RESUMO
We report the first case and clinical course of a case of human subcutaneous phaeohyphomycosis caused by Ochroconis tshawytschae, a rare fish pathogen. The diagnosis was based upon histopathological and mycological examinations of clinical samples. Identification of the etiologic agent was assessed on its phenotypic characteristics and subsequently, confirmed by molecular data. In vitro antifungal susceptibility of the isolate was investigated and a comparison was prepared of all of its features to those of its two most relevant related species, O. gallopava and O. humicola.
Assuntos
Ascomicetos/isolamento & purificação , Feoifomicose/microbiologia , Adulto , Antifúngicos/uso terapêutico , Ascomicetos/efeitos dos fármacos , Ascomicetos/genética , Ascomicetos/patogenicidade , DNA Espaçador Ribossômico/genética , Genes de RNAr , Humanos , Imunocompetência , Itraconazol/uso terapêutico , Masculino , Testes de Sensibilidade Microbiana , Técnicas de Tipagem Micológica/métodos , Feoifomicose/diagnóstico , Adulto JovemRESUMO
We report a case of subcutaneous phaeohyphomycosis caused by Corynespora cassiicola. Molecular identification of this pathogen on grasses confirms that it may be involved in human infection, as previously reported once in pre-molecular literature. In vitro antifungal susceptibility data of the strain are provided. The patient was successfully treated with oral terbinafine with topical povidone iodine in accordance with the results obtained through in vitro susceptibility testing.