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J Infect Dis ; 229(2): 341-345, 2024 Feb 14.
Artigo em Inglês | MEDLINE | ID: mdl-37523757

RESUMO

BACKGROUND: Patients with chronic hepatitis C virus (HCV) do not respond to hepatitis B virus (HBV) vaccination as efficiently as the general population. We assessed if revaccination after HCV treatment resulted in improved response. METHODS: Previous HBV vaccine nonresponders were prospectively recruited for revaccination after HCV eradication. Hepatitis B surface antibody (HBsAb) testing was performed 1 month after series completion. RESULTS: Follow-up HBsAb testing was performed in 31 of 34 enrolled patients with 21 (67.7%) reactive results. There were no significant differences in HBsAb reactivity based on age, sex, race, or advanced fibrosis presence. CONCLUSIONS: HBV vaccine nonresponders should be considered for revaccination following HCV cure.


Assuntos
Hepatite B , Hepatite C Crônica , Hepatite C , Humanos , Imunização Secundária , Hepatite C Crônica/tratamento farmacológico , Hepatite C Crônica/prevenção & controle , Hepatite B/prevenção & controle , Vírus da Hepatite B , Vacinas contra Hepatite B , Anticorpos Anti-Hepatite B , Antígenos de Superfície da Hepatite B
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