[The reaction of the thyroid neural structures in guinea pigs to ionizing radiation exposure]. / Reaktsiia nervnykh struktur shchitovidnoi zhelezy morskikh svinok na vozdeistvie ioniziruiushchei radiatsii.

State and structural organization of the guinea pig thyroid gland were studied histochemically in distanced terms (6 months) after the single external x-ray radiation 12.9 C/kg in doze. with the following intraperitoneal introduction of 131 6.5 C/kg in doze. Atrophically changed zones of parenchyma were observed along with regions of extra- and intrafollicular hyperplasia with compensatory-adaptive manifestations aimed at hormonopoiesis increase. Growth of sympathetic innervation of the vessel walls and around the follicles were found in areas of high functional activity. Direct contact between adrenergic axons and thyrocytes was demonstrated by means of electron microscopy. In parenchyma areas with signs of atrophia, adrenergic nerve fibers and terminals are located only in vessels. Thus, connection between the state of the thyroid gland sympathetic innervation and structural organization of its parenchyma in distanced terms of radiational effects was followed up.

[Sympathetic innervation of various endocrine organs in chronic action of lead acetate]. / Simpaticheskaia innervatsiia nekotorykh éndokrinnykh organov pri khronicheskom deistvii atsetata svintsa.

Structure and innervation of paraventricular and supraoptic hypothalamic nuclei, thyroid gland, adrenals and ovaries were studied by methods of histochemistry and electron microscopy in guinea pigs following chronic treatment with lead acetate in doses 50.10 and 0.1 mg/kg per day. A certain dependence between sympathoadrenal system activity and morphofunctional parameters of the endocrine organs studied was established, which is determined by the pathogenic factor dose and duration of effect.

[Morphofunctional characteristics of the ovaries, thyroid gland and adrenal glands in experimental lead acetate poisoning]. / Morfofunktsional'naia kharakteristika iaichnikov, shchitovidnoi zhelezy i nadpochechnikov pri éksperimental'nom otravlenii uksusnokislym svintsom.

Daily doses of 50 mg/kg of lead acetate injected into the laboratory animals induce morphologic changes in the parenchyma of ovaries, thyroid gland, adrenals and compromises neural mediating processes in paraventricular and supraoptic nuclei of hypothalamus. The observed morphologic changes are similar to those characteristic for intensive functioning. Prolonged exposure to lead acetate (daily dose 10 mg/kg) results in adaptation and compensation, which preserves the functional potential of the organs. The morphologic changes in the endocrine organs do not lead to significant hormonal changes.