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1.
Arthroscopy ; 40(2): 384-396.e1, 2024 02.
Artigo em Inglês | MEDLINE | ID: mdl-37270112

RESUMO

PURPOSE: To determine whether the addition of lateral extra-articular tenodesis (LET) to anterior cruciate ligament reconstruction (ACLR) would improve return-to-sport (RTS) rates in young, active patients who play high-risk sports. METHODS: This multicenter randomized controlled trial compared standard hamstring tendon ACLR with combined ACLR and LET using a strip of the iliotibial band (modified Lemaire technique). Patients aged 25 years or younger with an anterior cruciate ligament-deficient knee were included. Patients also had to meet 2 of the following criteria: (1) pivot-shift grade 2 or greater, (2) participation in a high-risk or pivoting sport, and (3) generalized ligamentous laxity. Time to return and level of RTS were determined via administration of a questionnaire at 24 months postoperatively. RESULTS: We randomized 618 patients in this study, 553 of whom played high-risk sports preoperatively. The proportion of patients who did not RTS was similar between the ACLR (11%) and ACLR-LET (14%) groups; however, the graft rupture rate was significantly different (11.2% in ACLR group vs 4.1% in ACLR-LET group, P = .004). The most cited reason for no RTS was lack of confidence and/or fear of reinjury. A stable knee was associated with nearly 2 times greater odds of returning to a high-level high-risk sport postoperatively (odds ratio, 1.92; 95% confidence interval, 1.11-3.35; P = .02). There were no significant differences in patient-reported functional outcomes or hop test results between groups (P > .05). Patients who returned to high-risk sports had better hamstring symmetry than those who did not RTS (P = .001). CONCLUSIONS: At 24 months postoperatively, patients who underwent ACLR plus LET had a similar RTS rate to those who underwent ACLR alone. Although the subgroup analysis did not show a statistically significant increase in RTS with the addition of LET, on returning, the addition of LET kept subjects playing longer by reducing graft failure rates. LEVEL OF EVIDENCE: Level I, randomized controlled trial.


Assuntos
Lesões do Ligamento Cruzado Anterior , Reconstrução do Ligamento Cruzado Anterior , Tenodese , Humanos , Tenodese/métodos , Volta ao Esporte , Ligamento Cruzado Anterior/cirurgia , Articulação do Joelho/cirurgia , Reconstrução do Ligamento Cruzado Anterior/métodos
2.
J Shoulder Elbow Surg ; 33(3): 628-639, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37981002

RESUMO

BACKGROUND: The addition of epinephrine in irrigation fluid and the intravenous or local administration of tranexamic acid have independently been reported to decrease bleeding, thereby improving surgeons' visualization during arthroscopic shoulder procedures. No study has compared the effect of intravenous tranexamic acid, epinephrine in the irrigation fluid, or the combination of both tranexamic acid and epinephrine on visual clarity during shoulder arthroscopy with a placebo group. We hypothesized that intravenous tranexamic acid is more effective than epinephrine mixed in the irrigation fluid in improving visualization during shoulder arthroscopy, with no additive effect when both are used. METHODS: Patients aged ≥18 years undergoing shoulder arthroscopy were randomized into one of 4 study arms: (1) saline irrigation fluid (placebo); (2) epinephrine (0.33 mL of 1:1000 per liter) mixed in irrigation fluid (EPI); (3) 1 g intravenous tranexamic acid (TXA); and (4) epinephrine and tranexamic acid combined (TXA + EPI). Visualization was rated intraoperatively on a scale from 0, indicating poor clarity, to 3, indicating excellent clarity, every 15 minutes and overall. The primary outcome measure was the overall rating of visualization. A stepwise linear regression was performed using visualization as the dependent variable and independent variables including presence or absence of epinephrine and tranexamic acid, surgery duration, complexity, mean arterial pressure, increase in pump pressure, and volume of irrigation fluid. RESULTS: One hundred twenty-eight patients (mean age 56 years) were randomized. Mean visual clarity for the placebo, TXA, EPI, and TXA + EPI groups were 2.0 (±0.6), 2.0 (±0.6), 2.6 (±0.5), and 2.7 (±0.5), respectively (P < .001). The presence or absence of epinephrine was the most significant predictor of visual clarity (P < .001). Tranexamic acid presence or absence had no effect. No adverse events were recorded in any of the groups. CONCLUSION: Intravenous tranexamic acid is not an effective alternative to epinephrine in irrigation fluid to improve visualization during routine arthroscopic shoulder surgeries, and there is no additive effect when both are used.


Assuntos
Antifibrinolíticos , Articulação do Ombro , Ácido Tranexâmico , Humanos , Adolescente , Adulto , Pessoa de Meia-Idade , Ombro/cirurgia , Ácido Tranexâmico/uso terapêutico , Artroscopia/métodos , Epinefrina , Articulação do Ombro/cirurgia , Antifibrinolíticos/uso terapêutico , Perda Sanguínea Cirúrgica/prevenção & controle , Método Duplo-Cego
3.
J Shoulder Elbow Surg ; 32(1): 213-222, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36067940

RESUMO

BACKGROUND: Cutibacterium acnes (C acnes) colonization can have a significant impact on patients undergoing both arthroscopic and open shoulder surgery with regard to postoperative infection. Its resistance to standard preoperative skin preparations and prophylactic antibiotics has led to a need for a more targeted therapy. Topical benzoyl peroxide (BPO) has been used by dermatologists in the treatment for acnes due to its bactericidal and penetrative effects through the dermal layer. The aim of this systematic review is to review the effectiveness of topical BPO preoperatively in shoulder surgery in reducing C acnes colonization and postoperative infection. METHODS: A review of the online databases Medline and Embase was conducted on December 15, 2021, according to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The review was registered prospectively in the PROSPERO database. Clinical studies reporting superficial and deep sample microbiology and postoperative complications were included. The studies were appraised using the revised Cochrane Risk of Bias 2 (ROB 2) tool for randomized studies and the Methodological Index for Non-Randomized Studies (MINORS) tool. RESULTS: The search strategy identified 10 studies for inclusion (6 randomized control trials, 2 prospective cohort studies, and 2 case series), including a total of 482 patients. Seven studies were comparable, testing BPO against alternative standard skin preparations. Of the 10 studies, 7 showed a decrease in the load of C acnes on the skin and/or deep tissues, of which 6 demonstrated statistical significance. Men were shown to have a statistically significant increase in the colonization rate of C acnes. Scheer et al (2021) demonstrated 4500 colony-forming units/mL in males and 900 colony-forming units/mL in females. In studies where the number of BPO applications was higher, BPO appeared more effective. Dizay et al demonstrated C acnes elimination in 78.9% with more than 1 application compared with 66.7% if only applied once. Three studies looked at the effectiveness of BPO during the operative timeline with 1 demonstrating its statistically significant effectiveness at reducing colonization 2 hours into the operation (P = .048). CONCLUSION: BPO is effective as a topical treatment at reducing C acnes colonization before shoulder surgery. However, the relationship between duration of treatment, frequency of application, and gender requires further research.


Assuntos
Peróxido de Benzoíla , Articulação do Ombro , Masculino , Feminino , Humanos , Peróxido de Benzoíla/uso terapêutico , Ombro/microbiologia , Estudos Prospectivos , Articulação do Ombro/cirurgia , Propionibacterium acnes , Pele/microbiologia
4.
Arthroscopy ; 37(9): 2960-2972, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33887411

RESUMO

PURPOSE: The purpose of this systematic review is to characterize the complications associated with superior capsule reconstruction (SCR) for the treatment of functionally irreparable rotator cuff tears (FIRCTs). METHODS: This systematic review was completed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Two independent reviewers completed a search of PubMed, Embase, and Medline databases. Studies were deemed eligible for inclusion if they reported postoperative outcomes of arthroscopic SCR for FIRCTs and considered at least 1 postoperative complication. Statistical heterogeneity was quantified via the I2 statistic. Due to marked heterogeneity, pooled proportions were not reported. All complications and patient-reported outcomes were described qualitatively. RESULTS: Fourteen studies met the inclusion/exclusion criteria. The overall complication rate post-SCR ranged from 5.0% to 70.0% (I2 = 84.9%). Image-verified graft retear ranged from 8% to 70%, I2 = 79.4%), with higher rates reported when SCR was performed using allograft (19%-70%, I2 76.6%) compared to autograft (8%-29%, I2 = 66.1%). Reoperation (0%-36%, I2 = 73.4%), revision surgeries (0%-21%, I2 = 81.2%), medical complications (0%-5%, I2 = 0.0%), and infections (0%-5%, I2 = 0.0%) were also calculated. CONCLUSIONS: SCR carries a distinct complication profile when used for the treatment of FIRCTs. The overall rate of complications ranged from 5.0% to 70.0%. The most common complication is graft retear with higher ranges in allografts (19%-70%) compared to autografts (8%-29%). The majority of studies reported at least 1 reoperation (range, 0%-36%), most commonly for revision to reverse shoulder arthroplasty. LEVEL OF EVIDENCE: Level IV, systematic review of Level IV or better investigations.


Assuntos
Lesões do Manguito Rotador , Articulação do Ombro , Artroscopia , Humanos , Amplitude de Movimento Articular , Lesões do Manguito Rotador/cirurgia , Resultado do Tratamento
5.
Clin J Sport Med ; 31(6): e442-e446, 2021 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-33914491

RESUMO

OBJECTIVE: To determine the rate of total knee replacement (TKR) after anterior cruciate ligament reconstruction (ACL-R) compared to the general population. DESIGN: Retrospective review. SETTING: All hospitals that performed TKR and ACL-R in Manitoba between 1980 and 2015. PARTICIPANT: All patients that underwent TKR and ACL-R in Manitoba between 1980 and 2015. INTERVENTION: Patient factors gathered at time of surgery included: age, sex, urban or rural residence, neighborhood income quintile, and resource utilization band (RUB). Each person was matched with up to 5 people from the general population who had never had ACL-R and had not had a TKR at the time of the case ACL-R. MAIN OUTCOME MEASURES: The rate of TKR after ACL-R. RESULTS: Overall from 1980 to 2015, 8500 ACL-R were identified within the 16 to 60 years age group with a resultant 42 497 population matches. Sex was predominantly male. The mean age of the ACL-R group at the time of TKR was 53.7 years, whereas the mean age for the matched cohort was 58.2 years, P < 0.001. Those with ACL-R were 4.85 times more likely to go on to have TKR. Apart from age, no other risk factors examined (location, year of surgery, place of residence, income quintile, and RUB) seemed to increase risk of TKR after ACL-R. CONCLUSION: Patients who underwent ACL-R were 5 times more likely to undergo TKR.


Assuntos
Lesões do Ligamento Cruzado Anterior , Reconstrução do Ligamento Cruzado Anterior , Artroplastia do Joelho , Lesões do Ligamento Cruzado Anterior/epidemiologia , Lesões do Ligamento Cruzado Anterior/cirurgia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
6.
J Shoulder Elbow Surg ; 30(8): 1733-1740, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34022365

RESUMO

BACKGROUND: The purpose of this study was to determine the incidence of Popeye deformity following biceps tenotomy vs. tenodesis and evaluate risk factors and subjective and objective outcomes. METHODS: Data for this study were collected as part of a randomized clinical trial in which patients aged ≥18 years undergoing arthroscopic shoulder surgery for a long head of the biceps tendon lesion were allocated to undergo tenotomy or tenodesis. The primary outcome measure for this secondary analysis was rate of Popeye deformity at 24 months postoperation as determined by an evaluator blinded to group allocation. Those with a deformity indicated their satisfaction with the appearance of their arm on a 10-cm visual analog scale, rated their pain and cramping, and completed the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form and the Western Ontario Rotator Cuff index. Isometric elbow flexion and supination strength were also measured. Cohen kappa was calculated to measure inter-rater reliability between patient and evaluator on the presence of a deformity. Logistic regression was performed to identify predictors of presence or absence of a Popeye deformity. RESULTS: One hundred fourteen patients were randomly assigned to 2 groups, of which 42 to the tenodesis group and 45 to the tenotomy group completed a 24-month follow-up. Based on clinical observation, the odds of a Popeye in the tenotomy group were 4.3 times greater than in the tenodesis group (P = .018) with incidence of 33% (15/45) and 9.5% (4/42), respectively. Surgical technique was the only significant predictor of perceived deformity, with male gender trending toward significance (odds ratio 7.33, 95% confidence interval 0.867-61.906, P = .067). Mean (standard deviation) satisfaction score of those with a deformity regarding appearance of their arm was 7.3 (2.6). Increasing satisfaction was correlated with increasing age (r = 0.640, P = .025), but there was no association with gender (r = -0.155, P = .527) or body mass index (r = -0.221, P = .057). Differences in subjective outcomes were dependent on whether the Popeye was clinician- or self-assessed. CONCLUSION: The odds of developing a perceived Popeye deformity was 4.3 higher after tenotomy compared to tenodesis based on clinician observation. Male gender was trending toward being predictive of having a deformity. Pain and cramping were increased in those with a self-reported Popeye. Younger patients were significantly less satisfied with a deformity despite no difference in functional outcomes at 24 months. Thus, biceps tenodesis may be favored in younger male patients to minimize the risk of Popeye and the risk of dissatisfaction in the appearance of their arm following surgery.


Assuntos
Lesões do Manguito Rotador , Tenodese , Adolescente , Adulto , Braço , Artroscopia , Índice de Massa Corporal , Humanos , Incidência , Masculino , Ontário , Satisfação Pessoal , Estudos Prospectivos , Reprodutibilidade dos Testes , Lesões do Manguito Rotador/cirurgia , Tenotomia
7.
Clin J Sport Med ; 30(6): e207-e213, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-30312185

RESUMO

OBJECTIVE: To determine epidemiological trends of anterior cruciate ligament reconstruction (ACL-R) in a Canadian province, estimate the national incidence, and compare with internationally published data. DESIGN: Retrospective review. SETTING: All hospitals that performed ACL reconstructions in Manitoba between 1980 and 2015. PARTICIPANT: All patients that underwent ACL-R in Manitoba between 1980 and 2015. INTERVENTION: This is a retrospective review looking at deidentified, individual-level administrative records of health services used for the entire population of Manitoba (approximately 1.3 million). Codes for ACL and cruciate ligament reconstruction were searched from 1980 to 2015. Patient demographics included age, sex, geographic area of residence, and neighborhood income quintile. MAIN OUTCOME MEASURES: Trends of ACL reconstructions from 1980 to 2015. RESULTS: A total of 10 114 ACL-R were performed during the 36-year study period and patients were predominantly male (63.1%). The mean age at ACL-R was 29.5 years (SD 10.0) for males and 28.5 years (SD 11.9) for females, whereas age younger than 40 years accounted for 81.7% of all ACL-R. The incidence of ACL-R increased from 7.56/100 000 inhabitants in 1980 to 48.45/100 000 in 2015. The proportion of females undergoing ACL-R has increased from 29.3% in 1980% to 41.9% in 2015, and female patients now comprise the majority of ACL-R in the under-20 age category. CONCLUSION: The incidence of ACL-R has significantly increased since 1980; female patients now make up a greater proportion than males of the ACL-R population younger than 20 years. This information can be used to guide resource allocation planning and focus injury prevention initiatives.


Assuntos
Reconstrução do Ligamento Cruzado Anterior/tendências , Adulto , Reconstrução do Ligamento Cruzado Anterior/estatística & dados numéricos , Feminino , Humanos , Masculino , Manitoba , Avaliação de Resultados em Cuidados de Saúde , Estudos Retrospectivos , Distribuição por Sexo , Fatores de Tempo , Adulto Jovem
8.
Instr Course Lect ; 68: 513-544, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-32032066

RESUMO

The management of knee ligament injuries continues to evolve, and much debate persists over the timing of surgery, repair versus reconstruction, surgical technique, postoperative rehabilitation, graft selection, and fixation. Surgeons should be aware of updates on the best management strategies of knee ligament injuries in 2018 and understand the important history and physical examination findings of the knee with ligamentous injury; the anterior cruciate ligament; the role of the anterolateral ligament and lateral extra-articular tenodesis; combined anterior cruciate ligament and medial collateral ligament injuries; the posterior cruciate ligament; medial collateral ligament repair versus reconstruction; posterolateral corner repair versus reconstruction; the role of coronal plane osteotomies, including high tibial osteotomy and distal femoral osteotomy; the role of sagittal plane osteotomies, including anterior closing wedge osteotomy and anterior opening wedge osteotomy; the initial management of the multiligament-injured knee; and five keys to avoiding complications in the multiligament-injured knee. The best available evidence and sample case presentations help guide surgical decision making and improve patient outcomes.


Assuntos
Lesões do Ligamento Cruzado Anterior , Instabilidade Articular , Traumatismos do Joelho , Ligamento Cruzado Posterior , Ligamento Cruzado Anterior , Humanos , Articulação do Joelho , Tíbia
11.
J Strength Cond Res ; 33(11): 2909-2912, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31644516

RESUMO

Cordingley, DM, Sirant, L, MacDonald, PB, and Leiter, JR. Three-year longitudinal fitness tracking in top-level competitive youth ice hockey players. J Strength Cond Res 33(11): 2909-2912, 2019-The purpose of this retrospective review was to report the physical and physiological development of top-level competitive male youth hockey players for 3 consecutive years (13, 14, and 15 years of age). Before each hockey season, the athletes (n = 103) underwent a fitness testing combine to assess aerobic, anaerobic, and musculoskeletal fitness. The tests performed included the height, body mass, body fat percentage determined by skinfolds, push-ups, chin-ups, plank, broad jump, grip strength 20-m shuttle run, Wingate bike test, and 5-10-5 shuttle test. Height and body mass increased with each consecutive year (p < 0.05) with no change in body fat percentage. Chin-ups, broad jump, and grip strength all improved with age (p < 0.001). However, push-ups only improved from 13 to 14 years of age (p < 0.001), whereas maximal plank duration decreased from 14 to 15 years of age (p < 0.05). The total distance covered during the 20-m shuttle run decreased from 14 to 15 years of age (p < 0.05). Absolute peak and average power increased with each age increase (p < 0.001), but relative peak and average power only increased from 13 to 14 years of age (p < 0.05). There was no change in the fatigue index with age. The 5-10-5 shuttle test improved with each age increase (p < 0.05). Over a 3-year period (13-15 years of age), there are many physical and physiological changes that occur in top-level competitive male hockey players. Having a better understanding of how these athletes develop could aid in the implementation of specific on- and off-ice training programs.


Assuntos
Desenvolvimento do Adolescente , Atletas , Hóquei/fisiologia , Aptidão Física , Adolescente , Antropometria , Teste de Esforço , Humanos , Estudos Longitudinais , Masculino , Músculo Esquelético/fisiologia , Estudos Retrospectivos , Esportes Juvenis
12.
Can J Surg ; 61(5): 345-349, 2018 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-30247012

RESUMO

Background: Postgraduate medical residency programs are laborious and timeintensive, and can be physically, intellectually and emotionally demanding. These working conditions may lead to the neglect of personal health and well-being. The objective of this study was to compare the anthropometric and fitness characteristics of surgical and nonsurgical medical residents. We hypothesized that there is a difference in physical health between these 2 groups. Methods: Medical residents completed a demographic information questionnaire and were assessed by trained staff for height, weight, body fat percentage, muscular strength and endurance, and peak oxygen consumption (V̇ᴏ2peak). The average number of working hours per week was also documented. Results: Forty-five residents (21 surgical and 24 nonsurgical; 31 men and 14 women) participated in the study. Surgical residents worked more hours per week on average than nonsurgical residents (p = 0.02) and had a higher body mass index (BMI) (p = 0.04) and lower V̇ᴏ2peak (p = 0.01). Conclusion: Surgical residents worked more hours than nonsurgical residents, which may have contributed to their higher BMI and lower aerobic fitness levels. Despite a heavy workload, it is important for all medical residents to find strategies to promote a healthy lifestyle for both themselves and their patients to ensure long-term well-being.


Contexte: En médecine, les programmes de résidence postdoctoraux sont fastidieux et chronovores; et ils peuvent être exigeants physiquement, intellectuellement et émotivement. De telles conditions de travail forcent parfois les résidents à négliger leur santé et leur bien-être personnels. L'objectif de cette étude était de comparer les caractéristiques anthropométriques et la forme physique des résidents de chirurgie et d'autres spécialités médicales. Selon notre hypothèse, ces 2 groupes ne présentent pas le même état de santé physique. Méthodes: Les résidents ont répondu à un questionnaire démographique et des assistants dument formés ont mesuré leur taille, leur poids, leur pourcentage de graisse corporelle, leur force musculaire, leur endurance et leur consommation d'oxygène maximale (V̇ᴏ2max). Le nombre d'heures de travail hebdomadaires a aussi été pris en compte. Résultats: Quarante-cinq résidents (21 de chirurgie et 24 d'autres spécialités; 31 hommes et 14 femmes) ont participé à l'étude. Les résidents en chirurgie travaillaient en moyenne plus d'heures par semaine que les autres résidents (p = 0,02) et présentaient un indice de masse corporelle (IMC) plus élevé (p = 0,04) et une V̇ᴏ2max plus basse (p = 0,01). Conclusion: résidents en chirurgie travaillaient plus d'heures que les autres résidents, ce qui peut avoir contribué à leur IMC plus élevé et à leur moins bonne capacité aérobique. Malgré la lourdeur de leur fardeau de travail, il est important que tous les résidents en médecine trouvent des stratégies pour adopter de saines habitudes de vie pour eux-mêmes et leurs patients, et assurer leur mieux-être à long terme.


Assuntos
Índice de Massa Corporal , Nível de Saúde , Internato e Residência/estatística & dados numéricos , Aptidão Física/fisiologia , Médicos/estatística & dados numéricos , Cirurgiões/estatística & dados numéricos , Carga de Trabalho/estatística & dados numéricos , Adulto , Feminino , Humanos , Masculino , Manitoba
13.
J Strength Cond Res ; 32(9): 2612-2615, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29239995

RESUMO

Leiter, JR, Cordingley, DM, and MacDonald, PB. Development of anaerobic fitness in top-level competitive youth ice hockey players. J Strength Cond Res 32(9): 2612-2615, 2018-Ice hockey is a physiologically complex sport involving both the anaerobic and aerobic energy systems. The purpose of this study was to evaluate the anaerobic power output (PO) of top-level competitive youth hockey players. It was hypothesized that with each successive increase in age, there would be an associated change in anaerobic PO. Two hundred and fifty-one male hockey players between the ages of 13-17 years participated in this study. All athletes completed a 30-second Wingate test as part of a preseason physiological and fitness combine. A 1-way analysis of variance was performed to compare peak PO (POpeak), average PO (POavg), and fatigue index between all age groups. A Tukey's post hoc test was used to determine changes in immediately successive age groups for all variables. Age categories were grouped as 13 years old (yrs) (n = 72), 14 yrs (n = 68), 15 yrs (57) and 16 yrs (n = 54, including 11 athletes 17 yrs). Absolute POpeak significantly increased with all age increases. Relative POpeak, absolute POavg, and relative POavg increased between the ages of 13 and 14 years, and 14 and 15 years, but not between the ages 15 and 16 years. There were no changes in fatigue index between any successive age groups. Anaerobic PO increases with an increase in age with no associated change in fatigue index. Athletes, coaches, and parents can use this normative data to help prepare the player for upcoming seasons in which there may be an increase in level or age class.


Assuntos
Limiar Anaeróbio/fisiologia , Hóquei/fisiologia , Aptidão Física/fisiologia , Adolescente , Fatores Etários , Estudos Transversais , Teste de Esforço , Humanos , Masculino , Estudos Retrospectivos
14.
Muscle Nerve ; 55(5): 715-726, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-27571286

RESUMO

INTRODUCTION: Rotator-cuff injury (RCI) represents 50% of shoulder injuries, and prevalence increases with age. Even with successful tendon repair, muscle and joint function may not return. METHODS: To explore the dysfunction, supraspinatus and ipsilateral deltoid (control) muscles were biopsied during arthroscopic RCI repair for pair-wise histological and protein-expression studies. RESULTS: Supraspinatus showed fiber atrophy (P < 0.0001), fibrosis (by Sirius Red, P = 0.05), reduced vascular density (P < 0.001), and a lower proportion of slow fibers (P < 0.0001) compared with the ipsilateral control muscle. There were also higher levels of atrogin-1 (P = 0.05), vascular endothelial growth factor (VEGF, P < 0.01), and dystrophin (P < 0.008, relative to fiber diameter) versus control. CONCLUSIONS: Adaptive changes in vascular endothelial growth factor and dystrophin were likely associated with reduced vascular supply, fatigue resistance, and fibrosis, accompanied by disuse atrophy from mechanical unloading of supraspinatus after tendon tear. Treatment to promote growth and vascularity in atrophic supraspinatus muscle may help improve functional outcome after surgical repair. Muscle Nerve 55: 715-726, 2017.


Assuntos
Fibras Musculares de Contração Rápida/patologia , Atrofia Muscular/patologia , Lesões do Manguito Rotador/patologia , Idoso , Miosinas Cardíacas/metabolismo , Distrofina/metabolismo , Feminino , Fibrose/diagnóstico por imagem , Fibrose/metabolismo , Fibrose/patologia , Fibrose/fisiopatologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Metaloproteinase 9 da Matriz/metabolismo , Pessoa de Meia-Idade , Fibras Musculares de Contração Rápida/metabolismo , Proteínas Musculares/metabolismo , Atrofia Muscular/diagnóstico por imagem , Atrofia Muscular/metabolismo , Atrofia Muscular/fisiopatologia , Cadeias Pesadas de Miosina/metabolismo , Lesões do Manguito Rotador/diagnóstico por imagem , Lesões do Manguito Rotador/metabolismo , Lesões do Manguito Rotador/fisiopatologia , Proteínas Ligases SKP Culina F-Box/metabolismo , Fator A de Crescimento do Endotélio Vascular/metabolismo
15.
Can J Surg ; 60(4): 273-279, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28730988

RESUMO

BACKGROUND: This study aimed to assess differences in the fixation and functional outcomes between pegged and keeled all-polyethylene glenoid components for standard total shoulder arthroplasty. METHODS: Patients were randomized to receive a keeled or pegged all-polyethylene glenoid component. We used model-based radiostereometric analysis (RSA) to assess glenoid fixation and subjective outcome measures to assess patient function. Follow-up examinations were completed at 6 weeks and 6, 12 and 24 months after surgery. Modifications to the RSA surgical, imaging and analytical techniques were required throughout the study to improve the viability of the data. RESULTS: Stymied enrolment resulted in only 16 patients being included in our analyses. The RSA data indicated statistically greater coronal plane migration in the keeled glenoid group than in the pegged group at 12 and 24 months. Functional outcome scores did not differ significantly between the groups at any follow-up. One patient with a keeled glenoid showed high component migration after 24 months and subsequently required revision surgery 7 years postoperatively. CONCLUSION: Despite a small sample size, we found significant differences in migration between glenoid device designs. Although clinically these findings are not robust, we have shown the feasibility of RSA in total shoulder arthroplasty as well as the value of a high-precision metric to achieve objective results in a small group of patients.


CONTEXTE: Cette étude avait pour objet d'évaluer les différences sur le plan de la fixation et des résultats fonctionnels entre les composants glénoïdiens à plots et à quille, tous deux en polyéthylène, dans une arthroplastie totale traditionnelle de l'épaule. MÉTHODES: La répartition des composants glénoïdiens en polyéthylène à plots et à quille a été faite de façon aléatoire. Nous nous sommes servis de modèles d'analyses radiostéréométriques (ARS) pour évaluer la fixation glénoïdienne et les indicateurs de résultats subjectifs, ce qui nous a ainsi permis d'évaluer les résultats fonctionnels des patients. Quatre examens de suivi ont été réalisés après la chirurgie : à 6 semaines, puis à 6 mois, à 12 mois et à 24 mois. Tout au long de l'étude, des ajustements ont été apportés aux modèles d'ARS de la chirurgie, de l'imagerie et des analyses afin d'améliorer la viabilité des données. RÉSULTATS: Des problèmes liés au recrutement ont fait en sorte que nous n'avons retenu que 16 patients dans le cadre de nos analyses. Les données d'ARS ont montré une migration statistiquement plus grande du plan frontal dans le groupe quille que dans le groupe plots à 12 et à 24 mois. Les résultats fonctionnels étaient sensiblement les mêmes d'un groupe à l'autre, peu importe le moment du suivi. Un patient du groupe quille a présenté une migration très importante du composant après 24 mois; il a dû subir une chirurgie de révision 7 ans après la chirurgie initiale. CONCLUSION: Malgré la petite taille de l'échantillon, nous avons observé des différences significatives dans la migration des composants, selon le type utilisé. Même si ces observations ne permettent pas d'arriver à des conclusions robustes d'un point de vue clinique, nous avons montré qu'il est possible d'avoir recours aux ARS en contexte d'arthroplastie totale de l'épaule et démontré la valeur associée à l'utilisation de mesures de haute précision pour l'obtention de résultats objectifs chez un petit groupe de patients.


Assuntos
Artroplastia do Ombro/métodos , Cavidade Glenoide , Avaliação de Processos e Resultados em Cuidados de Saúde , Polietileno , Desenho de Prótese/normas , Falha de Prótese , Análise Radioestereométrica/métodos , Reoperação , Prótese de Ombro/normas , Artroplastia do Ombro/efeitos adversos , Estudos de Viabilidade , Seguimentos , Humanos , Desenho de Prótese/efeitos adversos
16.
Am J Physiol Cell Physiol ; 309(6): C383-91, 2015 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-26135801

RESUMO

The high frequency of poor outcome and chronic pain after surgical repair of shoulder rotator-cuff injury (RCI) prompted this study to explore the potential to amplify muscle regeneration using nitric oxide (NO)-based treatment. After preoperative magnetic resonance imaging (MRI), biopsies of supraspinatus and ipsilateral deltoid (as a control) were collected during reparative surgery for RCI. Muscle fiber diameter, the pattern of neuromuscular junctions observed with alpha-bungarotoxin staining, and the γ:ε subunit ratio of acetylcholine receptors in Western blots were examined in tandem with experiments to determine the in vitro responsiveness of muscle satellite cells to activation (indicated by uptake of bromodeoxyuridine, BrdU) by the NO-donor drug, isosorbide dinitrate (ISDN). Consistent with MRI findings of supraspinatus atrophy (reduced occupation ratio and tangent sign), fiber diameter was lower in supraspinatus than in deltoid. ISDN induced a significant increase over baseline (up to 1.8-fold), in the proportion of BrdU+ (activated) Pax7+ satellite cells in supraspinatus, but not in deltoid, after 40 h in culture. The novel application of denervation indices revealed a trend for supraspinatus muscle to have a higher γ:ε subunit ratio than deltoid (P = 0.13); this ratio inversely with both occupancy ratio (P < 0.05) and the proportion of clusters at neuromuscular junctions (P = 0.05). Results implicate possible supraspinatus denervation in RCI and suggest NO-donor treatment has potential to promote growth in atrophic supraspinatus muscle after RCI and improve functional outcome.


Assuntos
Músculo Deltoide/inervação , Músculo Deltoide/patologia , Fibras Musculares Esqueléticas/patologia , Atrofia Muscular/patologia , Manguito Rotador/inervação , Manguito Rotador/patologia , Células Satélites de Músculo Esquelético/patologia , Idoso , Animais , Músculo Deltoide/metabolismo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Denervação Muscular , Fibras Musculares Esqueléticas/metabolismo , Junção Neuromuscular/metabolismo , Junção Neuromuscular/patologia , Óxido Nítrico/metabolismo , Regeneração/fisiologia , Células Satélites de Músculo Esquelético/metabolismo , Ombro/inervação , Ombro/patologia
17.
Instr Course Lect ; 64: 521-30, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25745935

RESUMO

Multiligament knee injuries are relatively rare, but the outcomes can be disastrous if they are not identified and treated appropriately. Recent trends in the literature are showing more focus on early identification and subspecialist management as important ways to achieve the best possible outcomes for these injuries. Early identification and the appropriate treatment of associated injury patterns are the keys to improving outcomes. These injuries are usually associated with high-energy trauma, but low-energy injuries also cause these severe injuries in patients with other comorbidities, such as those with high body mass indices. Familiarity with an evidence-based approach is helpful for managing these complex injuries.


Assuntos
Traumatismos em Atletas/cirurgia , Luxação do Joelho/cirurgia , Traumatismos do Joelho/cirurgia , Ligamentos Articulares/cirurgia , Procedimentos Ortopédicos/métodos , Procedimentos de Cirurgia Plástica/métodos , Humanos , Ligamentos Articulares/lesões
18.
J Strength Cond Res ; 29(11): 3223-8, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26506063

RESUMO

Ice hockey is a physiologically complex sport requiring aerobic and anaerobic energy metabolism. College and professional teams often test aerobic fitness; however, there is a paucity of information regarding aerobic fitness of elite youth players. Without this knowledge, training of youth athletes to meet the standards of older age groups and higher levels of hockey may be random, inefficient, and or effective. Therefore, the purpose of this study was to determine the aerobic fitness of elite youth hockey players. A retrospective database review was performed for 200 male AAA hockey players between the ages of 13 and 17 (age, 14.4 ± 1.2 years; height, 174.3 ± 8.5 cm; body mass, 67.2 ± 11.5 kg; body fat, 9.8 ± 3.5%) before the 2012-13 season. All subjects performed a graded exercise test on a cycle ergometer, whereas expired air was collected by either a Parvo Medics TrueOne 2400 or a CareFusion Oxycon Mobile metabolic cart to determine maximal oxygen consumption (V[Combining Dot Above]O2max). Body mass, absolute V[Combining Dot Above]O2max, and the power output achieved during the last completed stage increased in successive age groups from age 13 to 15 years (p ≤ 0.05). Ventilatory threshold (VT) expressed as a percentage of V[Combining Dot Above]O2max and the heart rate (HR) at which VT occurred decreased between the ages of 13 and 14 years (p ≤ 0.05), whereas the V[Combining Dot Above]O2 at which VT occurred increased from the age of 14-15 years. There were no changes in relative V[Combining Dot Above]O2max or HRmax between any successive age groups. The aerobic fitness levels of elite youth ice hockey players increased as players age and mature physically and physiologically. However, aerobic fitness increased to a lesser extent at older ages. This information has the potential to influence off-season training and maximize the aerobic fitness of elite amateur hockey players, so that these players can meet standards set by advanced elite age groups.


Assuntos
Desenvolvimento do Adolescente/fisiologia , Hóquei/fisiologia , Aptidão Física/fisiologia , Adolescente , Teste de Esforço , Frequência Cardíaca/fisiologia , Humanos , Masculino , Consumo de Oxigênio/fisiologia , Estudos Retrospectivos
19.
Knee Surg Sports Traumatol Arthrosc ; 22(5): 1061-9, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-23595537

RESUMO

PURPOSE: To investigate the differences in the incidence and severity of knee osteoarthritis (OA), joint space narrowing, knee laxity, and knee flexion and extension strength between an anterior cruciate ligament (ACL)-reconstructed knee and the contralateral non-reconstructed limb. METHODS: Retrospective case series of patients from a single surgeon that had an ACL reconstruction with a semitendinosus/gracilis autograft more than 12 years ago. Outcome measures included radiographic analysis, International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC), KT-1000, Tegner Activity Level Scale, Lysholm Knee Score, ACL quality of life score (ACL-QOL) and knee flexor/extensor strength. RESULTS: Seventy-four patients consented and sixty-eight (43 male, 25 female) were included for analysis. Average age (SD) at the time of surgery was 31.2 (±9.1) years. At follow-up of 14.6 (1.9) years, 9% had re-ruptured their ACL, whereas 5% ruptured the contralateral ACL. Reconstructed knees had a greater incidence and severity of OA (P < 0.01). Medial meniscus surgery was a strong predictor of OA. Seventy-five per cent scored a normal or nearly normal knee on the IKDC. The mean Lysholm score was 75.8% and Tegner Activity Level Scale scores decreased (P < 0.001) from the time of surgery. Knee extension strength was greater in the contralateral knee at speeds of 60°/s (P = 0.014) and 150°/s (P = 0.012). CONCLUSIONS: Reconstructed knees have a greater incidence and severity of OA than non-reconstructed knees, which suggests degenerative changes are secondary to ACL rupture. Medial meniscus surgery is a strong predictor of OA. Despite this, 75% of patients reported good outcomes.


Assuntos
Reconstrução do Ligamento Cruzado Anterior , Ligamento Cruzado Anterior/cirurgia , Traumatismos do Joelho/cirurgia , Osteoartrite do Joelho/etiologia , Adulto , Lesões do Ligamento Cruzado Anterior , Reconstrução do Ligamento Cruzado Anterior/efeitos adversos , Autoenxertos , Feminino , Seguimentos , Humanos , Instabilidade Articular/etiologia , Traumatismos do Joelho/complicações , Articulação do Joelho/cirurgia , Masculino , Amplitude de Movimento Articular , Estudos Retrospectivos , Adulto Jovem
20.
Knee Surg Sports Traumatol Arthrosc ; 22(9): 2187-93, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24096377

RESUMO

PURPOSE: To compare the accuracy and reliability of the anatomic and radiographic techniques for identifying the isometric point of the knee. METHODS: Only four specimens were used; however, eight experienced multiligament knee injury surgeons were recruited to address this limitation. Surgeons estimated the isometric point (EIP) on the medial and lateral sides using an anatomic and radiographic method. The x and y coordinates of the EIP were compared to the true isometric point (TIP). T-tests and interclass correlation coefficients (ICC) were performed to determine the accuracy and reliability between the methods. RESULTS: There was no difference in placement of the EIP on the medial side of the knee in the anterior/posterior (x; p = n.s.) and superior/inferior direction (y; p = n.s). The EIP was anterior (p = 0.001) to the TIP with the radiographic method on the lateral side and approached significance (p = 0.05) in the superior/inferior direction. The ICC (95% CI) for identifying the EIP on the medial side in the anterior/posterior direction using the anatomic method was 0.64 (0.28-0.96) and 0.11 (-0.06 to 0.77) in the superior/inferior direction. Using the radiographic method, the ICC in the anterior/posterior and superior/inferior direction was 0.49 (0.14-0.94) and 0.15 (-0.47 to 0.81), respectively. On the lateral side, the ICC for the anatomic method was 0.84 (0.56-0.99) in the anterior/posterior direction and 0.36 (0.05-0.90) in the superior/inferior direction. Using the radiographic method, the ICC in the anterior/posterior and superior/inferior direction was 0.61 (0.26-0.96) and 0.89 (0.67-0.99), respectively. CONCLUSIONS: There was no difference in accuracy on the medial side of the knee. On the lateral side, the anatomic method was more accurate in the anterior/posterior direction. Reliability was greater in the anterior/posterior direction on both sides of the knee. Surgeons were most likely to place the isometric point anterior and superior to the TIP on both the medial and lateral sides of the knee with either method which has the potential to cause graft lengthening. This should be taken into consideration during reconstruction/repair of the MCL/PMC and LCL/PLC.


Assuntos
Fêmur/anatomia & histologia , Articulação do Joelho/anatomia & histologia , Ligamentos Articulares/anatomia & histologia , Pesos e Medidas Corporais , Cadáver , Feminino , Fêmur/diagnóstico por imagem , Humanos , Articulação do Joelho/diagnóstico por imagem , Ligamentos Articulares/diagnóstico por imagem , Masculino , Variações Dependentes do Observador , Radiografia , Reprodutibilidade dos Testes
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