with the Doppler-shift attenuation method following inelastic neutron scattering reveal collective enhancements that are suggestive of a series of rotational bands. In ^{110}Cd, a γ band built on the shape-coexisting intruder configuration is suggested. For ^{112}Cd, the 2^{+} and 3^{+} intruder γ-band members are suggested, the 0_{3}^{+} band is extended to spin 4^{+}, and the 0_{4}^{+} band is identified. The results are interpreted using beyond-mean-field calculations employing the symmetry conserving configuration mixing method with the Gogny D1S energy density functional and with the suggestion that the Cd isotopes exhibit multiple shape coexistence.

11.
Phys Rev Lett ; 120(6): 062503, 2018 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-29481255

RESUMO

A precision mass investigation of the neutron-rich titanium isotopes ^{51-55}Ti was performed at TRIUMF's Ion Trap for Atomic and Nuclear science (TITAN). The range of the measurements covers the N=32 shell closure, and the overall uncertainties of the ^{52-55}Ti mass values were significantly reduced. Our results conclusively establish the existence of the weak shell effect at N=32, narrowing down the abrupt onset of this shell closure. Our data were compared with state-of-the-art ab initio shell model calculations which, despite very successfully describing where the N=32 shell gap is strong, overpredict its strength and extent in titanium and heavier isotones. These measurements also represent the first scientific results of TITAN using the newly commissioned multiple-reflection time-of-flight mass spectrometer, substantiated by independent measurements from TITAN's Penning trap mass spectrometer.

12.
Phys Rev Lett ; 113(8): 082502, 2014 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-25192092

RESUMO

In this Letter, we introduce the concept of in-trap nuclear decay spectroscopy of highly charged radioactive ions and describe its successful application as a novel spectroscopic tool. This is demonstrated by a measurement of the decay properties of radioactive mass A=124 ions (here, ^{124}In and ^{124}Cs) in the electron-beam ion trap of the TITAN facility at TRIUMF. By subjecting the trapped ions to an intense electron beam, the ions are charge bred to high charge states (i.e., equivalent to the removal of N-shell electrons), and an increase of storage times to the level of minutes without significant ion losses is achieved. The present technique opens the venue for precision spectroscopy of low branching ratios and is being developed in the context of measuring electron-capture branching ratios needed for determining the nuclear ground-state properties of the intermediate odd-odd nuclei in double-beta (ßß) decay.

13.
Phys Rev Lett ; 113(8): 082501, 2014 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-25192091

RESUMO

Using the Penning trap mass spectrometer TITAN, we performed the first direct mass measurements of (20,21)Mg, isotopes that are the most proton-rich members of the A = 20 and A = 21 isospin multiplets. These measurements were possible through the use of a unique ion-guide laser ion source, a development that suppressed isobaric contamination by 6 orders of magnitude. Compared to the latest atomic mass evaluation, we find that the mass of (21)Mg is in good agreement but that the mass of (20)Mg deviates by 3 σ. These measurements reduce the uncertainties in the masses of (20,21)Mg by 15 and 22 times, respectively, resulting in a significant departure from the expected behavior of the isobaric multiplet mass equation in both the A = 20 and A = 21 multiplets. This presents a challenge to shell model calculations using either the isospin nonconserving universal sd USDA and USDB Hamiltonians or isospin nonconserving interactions based on chiral two- and three-nucleon forces.

14.
Phys Rev Lett ; 110(2): 022504, 2013 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-23383898

RESUMO

Based on results from a measurement of weak decay branches observed following the ß- decay of 94Y and on lifetime data from a study of 94Zr by inelastic neutron scattering, collective structure is deduced in the closed-subshell nucleus 94Zr. These results establish shape coexistence in 94Zr. The role of subshells for nuclear collectivity is suggested to be important.

15.
J Dairy Sci ; 95(6): 2946-54, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22612932

RESUMO

Lameness in dairy cattle remains a significant welfare concern for the UK dairy industry. Farms were recruited into a 3-yr study evaluating novel intervention approaches designed to encourage farmers to implement husbandry changes targeted toward reducing lameness. All farms completing the study were visited at least annually and received either monitoring only (MO, n=72) or monitoring and additional support (MS, n = 117) from the research team. The additional support included traditional technical advice on farm-specific solutions, facilitation techniques to encourage farmer participation, and application of social marketing principles to promote implementation of change. Lameness prevalence was lower in the MO (27.0 ± 1.94 SEM) and MS (21.4 ± 1.28) farms at the final visit compared with the same MO (38.9 ± 2.06) and MS (33.3 ± 1.76) farms on the initial visit. After accounting for initial lameness, intervention group status, and year of visit within a multilevel model, we observed an interaction between year and provision of support, with the reduction in lameness over time being greater in the MS group compared with the MO group. Farms in the MS group made a greater number of changes to their husbandry practices over the duration of the project (8.2 ± 0.39) compared with those farms in the MO group (6.5 ± 0.54). Because the lameness prevalence was lower in the MS group than the MO group at the start of the study, the contribution of the additional support was difficult to define. Lameness can be reduced on UK dairy farms although further work is needed to identify the optimum approaches.


Assuntos
Criação de Animais Domésticos/métodos , Doenças dos Bovinos/prevenção & controle , Coxeadura Animal/prevenção & controle , Animais , Bovinos , Doenças dos Bovinos/epidemiologia , Coxeadura Animal/epidemiologia , Prevalência , Avaliação de Programas e Projetos de Saúde , Reino Unido/epidemiologia
16.
Phys Rev Lett ; 106(3): 032501, 2011 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-21405268

RESUMO

A high-precision half-life measurement for the superallowed ß+ emitter 26Al(m) was performed at the TRIUMF-ISAC radioactive ion beam facility yielding T 1/2 6346.54 ± 0.46(stat) ± 0.60 (syst) ms, consistent with, but 2.5 times more precise than, the previous world average. The 26Al(m) half-life and ft value, 3037.53(61) s, are now the most precisely determined for any superallowed ß decay. Combined with recent theoretical corrections for isospin-symmetry-breaking and radiative effects, the corrected Ft value for (26)Al(m), 3073.0(12) s, sets a new benchmark for the high-precision superallowed Fermi ß-decay studies used to test the conserved vector current hypothesis and determine the V(ud) element of the Cabibbo-Kobayashi-Maskawa quark mixing matrix.


Assuntos
Alumínio/química , Partículas beta , Radioisótopos/química , Meia-Vida
17.
J Dairy Sci ; 93(3): 932-41, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20172213

RESUMO

Visits were made to 205 dairy farms in England and Wales between October 2006 and May 2007 by 1 or more of 4 researchers. At each visit, all milking cows were locomotion scored (lameness scored) using a 4-point scale (0=sound locomotion, 1=imperfect locomotion, 2=lame, 3=severely lame). The mean prevalence of lameness (scores 2 and 3) across the study farms was 36.8% (range=0-79.2%). On each farm, the presence within the housing and grazing environments of commonly reported risks for increased lameness was recorded. Each farmer was interviewed to gauge the ability of the farm staff to detect and treat lameness. A multivariable linear regression model was fitted. Risk factors for increased lameness were the presence of damaged concrete in yards, cows pushing each other or turning sharply near the parlor entrance or exit, cattle grazing pasture also grazed by sheep, the use of automatic scrapers, not treating lame cows within 48h of detection, and cows being housed for 61 d or longer at the time they were locomotion scored by the visiting researcher. Having a herd consisting entirely of a breed or breeds other than Holstein-Friesian was associated with a reduction in lameness prevalence compared with having a herd consisting entirely of Holstein-Friesians.


Assuntos
Doenças dos Bovinos/epidemiologia , Indústria de Laticínios/métodos , Coxeadura Animal/epidemiologia , Animais , Bovinos , Inglaterra , Feminino , Abrigo para Animais/normas , Modelos Lineares , Prevalência , Fatores de Risco , Índice de Gravidade de Doença , País de Gales
18.
J Dairy Sci ; 93(5): 1970-8, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20412910

RESUMO

Evaluating the prevalence of lameness within herds of dairy cattle is important for management and certification purposes; however, sampling strategies that could reduce the time taken for an assessment would be valuable. The prevalence of lame and severely lame cows on 224 United Kingdom dairy farms was available for analysis. Presence of more than 1 severely lame cow on a farm was a useful indication of a lameness problem. The vast majority (80%) of the 182 farms that had > or = 1 severely lame cow present had an overall lameness prevalence >25%, whereas only 24% of the 42 farms that had no severely lame cows had an overall prevalence >25%. Information was available on individual milking order through the parlor on the day of the lameness assessment. On 37 farms where cows were housed in a group, lameness prevalence was 11.9% greater in the last third compared with the first third of the milking order. For 36 herds that were larger than 100 cows, sampling a maximum of 100 cows from the middle of the milking order produced an estimate of prevalence within 5% of the true prevalence on 83% of farms. A reasonable sampling strategy may, therefore, be to observe up to 100 cows from the middle of the milking order. Also, presence of severely lame cows at the end of milking may be useful for identifying those farms likely to benefit from further support.


Assuntos
Monitoramento Ambiental/métodos , Coxeadura Animal/epidemiologia , Animais , Bovinos , Indústria de Laticínios , Inglaterra/epidemiologia , Monitoramento Epidemiológico , Feminino , Abrigo para Animais , Densidade Demográfica , Prevalência , Fatores de Risco , Tamanho da Amostra , País de Gales/epidemiologia
19.
J Cell Biol ; 109(2): 697-704, 1989 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2668303

RESUMO

We have used immunocytofluorescence techniques to determine the subcellular distribution of the Ca2+, phospholipid-dependent protein kinase, protein kinase C (PKC). Using monoclonal antibodies that are specific for Type 3 (alpha) PKC, we have determined that there are least two pools of PKC in normal rat embryo fibroblasts (REF52 cells): diffuse cytoplasmic and fiber-associated. Extraction with chelators and detergent before fixing and staining removes the cytoplasmic PKC. The fiber-associated staining remains in these cytoskeleton preparations. The cytoskeleton Type 3 PKC staining closely resembles that of the focal contact protein vinculin and colocalizes with another focal contact protein, talin. Cytochalasin, but not colchicine, coordinately disrupts the staining pattern of vinculin and PKC. Activation of PKC by treatment with phorbol esters causes depolymerization of microfilaments and reorganization of vinculin staining. We propose that Type 3 PKC is a modulatory component of the focal contact and has a primary role in regulation of the association of microfilament bundles with the plasma membrane.


Assuntos
Citoesqueleto/metabolismo , Embrião de Mamíferos/citologia , Fibroblastos/metabolismo , Proteína Quinase C/metabolismo , Citoesqueleto de Actina/efeitos dos fármacos , Citoesqueleto de Actina/metabolismo , Citoesqueleto de Actina/ultraestrutura , Animais , Anticorpos Monoclonais/imunologia , Membrana Celular/efeitos dos fármacos , Membrana Celular/metabolismo , Membrana Celular/ultraestrutura , Células Cultivadas , Colchicina/farmacologia , Citocalasina B/farmacologia , Proteínas do Citoesqueleto/metabolismo , Citoesqueleto/efeitos dos fármacos , Citoesqueleto/ultraestrutura , Embrião de Mamíferos/metabolismo , Fibroblastos/citologia , Fibroblastos/ultraestrutura , Imunofluorescência , Imuno-Histoquímica , Isoenzimas/imunologia , Isoenzimas/metabolismo , Dibutirato de 12,13-Forbol/farmacologia , Fosforilação , Proteína Quinase C/imunologia , Ratos
20.
J Cell Biol ; 109(2): 685-95, 1989 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2668302

RESUMO

We have examined the immunocytochemical localization of protein kinase C (PKC) in NIH 3T3 cells using mAbs that recognize Type 3 PKC. In control cells, the immunofluorescent staining was similar with mAbs directed to either the catalytic or the regulatory domain of PKC. Type 3 PKC localized in a diffuse cytoplasmic pattern, while the nuclei were apparently unstained. Cytoskeletal components also were Treatment of the cells with phorbol 12-myristate 13-acetate (PMA) resulted in a redistribution of PKC with a specific increase in nuclear PKC. Compared to control cells, the staining with the anticatalytic domain mAbs changed markedly, covering the entire cell surface. In contrast, the staining by the antiregulatory domain mAb did not cover the cell surface and the nuclei remained unstained; these results suggest that PKC activation leads to a conformational change of the regulatory domain such that the epitope recognized by the antiregulatory domain mAb is not readily accessible. We have demonstrated by three criteria that PMA treatment specifically increased PKC in the nucleus: (a) immunofluorescent staining in isolated nuclei increased; (b) Western blots showed that our mAbs detected only one protein, the 82-kD PKC, whose level increased in nuclear lysates from PMA-treated cells; and (c) PKC activity increased in nuclear lysates. In fractionation studies we demonstrated that PKC specifically localized to the nuclear envelope fraction. These results demonstrate that PMA activation leads to a rapid redistribution of Type 3 PKC to the nuclear envelope, and suggests that this isozyme may play a role in mediating PKC-induced changes in gene expression.


Assuntos
Fibroblastos/enzimologia , Membrana Nuclear/enzimologia , Ésteres de Forbol/farmacologia , Proteína Quinase C/metabolismo , Animais , Anticorpos Monoclonais , Fracionamento Celular , Linhagem Celular , Citoesqueleto/enzimologia , Citoesqueleto/ultraestrutura , Fibroblastos/efeitos dos fármacos , Fibroblastos/ultraestrutura , Imunofluorescência , Isoenzimas/imunologia , Isoenzimas/metabolismo , Isoenzimas/fisiologia , Camundongos , Membrana Nuclear/efeitos dos fármacos , Membrana Nuclear/ultraestrutura , Proteína Quinase C/imunologia , Proteína Quinase C/fisiologia , Acetato de Tetradecanoilforbol/farmacologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA