Development of Nanozymatic Characteristics in Metal-Doped Oxide Nanomaterials.

Nanozymes are nanoscale materials that exhibit enzymatic-like activity, combining the benefits of nanomaterials with biocatalytic effects. The addition of metals to nanomaterials can enhance their nanozyme activity by mimicking the active sites of enzymes, providing structural support and promoting redox activity. In this study, nanostructured oxide and silicate-phosphate nanomaterials with varying manganese and copper additions were characterized. The objective was to assess the influence of metal modifications (Mn and Cu) on the acquisition of the nanozymatic activity by selected nanomaterials. An increase in manganese content in each material enhanced proteolytic activity (from 20 to 40 mUnit/mg for BG-Mn), while higher copper addition in glassy materials increased activity by 40%. Glassy materials exhibited approximately twice the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical activity (around 40 µmol/mL) compared to that of oxide materials. The proteolytic and antioxidant activities discussed in the study can be considered indicators for evaluating the enzymatic properties of the nanomaterials. Observations conducted on nanomaterials may aid in the development of materials with enhanced catalytic efficiency and a wide range of applications.

Inorganic Nanomaterials Used in Anti-Cancer Therapies:Further Developments.

In this article, we provide an overview of the progress of scientists working to improve the quality of life of cancer patients. Among the known methods, cancer treatment methods focusing on the synergistic action of nanoparticles and nanocomposites have been proposed and described. The application of composite systems will allow precise delivery of therapeutic agents to cancer cells without systemic toxicity. The nanosystems described could be used as a high-efficiency photothermal therapy system by exploiting the properties of the individual nanoparticle components, including their magnetic, photothermal, complex, and bioactive properties. By combining the advantages of the individual components, it is possible to obtain a product that would be effective in cancer treatment. The use of nanomaterials to produce both drug carriers and those active substances with a direct anti-cancer effect has been extensively discussed. In this section, attention is paid to metallic nanoparticles, metal oxides, magnetic nanoparticles, and others. The use of complex compounds in biomedicine is also described. A group of compounds showing significant potential in anti-cancer therapies are natural compounds, which have also been discussed.