Pesquisa | BVS Educação Profissional em Saúde

1.

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma.

Cirrincione, Anthony M; Poos, Alexandra M; Ziccheddu, Bachisio; Kaddoura, Marcella; Baertsch, Marc-Andrea; Maclachlan, Kylee H; Chojnacka, Monika; Diamond, Benjamin T; John, Lukas; Reichert, Philipp; Huhn, Stefanie; Blaney, Patrick; Gagler, Dylan C; Rippe, Karsten; Zhang, Yanming; Dogan, Ahmet; Lesokhin, Alexander M; Davies, Faith E; Goldschmidt, Hartmut; Fenk, Roland; Weisel, Katja C; Mai, Elias K; Korde, Neha; Morgan, Gareth J; Usmani, Saad Z; Landgren, Ola; Raab, Marc S; Weinhold, Niels; Maura, Francesco.

Blood ; 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38728430

2.

A phase 2 clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma.

Giesen, Nicola; Chatterjee, Manik; Scheid, Christof; Poos, Alexandra M; Besemer, Britta; Miah, Kaya; Benner, Axel; Becker, Nicole; Moehler, Thomas; Metzler, Ivana; Khandanpour, Cyrus; Seidel-Glaetzer, Andrea; Trautmann-Grill, Karolin; Kortüm, K Martin; Müller-Tidow, Carsten; Mechtersheimer, Gunhild; Goeppert, Benjamin; Stenzinger, Albrecht; Weinhold, Niels; Goldschmidt, Hartmut; Weisel, Katja; Raab, Marc S.

Blood ; 141(14): 1685-1690, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-36608320

3.

Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis.

Poos, Alexandra M; Prokoph, Nina; Przybilla, Moritz J; Mallm, Jan-Philipp; Steiger, Simon; Seufert, Isabelle; John, Lukas; Tirier, Stephan M; Bauer, Katharina; Baumann, Anja; Rohleder, Jennifer; Munawar, Umair; Rasche, Leo; Kortüm, K Martin; Giesen, Nicola; Reichert, Philipp; Huhn, Stefanie; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Stegle, Oliver; Raab, Marc S; Rippe, Karsten; Weinhold, Niels.

Blood ; 142(19): 1633-1646, 2023 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-37390336

4.

Artificial intelligence-based, volumetric assessment of the bone marrow metabolic activity in [¹⁸F]FDG PET/CT predicts survival in multiple myeloma.

Sachpekidis, Christos; Enqvist, Olof; Ulén, Johannes; Kopp-Schneider, Annette; Pan, Leyun; Mai, Elias K; Hajiyianni, Marina; Merz, Maximilian; Raab, Marc S; Jauch, Anna; Goldschmidt, Hartmut; Edenbrandt, Lars; Dimitrakopoulou-Strauss, Antonia.

Eur J Nucl Med Mol Imaging ; 2024 Mar 08.

Artigo em Inglês | MEDLINE | ID: mdl-38456971

5.

Clonal hematopoiesis with DNMT3A and PPM1D mutations impairs regeneration in autologous stem cell transplant recipients.

Stelmach, Patrick; Richter, Sarah; Sauer, Sandra; Fabre, Margarete A; Gu, Muxin; Rohde, Christian; Janssen, Maike; Liebers, Nora; Proynova, Rumyana; Weinhold, Niels; Raab, Marc S; Goldschmidt, Hartmut; Besenbeck, Birgit; Pavel, Petra; Laier, Sascha; Trumpp, Andreas; Dietrich, Sascha; Vassiliou, George S; Müller-Tidow, Carsten.

Haematologica ; 108(12): 3308-3320, 2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-37381752

6.

Stem cell collection after lenalidomide, bortezomib and dexamethasone plus elotuzumab or isatuximab in newly diagnosed multiple myeloma patients: a single centre experience from the GMMG-HD6 and -HD7 trials.

Kauer, Joseph; Freundt, Emma P; Schmitt, Anita; Weinhold, Niels; Mai, Elias K; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Raab, Marc S; Kriegsmann, Katharina; Sauer, Sandra.

BMC Cancer ; 23(1): 1132, 2023 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-37990162

7.

Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma.

Chari, Ajai; Vogl, Dan T; Gavriatopoulou, Maria; Nooka, Ajay K; Yee, Andrew J; Huff, Carol A; Moreau, Philippe; Dingli, David; Cole, Craig; Lonial, Sagar; Dimopoulos, Meletios; Stewart, A Keith; Richter, Joshua; Vij, Ravi; Tuchman, Sascha; Raab, Marc S; Weisel, Katja C; Delforge, Michel; Cornell, Robert F; Kaminetzky, David; Hoffman, James E; Costa, Luciano J; Parker, Terri L; Levy, Moshe; Schreder, Martin; Meuleman, Nathalie; Frenzel, Laurent; Mohty, Mohamad; Choquet, Sylvain; Schiller, Gary; Comenzo, Raymond L; Engelhardt, Monika; Illmer, Thomas; Vlummens, Philip; Doyen, Chantal; Facon, Thierry; Karlin, Lionel; Perrot, Aurore; Podar, Klaus; Kauffman, Michael G; Shacham, Sharon; Li, Lingling; Tang, Shijie; Picklesimer, Carla; Saint-Martin, Jean-Richard; Crochiere, Marsha; Chang, Hua; Parekh, Samir; Landesman, Yosef; Shah, Jatin.

N Engl J Med ; 381(8): 727-738, 2019 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-31433920

8.

Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities.

Giesen, Nicola; Paramasivam, Nagarajan; Toprak, Umut H; Huebschmann, Daniel; Xu, Jing; Uhrig, Sebastian; Samur, Mehmet; Bähr, Stella; Fröhlich, Martina; Mughal, Sadaf S; Mai, Elias K; Jauch, Anna; Müller-Tidow, Carsten; Brors, Benedikt; Munshi, Nikhil; Goldschmidt, Hartmut; Weinhold, Niels; Schlesner, Matthias; Raab, Marc S.

Haematologica ; 107(8): 1891-1901, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35045690

9.

Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma.

Dimopoulos, Meletios A; Dytfeld, Dominik; Grosicki, Sebastian; Moreau, Philippe; Takezako, Naoki; Hori, Mitsuo; Leleu, Xavier; LeBlanc, Richard; Suzuki, Kenshi; Raab, Marc S; Richardson, Paul G; Popa McKiver, Mihaela; Jou, Ying-Ming; Shelat, Suresh G; Robbins, Michael; Rafferty, Brian; San-Miguel, Jesús.

N Engl J Med ; 379(19): 1811-1822, 2018 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-30403938

10.

Venetoclax in myeloma: to B, or not to B.

Raab, Marc S.

Blood ; 143(1): 4-5, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38175678

11.

Novel immunotherapies in multiple myeloma - chances and challenges.

Rasche, Leo; Wäsch, Ralph; Munder, Markus; Goldschmidt, Hartmut; Raab, Marc S.

Haematologica ; 106(10): 2555-2565, 2021 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-34196164

12.

B-cell maturation antigen-specific chimeric antigen receptor T cells for multiple myeloma: Clinical experience and future perspectives.

Sellner, Leopold; Fan, Fuli; Giesen, Nicola; Schubert, Maria-Luisa; Goldschmidt, Hartmut; Müller-Tidow, Carsten; Dreger, Peter; Raab, Marc S; Schmitt, Michael.

Int J Cancer ; 147(8): 2029-2041, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-32270481

13.

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.

Walker, Brian A; Mavrommatis, Konstantinos; Wardell, Christopher P; Ashby, T Cody; Bauer, Michael; Davies, Faith E; Rosenthal, Adam; Wang, Hongwei; Qu, Pingping; Hoering, Antje; Samur, Mehmet; Towfic, Fadi; Ortiz, Maria; Flynt, Erin; Yu, Zhinuan; Yang, Zhihong; Rozelle, Dan; Obenauer, John; Trotter, Matthew; Auclair, Daniel; Keats, Jonathan; Bolli, Niccolo; Fulciniti, Mariateresa; Szalat, Raphael; Moreau, Philippe; Durie, Brian; Stewart, A Keith; Goldschmidt, Hartmut; Raab, Marc S; Einsele, Hermann; Sonneveld, Pieter; San Miguel, Jesus; Lonial, Sagar; Jackson, Graham H; Anderson, Kenneth C; Avet-Loiseau, Herve; Munshi, Nikhil; Thakurta, Anjan; Morgan, Gareth J.

Blood ; 132(6): 587-597, 2018 08 09.

Artigo em Inglês | MEDLINE | ID: mdl-29884741

14.

FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.

Brand, Frank; Förster, Alisa; Christians, Anne; Bucher, Martin; Thomé, Carina M; Raab, Marc S; Westphal, Manfred; Pietsch, Torsten; von Deimling, Andreas; Reifenberger, Guido; Claus, Peter; Hentschel, Bettina; Weller, Michael; Weber, Ruthild G.

Acta Neuropathol ; 139(1): 175-192, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31473790

15.

Development and validation of a novel risk stratification algorithm for relapsed multiple myeloma.

Hájek, Roman; Delforge, Michel; Raab, Marc S; Schoen, Paul; DeCosta, Lucy; Spicka, Ivan; Radocha, Jakub; Pour, Ludek; Gonzalez-McQuire, Sebastian; Bouwmeester, Walter.

Br J Haematol ; 187(4): 447-458, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31388996

16.

Understanding mortality in multiple myeloma: Findings of a European retrospective chart review.

Mohty, Mohamad; Cavo, Michele; Fink, Leah; Gonzalez-McQuire, Sebastian; Leleu, Henri; Mateos, Maria-Victoria; Raab, Marc S; Schoen, Paul; Yong, Kwee.

Eur J Haematol ; 103(2): 107-115, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31112311

17.

The Impact of Tumor Heterogeneity on Diagnostics and Novel Therapeutic Strategies in Multiple Myeloma.

Rasche, Leo; Kortüm, K Martin; Raab, Marc S; Weinhold, Niels.

Int J Mol Sci ; 20(5)2019 Mar 12.

Artigo em Inglês | MEDLINE | ID: mdl-30871078

18.

IL-10 inducible CD8⁺ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells.

Plaumann, Julian; Engelhardt, Melanie; Awwad, Mohamed H S; Echchannaoui, Hakim; Amman, Eva; Raab, Marc S; Hillengass, Jens; Halama, Niels; Neuber, Brigitte; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Hundemer, Michael.

Cancer Immunol Immunother ; 67(11): 1695-1707, 2018 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-30128739

19.

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

Kortüm, K Martin; Mai, Elias K; Hanafiah, Nur H; Shi, Chang-Xi; Zhu, Yuan-Xiao; Bruins, Laura; Barrio, Santiago; Jedlowski, Patrick; Merz, Maximilian; Xu, Jing; Stewart, Robert A; Andrulis, Mindaugas; Jauch, Anna; Hillengass, Jens; Goldschmidt, Hartmut; Bergsagel, P Leif; Braggio, Esteban; Stewart, A Keith; Raab, Marc S.

Blood ; 128(9): 1226-33, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27458004

20.

Therapeutic monoclonal antibodies in combination with pomalidomide can overcome refractoriness to both agents in multiple myeloma: A case-based approach.

Baertsch, Marc-Andrea; Hundemer, Michael; Hillengass, Jens; Goldschmidt, Hartmut; Raab, Marc S.

Hematol Oncol ; 36(1): 258-261, 2018 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-28840598

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