RESUMO
UNLABELLED: Slipped capital femoral epiphysis (SCFE) is the most common orthopedic hip disorder affecting otherwise healthy adolescents. The majority of SCFE cases are classified as idiopathic; rarely, it may be secondary to different endocrinopathies including hyperparathyroidism due to chronic renal failure (CRF). However, over the last decades, the association between SCFE and CRF has almost disappeared, probably due to better management of renal osteodystrophy. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC, OMIM no. 248250) is a rare autosomal recessive tubulopathy characterized by renal wasting of calcium and magnesium leading to hypomagnesemia, hypercalciuria, nephrocalcinosis, and CRF. Patients usually show hyperparathyroidism before the onset of advanced CRF caused by FHHNC-related metabolic disturbances. We report on a 15-year-old patient with FHHNC and CRF who developed extreme hyperparathyroidism and high-grade bilateral SCFE after self-discontinuation of supportive treatment of underlying conditions. CONCLUSION: We believe that SCFE was caused not only by untreated CRF but also by metabolic disturbances related to FHHNC. To prevent this complication, careful management of disturbances of calcium, phosphate, and magnesium homeostasis seems to be crucial.
Assuntos
Hipercalciúria/complicações , Hiperparatireoidismo/complicações , Falência Renal Crônica/complicações , Deficiência de Magnésio/complicações , Nefrocalcinose/complicações , Escorregamento das Epífises Proximais do Fêmur/etiologia , Adolescente , Humanos , Hipercalciúria/diagnóstico , Hiperparatireoidismo/diagnóstico , Falência Renal Crônica/diagnóstico , Deficiência de Magnésio/diagnóstico , Masculino , Nefrocalcinose/diagnóstico , Escorregamento das Epífises Proximais do Fêmur/diagnósticoRESUMO
BACKGROUND: Diastematomyelia is a type of dysraphism with a double or bifid spinal cord divided by an osseous septum. This defect often co-occurs with other developmental disorders of the skull or the atlanto-occipital junction. The course may be benign or aggressive. 2. CASE REPORTS: We describe two female patients treated in the Rehabilitation Clinic and the Orthopaedic Department at the Medical University of Lublin in the years 2004 - 2009. The first patient was diagnosed at the age of 20 years to have diastematomyelia at the L3 level and spina bifida occulta at L1- S5 and at the C1 arch. In the other patient, diastematomyelia at the L3 level and spondylolisthesis at L5-S1 were found at the age of 14 years. Initially both patients were treated for lumbosacral radicular syndromes. Physiotherapy intensified the pain. The patient with diastematomyelia and L5-S1 spondylolisthesis had L5-S1 segment stabilization performed at the age of 16. The pain subsided after the surgery. The other patient was instructed to stop rehabilitation, follow a balanced lifestyle, and refrain from physical work, which eliminated the pain. DISCUSSION: Managing a patient with diastematomyelia demands caution. Diagnosis of this defect requires a thorough cause-and-effect analysis of the presenting signs and symptoms of spinal dysfunction. The treatment should be dependent on local pain intensity (which is often not directly associated with the disorder) and on the degree of neurological dysfunction. 5. CONCLUSIONS: 1. A thorough clinical evaluation with spinal imaging prior to elective surgery for scoliosis and other spine deformities should be a standard procedure undertaken in order to avoid complications. 2. The treatment for diastematomyelia should depend on the intensity of local pain and on the level of neurological dysfunction. 3. Broadly understood rehabilitation is not always effective, often increasing the pain and/or neurological complaints.
Assuntos
Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/cirurgia , Defeitos do Tubo Neural/diagnóstico , Defeitos do Tubo Neural/cirurgia , Adolescente , Descompressão Cirúrgica , Feminino , Humanos , Defeitos do Tubo Neural/complicações , Radiografia , Espinha Bífida Oculta/complicações , Espinha Bífida Oculta/diagnóstico , Espinha Bífida Oculta/cirurgia , Espondilolistese/complicações , Espondilolistese/diagnóstico , Espondilolistese/cirurgia , Resultado do Tratamento , Adulto JovemRESUMO
Background. Metal intraosseous implants cause disturbances in tissue bioelectrity.
Material and methods. Our research involved a group of 28 patients treated by distractive osteogenesis and 12 dogs treated for long bone fractures with external fixation.
Results. During the process of limb lengthening excessive electrical potentials were generated, considerably exceeding the physiological level.
Conclusions. The observed effect may have a negative effect on osteogenesis and remodeling of the regenerating bone. The application of an external fixator did not significantly increase electrical potentials in animals.
RESUMO
Background. The metal element of an external stabilizer cause changes in the electrical potential of tissue. During limb lengthening, large differences in potential are generated between the apparatus and the limb. According to some authorities this phenomenon may have a negative impact on the rebuilding of bone.
Material and methods. In 10 children undergoing limb lengthening by Ilizarov distractor, we applied an original device to eliminate undesirable electrical potentials produced by the introduction of metal distractor implants to tissues.
Results and Conclusions. It was found that the prototype "eliminator" effectively maintains the level of electrical charge within physiological limits.
RESUMO
UNLABELLED: Gradual limb lengthening with external fixators using distraction osteogenesis principles is the gold standard for treatment of limb-length discrepancy. However, long treatment time is a major disadvantage of the current lengthening procedures. Efforts to decrease the treatment include biological and biomechanical factors. Injection of platelet-rich plasma (PRP) is a biological method to enhance bone healing during distraction osteogenesis. We hypothesised that PRP can enhance bone healing during limb lengthening. We report our experience with the use of PRP during distraction osteogenesis. This retrospective study included 19 patients divided into the standard group of 10 patients who did not receive PRP and the PRP group of nine patients who received PRP at the end of the distraction phase. The study variables included external fixator time, external fixation index, and complications during treatment. The PRP group had statistically significantly shorter treatment time (p=0.0412). Injection of PRP into regenerate bone might be an effective method to shorten treatment time during limb lengthening and lead to better functional outcomes and improved patient satisfaction. LEVEL OF EVIDENCE: Level IV, therapeutic study.