Detalhe da pesquisa
1.
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
Biotechnol Bioeng
; 121(4): 1284-1297, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240126
2.
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
Biotechnol Bioeng
; 121(1): 291-305, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877536
3.
Combined Effects of Pressure and Ionic Strength on Protein-Protein Interactions: An Empirical Approach.
Biomacromolecules
; 25(1): 338-348, 2024 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117685
4.
Unpacking the multimodal, multi-scale data of the fast and slow lanes of the cardiac vagus through computational modelling.
Exp Physiol
; 2023 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120805
5.
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing.
Biotechnol Bioeng
; 120(4): 1068-1080, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585356
6.
Estimating and leveraging protein diffusion on ion-exchange resin surfaces.
Proc Natl Acad Sci U S A
; 117(13): 7004-7010, 2020 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179691
7.
Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents.
Biotechnol Bioeng
; 119(7): 1873-1889, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377460
8.
Displacement to separate host-cell proteins and aggregates in cation-exchange chromatography of monoclonal antibodies.
Biotechnol Bioeng
; 118(1): 164-174, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32910459
9.
In Situ Characterization of the Microstructural Evolution of Biopharmaceutical Solid-State Formulations with Implications for Protein Stability.
Mol Pharm
; 16(1): 173-183, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484319
10.
DNA RETENTION ON DEPTH FILTERS.
J Memb Sci
; 570-571: 464-471, 2019 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31223185
11.
Contributions of depth filter components to protein adsorption in bioprocessing.
Biotechnol Bioeng
; 115(8): 1938-1948, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29663326
12.
Mechanisms of precipitate formation during the purification of an Fc-fusion protein.
Biotechnol Bioeng
; 115(10): 2489-2503, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29896879
13.
Effects of Resin Architecture and Protein Size on Nanoscale Protein Distribution in Ion-Exchange Media.
Langmuir
; 34(2): 673-684, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29286243
14.
Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations.
Biotechnol Bioeng
; 114(5): 1006-1015, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27943242
15.
Characterization of Protein-Excipient Microheterogeneity in Biopharmaceutical Solid-State Formulations by Confocal Fluorescence Microscopy.
Mol Pharm
; 14(2): 546-553, 2017 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094996
16.
Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification.
Biotechnol Bioeng
; 113(6): 1260-72, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26550778
17.
Local Crystalline Structure in an Amorphous Protein Dense Phase.
Biophys J
; 109(8): 1716-23, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26488663
18.
Expression of difficult-to-remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing.
Biotechnol Bioeng
; 112(6): 1232-42, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25502542
19.
Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing.
Biotechnol Bioeng
; 111(5): 904-12, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24254318
20.
Application of mechanistic modelling in membrane and fiber chromatography for purification of biotherapeutics - A review.
J Chromatogr A
; 1716: 464588, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38217959