Assuntos
Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos/complicações , Doença de Chagas/complicações , Miosite/imunologia , Fibrose Retroperitoneal/imunologia , Arteríolas/patologia , Doença Crônica , Humanos , Masculino , Pessoa de Meia-Idade , Miosite/patologia , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Fibrose Retroperitoneal/diagnóstico por imagemRESUMO
Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency (PID) in general population. PID are genetic diseases that share a dysfunction in the immune system entailing a greater risk of both chronic and recurrent infections. These patients can also develop chronic gastrointestinal infections caused by norovirus with persistent viral dissemination, which can be detected months after primoinfection. Additionally, a proportion of CVID patients show a typical severe enteropathy presenting with recurrent diarrhoea, intestinal malabsorption, inflammatory lesions, and villous atrophy. Some studies have related this enteropathy with chronic intestinal infection caused by norovirus.
Assuntos
Infecções por Caliciviridae , Imunodeficiência de Variável Comum , Gastroenteropatias , Doença Enxerto-Hospedeiro , Humanos , Imunodeficiência de Variável Comum/complicações , Imunodeficiência de Variável Comum/patologia , Reinfecção , Infecções por Caliciviridae/complicações , Infecções por Caliciviridae/patologia , Diarreia , Doença Enxerto-Hospedeiro/complicaçõesRESUMO
BACKGROUND: Sarcopenia is characterized by the loss of skeletal muscle mass and strength and represents a risk factor for frailty, loss of independence and physical disabilities. This study aimed to assess the prevalence of sarcopenia in a population of patients admitted to a media and long-stay unit. PATIENTS AND METHODS: Descriptive, cross-sectional observational study that included 166 patients over 18 years who were admitted consecutively for a year to palliative care, convalescence or rehabilitation. Administrative and anthropometric data were recorded. Sarcopenia detection was performed by assessing the strength in the scapular and pelvic girdle muscles, grip strength in the hands, muscle mass and physical functional capacity. RESULTS: The overall prevalence of sarcopenia was 77.6%. Most patients had severe sarcopenia (91.2%), with reduced levels of the 3 assessed parameters: muscle strength (88.2%), muscle mass (85.5%) and physical performance (94.70%). CONCLUSION: The prevalence of sarcopenia in patients admitted to our media and long-stay unit is higher than that reported in noninstitutionalized populations, and often has a significant degree of severity.