Assuntos
Terapia de Imunossupressão/métodos , Síndrome de Susac/complicações , Síndrome de Susac/imunologia , Adulto , Ciclofosfamida/uso terapêutico , Feminino , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Estudos Longitudinais , Imageamento por Ressonância Magnética , Metilprednisolona/uso terapêutico , Síndrome de Susac/diagnóstico por imagemRESUMO
Nephrogenic adenoma is a rare lesion of urothelial mucous membrane. At present, the cases described in literature are 85. In this work the Authors study the morphologic aspects and etiopathogenetic theories.
Assuntos
Adenoma/patologia , Neoplasias Urológicas/patologia , HumanosRESUMO
The urological complications after a renal transplantation still represent an event anything but rare, ranging, according to the different statistics, from 0.9% up to 23%, with a mortality between 0 and 25%. In this work done by the Verona Centre the experience on 274 transplantations is reported. The urological complications weighed with 6.2% and absence of mortality among the patients. The importance of the prevention and precocious diagnosis is confirmed.
Assuntos
Transplante de Rim , Obstrução Ureteral/etiologia , Fístula Urinária/etiologia , Adolescente , Adulto , Criança , Feminino , Humanos , Terapia de Imunossupressão/efeitos adversos , Masculino , Pessoa de Meia-Idade , Necrose , Complicações Pós-Operatórias , Ureter/irrigação sanguínea , Ureter/patologia , Doenças Ureterais/etiologia , Doenças da Bexiga Urinária/etiologiaAssuntos
Hiperparatireoidismo Secundário/terapia , Glândulas Paratireoides/cirurgia , Diálise Renal/efeitos adversos , Adulto , Idoso , Fosfatase Alcalina/metabolismo , Cálcio/uso terapêutico , Feminino , Humanos , Hipocalcemia/terapia , Falência Renal Crônica/complicações , Masculino , Pessoa de Meia-Idade , Glândulas Paratireoides/transplante , Hormônio Paratireóideo/sangueRESUMO
Tissue polypeptide antigen (TPA) both in normal and neoplastic urinary bladders has been studied by immunocytochemistry. A comparison of TPA with epithelial membrane antigen (EMA), keratins and carcinoembryonic antigen (CEA) in various tumor grades and stages has been performed better to define TPA role in bladder carcinomas. Well-differentiated tumors were strongly stained for TPA with a uniform staining intensity. Undifferentiated tumors were weakly stained for TPA with an uneven staining intensity. There was no relation between TPA findings and stages of invasion. However, TPA seems to be a very helpful diagnostic tool for tumor grading and staging.
Assuntos
Antígenos de Neoplasias/análise , Carcinoma de Células de Transição/imunologia , Peptídeos/análise , Neoplasias da Bexiga Urinária/imunologia , Bexiga Urinária/imunologia , Adulto , Idoso , Biópsia , Carcinoma de Células de Transição/diagnóstico , Epitélio/análise , Humanos , Queratinas/análise , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Prognóstico , Coloração e Rotulagem , Antígeno Polipeptídico Tecidual , Neoplasias da Bexiga Urinária/diagnóstico , Neoplasias da Bexiga Urinária/patologiaRESUMO
Tissue polypeptide antigen (TPA) has been detected by immunocytochemical assay on urine cytological samples from 28 asymptomatic patients, who previously had a histological diagnosis of papillary transitional cell carcinoma (PTCT) of the urinary bladder (UB), in order to evaluate its role in follow-up controls. TPA staining intensity (SI) in urothelial cells was evaluated to improve the diagnostic accuracy of cytology. Differentiated tumor cells were strongly stained for TPA, heavier than normal urothelial cells. Undifferentiated neoplastic cells were less stained for TPA with a wide range of SI. TPA detection revealed positive cytology in 21 (75%) of the considered cases. The accuracy of our cytological findings compared with both routine examinations and subsequent histopathological diagnosis was of 95.2%. Follow-up urinary cytology limits could be reduced by TPA searching in differentiated tumor cells, deriving from low-grade neoplasms.